Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

As of 1 July, Professor of Mathematical Biology Roeland Merks has got a full appointment at Leiden University. Before this expansion, he worked one day a week at the Mathematical Institute (MI). Merks will work half of his full appointment at the MI and the other half at the Institute of Biology Leiden…

If you are interested in Life Science and you are looking for a programme with ample opportunities to put together your own study path, our Life Science and Technology programme is the right choice. The programme focuses on societal problems at the molecular and cellular level.

Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.

Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.

This thesis is about the study of hydrocarbons via infrared spectroscopy.

This project aims at describing the Khoisan languages !Ora (Korana/Griqua) and !Ui of South Africa.

150 new Biology students have arrived in Leiden. This is more than ever and we seem to settle among the big three Universities for Biology in the Netherlands.

On February 24, 2017, the Institute of Biology Leiden organised the first edition of the Biology Career Event. The career event for third year bachelor and master students was well received by the attendants. ‘I felt that the presenters and people doing the workshops were really trying to help us get…

The INTERACT project strive to unlock the enormous biotechnological potential of microbes, leading to sustainable crop productions systems.

Biology student Britt van Kasterop has received a Holland Society Young Talent Award for her excellent results in the first year of study. The online awards ceremony took place on 30 November.

1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…

The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…

The adsorption of D2 and CO2 on catalyst surfaces is studied using a molecular beam in ultra-high vacuum.

There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…

Bacteria are everywhere. They are the most abundant organisms on earth and impact all aspects of our lives. They determine our health and shape our environment. Ariane Briegel, professor of Ultrastructural Biology, freezes bacteria super fast to gain a true-to-nature image of the internal and external…

Promotor: F.P. Israel, Co-Promoter: R. Meijerink

The research provides insight into disease behavior in both rural and semi-urban areas in Serengeti in Tanzania.

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Promotores: A.H. Meijer, H.P. Spaink

Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar-Jagalska

This thesis has described novel synthetic methods to produce a variety of (glyco)peptides and their application in the study of various immunological processes.

The subject areas covered encompass functional genomics, signal transduction, cellular differentiation, development, host-microbe interactions and animal behaviour.

A structural investigation of coiled coil peptides used as membrane fusogens, mimicing naturally occuring coiled-coil fusion proteins. Synthetic modifications have been made to alter lipid attachment, secondary structure and to insert photoactive azobenzene moieties for active control over coiled coil…

Can Cyanobacteria be engineered to convert the greenhouse gas carbon dioxide into the valuable chemical isoprene?

Evolution is all around you every day. This is the message of a Massive Open Online Course (MOOC) of Leiden University and Naturalis that is offered free of charge to anyone interested.

Since May, Assistant professor BioTherapeutics Lu Su works in our faculty. Although she is still young, she already worked in many different fields and co-operated on two publications in big scientific journals. How did she become so successful and what motivates her to keep researching the possibilities…

During the spring of 2021, a group of eight biology students from Leiden set out into the dunes in search of amphibians. Using DNA, they determined the geographic origin of the animals. And guess what? In many cases they discovered exotic populations of animals that do not naturally belong in The Netherlands.…

The students of iGEM Leiden 2021 have scored well in the eponymous biology competition: they won a Gold Medal and the Best Safety & Security Award. The student team received the awards for their project DOPL LOCK, in which the team tries to make genetic modification safer.

The Quantitative Pharmacology group headed by Coen van Hasselt focusses on the application of state-of-the-art quantitative pharmacometrics and systems pharmacology modeling combined with translational experimental models to develop personalized treatment strategies for antibiotics and to combat antimicrobial…

It is the dream of Professor Susana Chuva de Sousa Lopes to grow fertile egg cells in the lab. But she says there is a long way to go in her discipline until that is possible. This is the message of her inaugural lecture on 29 June 2020, the first digital inaugural lecture at Leiden University.

Martijn Verkuilen is the winner of the Unilever Research Prize 2022. By transferring DNA from a plant into yeast, he made the first move to produce a new drug for type 2 diabetes. He collected his prize in Wageningen on 24 November.