This thesis investigated miniaturized mass spectrometry (MS)-based analytical methods to address challenges in analyzing biomass-restricted biological samples.

Promotor: G.P. van Wezel

On Thursday 27 June 2024 Sigrid van Roode successfully defended a doctoral thesis and graduated.

On the 28th of September, Jiang Wu successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Jiang on this achievement!

In Humanity’s End As A New Beginning, Emeritus Professor Mineke Schipper reflects on myths about ‘the end’.

What physics controls the properties of quantum matter, such as how electrons flow inside high-temperature superconductors? This question has captivated the physics community and industry for decades, in part due to the great technological potential such materials have, but also because they have resisted…

The World of the Fullo takes a detailed look at the fullers, craftsmen who dealt with high-quality garments, of Roman Italy. Analyzing the social and economic worlds in which the fullers lived and worked, it tells the story of their economic circumstances, the way they organized their workshops, the…

This article by Honorata Mazepus and Florian van Leeuwen in the journal Governance: An International Journal of Policy, Administration and Institutions looks at how evaluations of authorities were influenced by four aspects of a governmental response to a hypothetical disaster.

In the early universe, the dynamics of the Higgs field can give rise to many interesting phenomena.

This thesis aims to investigate the effect of tripartite interaction between microbial inoculants, the plant, and herbivore insects on the rhizosphere microbiome and volatilome. We investigated the rhizosphere microbiome and volatilome of tomato plants exposed to insect herbivory and/or inoculated with…

This paper contributes on an increasing body of work on radicalisation. It specifically focuses on what distinguishes individuals whose behavioural radicalisation includes involvement in terrorist violence from those whose behavioural radicalisation does not.

De lichtheid van literatuur: Engagement in de multiculturele samenleving (The Lightness of Literature: Engagement in the Multicultural Society) is a plea for the social relevance of literature. The book delves into an age-old debate about literature and social engagement, which has recently been reinvigorated…

After 20 years of police reform, Jasper De Paepe and Marleen Easton look back and discover what we can learn about partnerships between police and science in Belgium.

Prince, Pen, and Sword offers a synoptic interpretation of rulers and elites in Eurasia from the fourteenth to the eighteenth century. Four core chapters zoom in on the tensions and connections at court, on the nexus between rulers and religious authority, on the status, function, and self-perceptions…

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An important feature of atopic eczema (AE) is a decreased skin barrier function. The stratum corneum (SC) lipids - comprised of ceramides (CERs), free fatty acids (FFAs) and cholesterol - fulfill a predominant role in the skin barrier function.

Julia Prümmer, Tommy van Steen & Bibi van den Berg evaluate the effectiveness of cybersecurity training programs for end-users.

For optimization problems, it is often unclear how to choose the most appropriate optimization algorithm. As such, rigorous benchmarking practices are critical to ensure we can gain as much insight into the strengths and weaknesses of these types of algorithms.

The potential of liposomal cancer vaccines

This study interrogates contemporary and historical uses of barbarism, arguing that barbarism also has a disruptive, insurgent potential.

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

Promotor: Prof.dr. E.F. Smets, Co-promotores: Dr. B. Gravendeel, F. Pupulin

In this article, Gerrit Dijkstra and Jos Raadschelders from the Institute of Public Administration, argue that Bosnia-Herzegovina survives so far on the basis of negative legitimacy.

This book is the first grammar on Ternate Malay, a local variety of Malay spoken on the island of Ternate, North-Moluccas, Indonesia.

This is the first full-scale reference grammar of Classical Greek in English in a century.

The land question had a crucial formative influence on Mayo politics in the decades before the First World War and this book shows the part played by many prominent nationalist figures such as Davitt, O’Brien, Dillon and MacBride in shaping the political landscape in Mayo.

Promotor: K. Kuijken, Co-Promotor: H. Hoekstra

This thesis investigates how cell shape and collective behavior influence the dynamics and structure of biological tissues, which are crucial for understanding processes like embryonic development, tissue regeneration, and metastasis.

Asim Zubcevic defended his thesis on 11 November 2015

The indane (2,3-dihydro-1H-indene) ring system is an attractive scaffold for biologically active compounds due to the combination of aromatic and aliphatic properties fused together in one rigid system.

This dissertation provides a novel perspective on the interaction between quantifier scope and ellipsis. It presents a detailed investigation of the scopal interaction between English negative indefinites, modals, and quantified phrases in ellipsis. One of the crucial observations is that a negative…

The Animated Image addresses the entire range of contexts in which images were described by Roman authors as being animated, as well as the accounts that Roman writers produced to explain the animation of inanimate matter.

Promotor: E.F. Smets Co-promotor: J. Geml

Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.

For several years, contemporary composed music has been critiqued among others by funds, sponsors, and festival organizers for having lost contact with their audiences. This music has increasingly become a pursuit of a privileged, well-situated, and higher educated public, and is most often confined…

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

CML report 192

Promotores: J.A.van Veen, P.L.G.Klinkhamer. Co-promotor: E.E.Kuramae

This dissertation is concerned with the study of the less than twenty remaining precolonial Mesoamerican codices. By considering these rare and fragile pictographic and hieroglyphic books from the cultural biography perspective, many different aspects of these books can be studied.

This thesis describes the use of bioorthogonal proteins in immunological settings. It provides an introduction towards the field of protein modification, which was used throughout the thesis for the expression of proteins containing unnatural amino acids.

Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.

The Cide Archaeological Project: Surveying the Turkish Western Black Sea Region

This thesis is a (biased) journey through very different topics in astrophysics: quasars and new populations of active galactic nuclei, gravitational waves from merging black holes, and protoplanetary discs around young stars.

This dissertation is concerned with the development of grammar. Starting from a usage-based perspective, which holds that children use domain-general learning mechanisms to acquire the grammatical patterns of their mother tongue, Beekhuizen shows how to operationalize various concepts from this tradition…

The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.

Alzheimer's disease (AD) is the most frequent neurodegenerative disorder and the primary cause of dementia. The neuropathological features of AD include the occurrence of senile plaques, neurofibrillary tangles, decreased synaptic density, and loss of neurons. An obstacle in the study and treatment…

Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.

The transition to electric vehicles (EVs) reduces vehicle emissions to combat climate change. EVs raise concerns regarding the production of lithium-ion batteries and related emissions; while batteries can also provide energy storage services for the electricity system.

This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…