Promotor: F. Arbab

This research investigates the impact of socioeconomic developments on the physical condition of medieval populations in Holland and Zeeland between AD 1000 and 1600 through the analysis of human skeletal remains from three archaeological sites.

This thesis applies data mining in commercial settings in the telecommunications industry.

This grammar provides a description of Sunwar, a Tibeto-Burman language spoken in eastern Nepal, based on data collected during twelve months of field work.

The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.

Why does one person radicalize to involvement in terrorist violence within a group-based context, while another engages in this form of violence alone?

Both the Dutch government and the European Commission dedicate an increasing share of public funding for research and innovation to mission-oriented programs, aiming to facilitate sustainability transitions. These programs typically involve support fora range of different research activities, from the…

Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

Caribbean archaeological heritage is threatened by natural impacts but also increasingly by economic developments, often resulting from the tourist industry. The continuous construction of specific projects for tourists, accompanied by illegal practices such as looting and sand mining, have major impacts…

The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.

“Temminck’s Order” is the scientific biography of Coenraad Jacob Temminck (1778–1850), a Dutch naturalist and the first director of ’s Rijks Museum van Natuurlijke Historie in Leiden.

Promotores: G. Persoon, R. Schefold

HomininSpace is an agent based modelling and simulation system in which fluctuating carrying capacity is the key attractor for hominin dispersal. A parameterized and spatially explicit reconstructed palaeo-environment models available energy in the form of secondary biomass using reconstructed climate…

Legibility in the Age of Signs and Machines offers a compelling reflection on what the notion of legibility entails in a machinic world in which any form of cultural expression – from literary texts, films, artworks and museum exhibits to archives, laws, computer programs and algorithms – necessarily…

There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.

One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.

Promotor: Prof.dr. M. Danhof, Co-promotor: O.E. Della Pasqua

Promotor: Prof.dr. H.J.A. Rottgering, Co-promotor: David Sobral

This book explores the relationship between tragedy and the justice that is sought in moral philosophy and the law. It shows how our moral and legal judgments can be seen as aesthetic or tragic judgments, and it considers what kind of passion or vocation moves the science and scholarship of law.

Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez

This dissertation shows that dialogical logic constitutes a powerful and flexible general framework for the development and study of various logical formalisms and combinations thereof.

The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.

Early time-resolved experiments by Frauenfelder on the ensemble of the kinetic rebinding of CO to myoglobin molecules resulted in a stretched exponential relaxa-tion due to a very large spread of the reaction rates of individual molecules.

Biopolymer sequencing with graphene edge-based tunnel junctions has the potential to overcome current limitations with the third generation of sequencing based on biological nanopores.

Multi-Angle Dynamic Light Scattering (MADLS) is a technique that is used to determine properties of particles in suspension. The measurements give the hydrodynamic size distribution of individual particles as well as particle clusters, and assists in the interpretation of the stability of the particles…

What was the nature of the urban network in the Roman provinces of Germania Superior, Raetia and Noricum and how stood this in relation with economic and social developments?

On 12 mei 2020, Darryl Robinson defended 'Exploring Justice in Extreme Cases: Criminal Law Theory and International Criminal Law'. The doctoral research was supervised by Prof. C. Stahn.

MICRO-biome climate smart applications: Can we use indigenous microbial rice communities to reduce methane production in agricultural settings?

In the Brill series Intersections a new volume has been published, entitled Ronsard and Du Bartas in Early Modern Europe.

Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.

Quantifying physical activity (using accelerometers) and combining the frequency and intensity of activities with health data (brain MRI, traditional clinical parameters and metabolomics) is of utmost importance to monitor mobility and health among older individuals and study health promotion during…

The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.

This study documents and translates the Saa (Zapotec) cultural heritage of the Bene’ Ya’a/En’ne I’ya peoples, the Zapotec inhabitants of the Sierra Norte of Oaxaca.

This book collates thematic reflections on Cameroon music exalting Manu Dibango, one of the first-generation Cameroonian musicians, who bowed to Covid-19 on 24 March 2020.

A vibrant chronology of ceramic manufacturing practices in the valley of Juigalpa, Chontales, Nicaragua (cal 300 CE - present)

This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.

Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe

This study tests whether behavioural problems at a young age are related to early reading and mathematics development.

Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.

Andrea Bartolucci is Assistant Professor at Institute of Security and Global Affairs. In this study, the scholars adopted a multidisciplinary approach to investigate wildfire risk in Van Chan district in northern Vietnam, a region where official data are sometimes difficult to collect or inconsisten…

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

This thesis discusses several questions regarding the double ramification cycle as a Chow class on the moduli space of stable n-pointed genus g curves using tools from so-called logarithmic geometry.

Carbohydrates, or sugars, are the most diverse and most abundant biomolecules known. However, the isolation of carbohydrate samples in sufficient amounts and purity is often impractical or even impossible, so the chemical synthesis of glycosides becomes relevant. The glycosylation reaction, in which…

Anthropogenic noise has been shown to affect marine animals in various ways, this may have fitness consequences at individual and population level. This thesis aims to increase insight into the quantification of sound-induced behavioural responses that are relevant to fitness, and into factors that…

Promotor: F.P. Israel, Co-Promoter: R. Meijerink

On the 12th of September, Lorenzo Nespoli successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Lorenzo on this achievement!

From deepfakes and disinformation to killer robots, surgical robots and AI lawmaking: AI (Artificial Intelligence) is changing our world. That raises the question whether this requires some form of regulation. At eLaw, the Center for Law and Digital Technologies at Leiden University, prof. Bart Custers…

Over the last decades, income inequality has increased globally. How do social policies affect this increasing trend? How do international trade and technological progress affect inequality? What is the profile of income inequality in China?

‘The storm of the passions rages’: The works of Johannes Jelgerhuis as a source of stagecraft for the historically informed performer.