The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

This dissertation provides an overview of the phonological developments of the Qinghai-Gansu languages, comparing them to the reconstructed ancestral language.

Innovation plays an essential role in firms' competitiveness and long-term success. It varies from different types, ranging from run-of-the-mill innovation that brings incremental changes to existing technologies to radical innovation that breaks from existing trajectories.

Promotor: Prof.dr. T. Hankemeier, Prof.dr. J.C.T. Eijkel (Twente University)

This dissertation is about Bayesian learning from data. How can humans and computers learn from data?

Following the Big Bang, structure in the Universe started collapsing under the force of gravity. This resulted in the formation of the first stars, galaxies and clusters of galaxies.

The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.

Tuna Kalaycı, ed. Archaeologies of Roads. 2023.

Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.

Observational, cognitive and physiological measurements in social contexts.

Promotor: Prof.dr. R.M.H. Merks

At Leiden University we like to stay in touch with our alumni. We therefore invite you by post, email or phone to lectures, workshops and masterclasses for alumni and inform you about developments in your field and at the University. With your knowledge and experience, you also make a valuable contribution…

From William Shakespeare to Marilynne Robinson, A Literary History of Reconciliation is the first study to examine representations of interpersonal reconciliation in work of literature across a long-term period, from the early seventeenth century to the present day, focusing on how these representations…

This project proceeds from the observation that since the second half of the twentieth century, forgiveness and reconciliation have become pervasive themes in western culture, both on a political level and in personal relations.

The Institute of Security and Global Affairs (ISGA) is a scientific institute that specialises in security issues.

Early Childhood Community Practitioners’ analyses of new mother’s challenges in Alexandra Township South Africa: a collaboration between academics and practitioners

Visit an exhibition, a concert or learn to paint.

GLOBALINT is a pioneering study of intelligence in the Global South. It asks ‘how do (un)democratic shifts in political governance impact intelligence services in contexts of violent conflict?

Water Management, Agricultural Practices, and Social Complexity in Southern Turkmenistan during the Bronze Age

The studies reported in this thesis were situated in the context of an innovation of Dutch secondary school biology curricula. As in any innovation, the practical knowledge of teachers determine the outcomes through the decisions they make while planning and teaching their lessons. The aim of the studies…

Some species of proteins which can form liquid-like condensates, also exhibit growth into fibers (or fibrils). One particularly interesting set of such proteins are those that are associated with neurodegeneration in which the fiber growth may be related to the pathological fibrils observed in disea…

This volume investigates how urban growth and prosperity transformed the cities of the Roman Mediterranean in the last centuries BCE and the first centuries CE, integrating debates about Roman urban space with discourse on Roman urban history.

On the 4th of June, Saskia Lensink successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Saskia Lensink on this achievement!

Our everyday life consists of all sorts of spatial processes: we find our way to work, remember where we left our keys, and are able to pick up our cup of coffee. We study how the human brain processes such spatial processes. From a clinical perspective, we are interested in how acquired brain damage…

On 26 November 1940 Rudolph Pabus Cleveringa (1894-1980) gave his now famous protest speech.

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

On 30 June 2016, Eesa Fredericks is expected to defend his Ph.D.-thesis ‘Contractual Capacity in Private International Law’ in Leiden. Supervisors are prof. Sierd J. Schaafsma (Leiden) and prof. Jan Neels (Johannesburg).

Mechanobiology is a major area in biology, however, mechanics is currently a missing element in drug development pipelines. This has led to a high cost for the society. Mechanotoxicity of drugs often appears as a long-term side effect of drugs, and has led to removal of drugs from the market. Furthermore,…

Molecular materials have been a subject of interest in fundamental research and applications for decades, and have been studied as bulk crystals, (thin) films and as individual molecules, due to the large variety in their properties. This dissertation explores pentacene crystals near the two-dimensional…

The Indonesian Experience after the Fall of Suharto

Implementation of the new sound synthesis and analysis method in music composition.

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Do you have broad interests and enjoy doing more besides your regular schoolwork? Then you probably always want to know the ins and outs! That is exactly what the Pre-University College is: an extra programme for students who want and are able to do more.

Islam is often studied as a distinct and uniform phenomenon that is or should be kept private, and stands apart from any other human activity, be it in the field of economics, law or politics.

A publication on the location of financial losses and the validity of jurisdiction clauses after the CJEU’s Kolassa v Barclays Bank and Profit Investment v Ossi judgments.

On 18 september 2018, Jonathan Price defended his doctoral thesis 'The Egalitarian Constitution'. The doctoral research was supervised by Prof. dr. A.A.M. Kinneging.

The prohibition of anti-competitive unilateral conduct by firms with market power is not absolute, but allows for derogation.

Our courses embrace developments in technology. Our teachers adapt technological innovations to their discipline, and we keep our teaching up to date on rapid developments in the digital world.

Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.

In this article, Ben de Jong, research fellow at the Institute of Security and Global Affairs, examines the relationship between double agents and their handlers.

The Leiden Leadership Programme (LLP) is an interdisciplinary honours programme for master’s students. It is organised by Leiden University's Honours Academy and Leiden Leadership Centre.

In this thesis, we present new laboratory data of interstellar dust analogues.

Promotor: C. W. J. Beenakker, Yu. V. Nazarov, Co-promotor: J. Tworzydlo

This thesis involves three topics: benchmarking discrete optimization algorithms, empirical analyses of evolutionary computation, and automatic algorithm configuration.

An assessment approach that tailors to children’s instructional needs

This study attempts to understand how indigenous community institutions pose an important role in sustainable community-based development, including the integration between local culture and development.

The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.

Arco Timmermans, professor by special appointment in Public Affairs at the Institute of Public Administration, is co-editor of this book focused on comparing engagements in policy advisory systems.

Our previous meta-analysis (Swart et al., 2019) had shown that feedback targeting text comprehension given when students perform a reading task positively influences learning from text. So far, differences in the effects of feedback were explained by design features, such as the timing and richness…

Une étude archéo-anthropologique de la céramique des sociétés caribéennes multiculturelles de la période précoloniale à nos jours