4,709 search results for “active studies” in the Public website
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A brain-wide map of neural activity during complex behaviour
A key challenge in neuroscience is understanding how neurons in hundreds of interconnected brain regions integrate sensory inputs with previous expectations to initiate movements and make decisions.
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inhibitors selective for human constitutive proteasome and immunoproteasome active sites
This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.
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Transnational Anti-Communism and the Cold War: Agents, Activities, and Networks
How was anti-communism organized in the West? New volume edited by Giles Scott-Smith, Luc van Dongen and Stephanie Roulin on the aims, arguments and associations of a range of transnational anti-communist activists during the Cold War.
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Upconverting nanovesicles for the activation of ruthenium anti-cancer prodrugs with red light
Promotor: E. Bouwman, Co-promotor: S. Bonnet
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Increased striatal activity in adolescence benefits learning
Heightened activation of the striatum that adolescents show in response to reward is often associated with risk-taking and negative health consequences. This article in Nature Communications investigates a potential positive side of this heightened activation. It shows that the activity peak in late…
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Information activities
Do you want to know more about Cultural Anthropology and Development Sociology and what it is like to study in Leiden? Come to our online or on campus information events.
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Channa LiFaculty of Humanities
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UN celebrity diplomacy in China: activism, symbolism and national ambition online
In this article in International Affairs, Saskia Postema and Jan Melissen examine Chinese celebrities' UN-affiliated Weibo activism in the context of China's increasing engagement in the United Nations, which coincides with a shrinking domestic public sphere under Xi Jinping's leadership.
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Chemical biology studies on retaining exo-β-glucosidases
The research described in this thesis centered on retaining exo-β-glucosidases implicated in health and disease, in particular the human inherited lysosomal storage disorder, Gaucher disease (GD).
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receptor ligand profiling reveals biased signalling and off-target activity, Nat. Commun., 2017
The cannabinoid CB2 receptor (CB2R) represents a promising therapeutic target for various forms of tissue injury and inflammatory diseases. Although numerous compounds have been developed and widely used to target CB2R, their selectivity, molecular mode of action and pharmacokinetic properties have…
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The Future of the Dutch Colonial Past: Curating Heritage, Art and Activism
This book provides an overview of critical scholarly reflections on the history of Dutch slavery and colonization, as well as how this translates into critical cultural practices.
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Nico KapteinFaculty of Humanities
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Dennis HetterscheidFaculty of Science
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Peter VerhagenFaculty of Humanities
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Ab de JongFaculty of Humanities
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Activating education for first year law students: Evaluating the new Ateliers
In what ways does Atelier education contribute to skills development, active learning, interactions between students and staff, and connections between disciplines of law?
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Joel RüeggerFaculty of Science
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Daan van der VlietFaculty of Science
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Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and
Source: Mol Psychiatry (2015)
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Xiao LuoFaculty of Humanities
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Boudewijn WalravenFaculty of Humanities
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Haneen OmariFaculty of Humanities
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Maghiel van CrevelFaculty of Humanities
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On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases
Active-site directed probes are powerful in studies of enzymatic function. We report an active-site directed probe based on a warhead so far considered unreactive.
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Hermen OverkleeftFaculty of Science
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A community computational challenge to predict the activity of pairs of compounds
Source: Nat Biotechnol, Volume 32, Issue 12, pp. 1213-22 (2014)
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Inhibitors and activity-based probes for β-D-glucuronidases, heparanases and β-L-arabinofuranosidases
Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.
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Henk Schulte NordholtKoninklijk Instituut Taal, Land- en Volkenkunde
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William Michael SchmidliFaculty of Humanities
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Francesca RosatiFaculty of Humanities
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Steven HagersFaculty of Humanities
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Geoffrey CainFaculty of Humanities
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Yusra AbdullahiFaculty of Humanities
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Far-Right Activism: A Comparative Analysis of the Motivating Factors Driving Men and Women to Engage in Far-Right Social Movement Activism in the
In the present-day United States, to what degree(s) are far-right men and women similar and/or dissimilar in their motivating factors for engaging in far-right social movement activism?
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Intersectional activism: Dutch-Turkish Muslim women 'talking back' to securitization and Islamophobia
This article investigates the efforts of influential Turkish Muslim civil society actors to amplify the voices of Muslim women in the Netherlands.
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education: design, implementation and evaluation of group learning activities
The aim of this study was to provide insight into how teachers in higher education can be supported in the design, implementation and evaluation of group assignments by developing a theoretical and evidence-based framework for the design of group assignments.
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Turkish Studies
Welcome to the website of Turkish Studies at Leiden University. On this website you will find information on the work and the activities of the people studying the Ottoman Empire and Turkey at Leiden University.
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Edegar Da Conceição SavioFaculty of Humanities
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Arfi ArfiansyahFaculty of Law
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Crewe WilliamsFaculty of Humanities
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Amirardalan EmamiFaculty of Humanities
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Xiong XiongFaculty of Humanities
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Unraveling modular architecture and domain engineering of carbohydrate-active enzymes: key insights for sustainable bio-based processes
This thesis examines enzyme domain architecture and engineering to improve the breakdown of lignocellulose and starch, abundant biopolymers crucial for sustainable biofuel and biochemical production. Carbohydrate-active enzymes (CAZymes) facilitate this degradation, but the structural complexity of…
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Active Acquaintance for 130 new BA Archaeology students: ‘Wellbeing, study succes, and having fun is all connected’
Every year the newly arriving Archaeology students are invited to join an active introduction day during which they get to know the Faculty and each other in a playful and fun way. The activities are organised by Study Adviser Cleody van der Eijk. ‘It helps people to loosen up and get to know each o…
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Caroline Fernandes CaromanoFaculty of Humanities
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Macrophage activation and cholesterol accumulation in atherosclerosis development
Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck
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Towards near-infrared light-activated combination chemotherapy
The goal of the research presented in this thesis was to explore the chemical space of ruthenium(II) photocages, investigate their ability to host potent chemotherapy drugs, and to red shift the activation wavelength of the most promising PACT candidates to conduct biological studies.
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HAS information activities| Master’s in Health, Ageing and Society
Discover the HAS master at Leiden University – LUMC. Join the Experience Day and student for a day with a mini lecture, case study, and meet students and alumni.
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Pair configurations to molecular activity coefficients: PAC-MAC
This thesis provides an overview of the development of the Pair Configuration to Molecular Activity Coefficient (PAC-MAC) model.
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biosynthesis in Streptomyces: engineering, resistance and antimicrobial activity
Actinobacteria are well known for the production of bioactive natural products, many of which have applications in the fields of human, animal and plant health. Subject of this thesis are the anthracyclines, glycosylated aromatic polyketides with potent anticancer activity.
