This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

Isotopic insights on human diet from the later stone age to Neolithic in Northwest Africa, Morocco

Promotor: J. Schaye

In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.

Heterogeneous catalysis is essential to many industrial applications. These catalysts are often comprised of supported nanoparticles, which contain various different surface sites.

On 22 February, Elody Hutten defended the thesis 'Tax Professionals Under Societal Pressure: A Dutch Case Study on Responses to BEPS'. The doctoral research was supervised by Henk Vording en Jan Vleggeert.

Bob van Grieken and Jaroslaw Kantorowicz published an article in the journal Geopolitics which explores the determinants of China's official financing of Pacific Island states.

This volume, featuring sixteen contributions from leading Roman historians and archaeologists, sheds new light on approaches to the economic history of urban craftsmen and traders in the Roman world, with a particular emphasis on the imperial period.

The dissertation by Max Kusters (PhD at ICLON) examined ‘teacher agency’: the capacity of university lecturers to actively and purposefully influence their teaching practices and work conditions.

On April 26th, Kate Bellamy succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Kate on this great result.

Promotor: Prof.dr. J. Kuiper

The contributions in this volume seek to highlight the atypical features of the Hanse, and place them in a wider context of common roots, influences and parallel developments.

The Iberian Peninsula has been central to the discussion as it was considered to be a 'last refuge' for the species at a time when H. sapiens occupation spread throughout Europe. Much speculation has centred around the idea that extreme climate fluctuations during Marine Isotope Stage (MIS) 3 like Heinrich…

A teacher perspective

Work placement as a professional development programme for vocational teachers has been widely implemented. This dissertation provides insight into vocational teachers’ learning process in this programme within Chinese vocational education.

Intelligence scholars have been struggling to find the conditions under which international intelligence cooperation occurs. Most focus on transactional motives and guaranteed returns, the so called ‘Quid pro Quo’. At the same time, trust is often mentioned as one of the foremost conditions, yet it…

Hermeneutics and the Humanities: Dialogues with Hans-Georg Gadamer / Hermeneutik und die Geisteswissenschaften: Im Dialog mit Hans-Georg Gadamer

On Wednesday 14 February 2024 Yorum Beekman successfully defended a doctoral thesis and graduated.

Large carnivore population is globally declining as a result of the fragmentation of habitat, large prey depletion and retaliatory killing by pastoralists.

Material culture and the role of rural communities in exchange systems of the eighth and ninth centuries

Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink

A thorough description of the relationships among languages and their social environment in a given context, reflecting an ecological perspective, involves attention to the agency of local actors, and the policies, discourse, and ideologies that surround them.

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

Linde Desmaele explores how the United States is recalibrating its stance on European unity amid growing strategic competition with China.

Historicising Art and Literature is one of the six research themes of the LUCAS Modern and Contemporary cluster.

On the 25th of September, Yufang Wang successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Yufang on this achievement!

In summary, the collective results described in this thesis show that nanoparticulate vaccines can be delivered intradermally by coated and hollow microneedles and evoke antigen-specific immune responses.

Membrane fusion is a vital process in living organisms and is mediated by zipper-like proteins.

In this article, Tom Buitelaar proposes a systematic framework for analyzing the impact of individual characteristics of peacekeeping leaders on the behaviour of field-level personnel in UN peacekeeping operations.

On the 28th of September, Jiang Wu successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Jiang on this achievement!

This article by Honorata Mazepus and Florian van Leeuwen in the journal Governance: An International Journal of Policy, Administration and Institutions looks at how evaluations of authorities were influenced by four aspects of a governmental response to a hypothetical disaster.

Julia Prümmer, Tommy van Steen & Bibi van den Berg evaluate the effectiveness of cybersecurity training programs for end-users.

Interaction between Legal Systems acknowledges that law-making and law enforcement are increasingly taking place on various levels: in a global context, in EU context, on a national level and in a private law framework. These levels influence each other, sometimes directly, on the basis of a hierarchical…

Tax scandals, like the Panama Papers, the Paradise Papers, and the Pandora Papers, have made taxation a major topic of public debate. Learn more about this in the new minor Tax and Society: Building a Sustainable and Fair Tax System.

The MSc Dutch Politics at Leiden University offers in-depth insight into contemporary political dynamics in the Netherlands, including parties, public policy, governance, and societal challenges.

The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.

Argumentation and rhetorics is the study of how we convince people verbally. In other words, what do people say and how do they say it?

Doctors are expected to apply recent insights from research to improve patient care. This is one of the reasons for integrating research into medical education.

In this article, Seda Gürkan & Rosa Sanchez Salgado show which emotions the Members of European Parliament (MEP) expressed in the wake of Qatargate.

n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.

To contribute to the body of knowledge aiming at a better coverage of ecosystem service assessment in LCA studies, this thesis dives into the challenges of incorporating existing ecosystem service methods within the impact assessment phase of the conventional LCA framework.

This thesis manuscript explores the use of video games as tools for conceptual exploration and academic research.

This book by Damien van Puyvelde provides the first comprehensive English-language account of France's modern foreign intelligence and explores its evolution, operations, and role in global security.

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

On the 17th of September, Jermy Balukh successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Jermy on this achievement!

The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.

The PML specialisation prepares you with knowledge and understanding of the key concepts and theories of management, leadership, decision-making and policy implementation in national and international government organizations.

Nadine Raaphorst wrote an chapter for The Oxford Handbook of Administrative Justice about how two notions of fairness are studied in street-level bureaucracy literature and about the factors that influence how bureaucrats behave in this regard.

The book explores how ceramic studies illuminate interactions among ancient Mediterranean communities. By integrating post-colonial perspectives and network analysis, the volume transcends traditional

Behavioral and neural mechanisms underlying risky decision-making in adolescents