Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.

EUMOTIONS explores the role of emotions expressed by political elites (at EU- and member state-level) in framing the EU’s policy options during international crises.

This article argues that opposition to government green investments is conditional on the method of financing.

The thesis is about how auxin and AGC kinases regulate male fertility. The main AGC kinases studied in this thesis is PDK1, PDK2 and AGC1.5, AGC1.7.

Source: ChemMedChem (2015)

OSCL members, amongst which our representative in the Archaeology faculty, were part of Data Carpentry for Social Sciences. Here's what happened.

Somatic symptoms, such as pain, itch, and fatigue have been shown to have a bidirectional relationship with mental symptoms. Although acute somatic symptoms serve some adaptive properties, chronic symptoms can instead lead to interference in daily activities and lower quality of life.

In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.

It is the end of your archaeological research project, and you may be wondering where to deposit your data. After the excavation, all of the finds are drawn, scanned, digitised, and the database is completed. Perhaps you have also accumulated a lot of data through further scientific analysis of the…

This project combines an extensive new open database on linguistic distributions, spatial modelling and areal linguistics in order to disentangle the roles of social and environmental factors on the emergence of linguistic diversity patterns of South America.

On January 31, 2018 the Data Economy Conference will take place in Budapest. The conference is organized by IVSZ within the EuDEco project. It’s going to be an interesting event with many knowledgeable speakers.

In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.

Biologists today have to be able to work with big data. Data analysis skills should be taught from the start of the degree programme, or - even better - in secondary school. This is the message of Vera van Noort, new Professor of Computational Biology. Inaugural lecture 22 January.

Whilst the world is opening up, the teaching will continue in a hybrid form next academic year. During the past year, when all of us were bound to our home offices and computer screens, new forms of education had to be developed – some of which proved to be efficient in preparing the students for their…

In this PhD study, I aim to deepen our understanding of the influence of major mycorrhizal types, namely arbuscular mycorrhizae (AM) and ectomycorrhizae (EM), on the global soil carbon cycle and their potential distribution changes under future environmental shifts.

In this project, the hypothesis that language contact crucially impacts the development of spatial grammar and phonology is investigated.

Chemical tools to monitor drug-target engagement of endogenously expressed protein kinases are highly desirable for preclinical target validation in drug discovery. Here, we describe a chemical genetics strategy to selectively study target engagement of endogenous kinases.

It is becoming increasingly common to collect data from children and young people through digital means. The impact of this so-called ‘dataveillance’ on children, who are monitored from birth via smartphones and Fitbits, is great.

The research programme Statistical Science is concerned with the analysis and interpretation of masses of data, the quantification of uncertainty using probability models, and the development and benchmarking of algorithms and methods with these aims.

Speed skating coach and human movement scientist Jac Orie has been capturing all details about the performance of 'his' skaters for fifteen years. Thanks to data scientist Arno Knobbe, who calculates the collected data in new ways, Orie can train his team even smarter in the run-up to the Olympic Winter…

On 29 November 2022, Jan Aart Scholte and colleagues presented the project 'Digital Data: Polycentric Governance Perspectives' at the United Nations Internet Governance Forum in Addis Ababa. Click here to find out more about the event.

In this thesis, deep learning is studied from a statistical perspective. Convergence rates for the worst case risk bounds of neural network estimators are obtained in the classification, density estimation and linear regression model.

To what extent are there differences between countries in and outside the European Union and the Schengen area in the level of crimmigration, the merger between migration control and crime control, and to what extent can these differences be explained by the way in which state and non-state actors in…

Prof.dr.ir. Hai-Xiang Lin is appointed on 1 March 2015 as part-time professor on Data Analytics for Environmental Modelling at CML on behalf of the R. Timman foundation. He will join the CML-department of Industrial Ecology. He has a position at the Department of Applied Mathematics at the Faculty…

This paper written by Vydra and Kantorowicz answers the research question ‘What policy-relevant information does Twitter contain?’ as well as the research question ‘How does this information change between a period of normalcy and a period of crisis?’

Computer scientist Matthijs van Leeuwen is one of four science faculty members who obtained the Senior Qualification in Education in 2021. What was that like and what drives him? ‘In my own education I would have liked to see more attention paid to the responsibility that machine learning and data mining…

On 16 May 2022, Professor Michel Wouters from the Department of Biomedical Data Sciences at the Leiden University Medical Centre (LUMC), will deliver his inaugural lecture titled ‘Quality of Cancer Care: why the real world matters’. Wouters will use the opportunity to describe how quality registries…

From toy cats that purr to robot dogs that bark: what do such technologies mean for older people, healthcare providers and family members? A Dutch Research Council (NWO) Veni grant is enabling anthropologist Tanja Ahlin to investigate how animal-shaped robots can contribute to care for older people…

How do governments distribute resources across economic sectors during a crisis? And why do some sectors receive more than others? The recent COVID-19 pandemic has highlighted the urgency of these questions. In this paper, we explore the extent to which a political economy…

How and when do interest groups organise themselves as transmission belts and what are the implications for their political relevance among public officials involved decision-making processes?

This study explores public leaders’ organizational learning orientation in the wake of a crisis. More precisely, we study the association between public leaders’ public service motivation and their learning orientation (instrumental versus political).

L1-oral language education is widely regarded as essential for developing communicative competence and critical thinking. However, as a research domain it remains relatively underexplored. The aim of this study was to identify effective elements and challenges within oral language education and to contribute…

The world is becoming increasingly digitised, and the information one has easy access to is often rather overwhelming. In particular, the accumulative nature of the archaeological practice has resulted in huge quantities of data being produced. But how to prevent these from becoming dust-collectors…

Seminar 12th of April

On 15 February 2018, Simone van der Hof gave a keynote lecture entitled 'Data Protection and Children's Rights - the reasoning behind the protective provisions for children in the GDPR' at the International School of Amsterdam conference on Strategic marketing & communications for international scho…

Quantum computers are a proposed fundamentally new type of computer. They aim to perform some computations much faster than previously possible by exploiting phenomena at the quantum scale, called superposition and entanglement.

The coronacrisis is emerging as the ultimate test for political leaders. How do national political leaders get ahead or behind ‘the curve’ of fast-changing dynamics. Martin Lodge (London School of Economics and Political Science) and Arjen Boin (Leiden University Institute of Political Science) look…

A technique originally developed for satellite imaging can now be used to recover pictographic texts from underneath the surface of a five hundred year old Mexican manuscript.

The growing popularity of corporate self-regulation to address supply-chain issues puts Corporate Social Responsibility and specifically codes of conduct, at the centre of attention. In this article, Jaroslaw Kantorowicz, Sarah Vandenbroucke and Yvonne Erkens analyse supplier codes of conduct of multinational…

PhD defence