Our research is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.

We aim to engineer streptomycetes to fully exploit their potential for natural product productions, by a rational design and evolution approach.

Overview of the CML reports

1. What is the exact role of PIN proteins in PAT? 2. How is PIN polarity established, and how is it modulated by AGC kinase-mediated phosphorylation? 3. What is the role of the AGC kinase, as modulators of PAT, in translating environmental signals, such as gravity, light or mechanical stress, to plant…

Promotor: S.J. Edixhoven Co-promotor: L. van Geemen, P. Parent

Dr Kim Duistermaat (NVIC) en Niels Groot (TU Delft)

What is the provenance of introduced populations?

Analecta Praehistorica Leidensia is the annual journal of the Faculty of Archaeology (formerly the Institute of Prehistory), Leiden University.

Lecture

One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…

Blood, Sweat and Tears: The Changing Concepts of Physiology from Antiquity into Early Modern Europe

This dissertation presents the first full grammatical description of bago ts'amakkilo ('mouth of the Ts'amakko'), or simply Ts'amakko. It is a Cushitic language, spoken in Southwest Ethiopia and belongs to the Dullay cluster of Lowland East Cushitic. The number of speakers is about 10,000. The data…

An overview of awards and prizes granted to our staff and students in 2022, as well as special appointments at Leiden University and other institutions.

Key publications of the Barz Lab

Lecture, Studium Generale

The aim is to develop methods to assess environmental and occupational exposure to (individual) pesticides, to be applied in epidemiological studies investigating pesticide exposure and human health. Furthermore, we aim to investigate the potential association between exposure to pesticides and Parkinson’s…

Research question

Light reflects from a mirror, but where exactly does this reflection happen? Well, it depends, Martin van Exter and Corné Koks discovered. Their precise calculations, published in Optics Express, are important for designing optical cavities for quantum communication.

Leiden physicists use a new method to measure so-called surface plasmons. Researching these particles could lead to new light-based technology, including faster internet.

The starting point for this research project is the notion that the human brain is susceptible to all kinds of fallacies and biases that affect our perceptions and influence our reasoning outside of our conscious awareness. Indeed, most people think they are merely observing facts and that they process…

The aim of the Standard Operating Procedures for Research Integrity (SOPs4RI) project was to promote excellent research and a strong research integrity culture that aligns with the principles and norms of the ‘European Code of Conduct for Research Integrity’, and to counter research misconduct. The…

We aim to unravel the complex and intertwining regulatory systems that control development and antibiotic production in streptomycetes.

A tantalizing concept that has emerged in our recent research is binding kinetics. An important parameter is residence time (RT), a direct reflection of how long a drug stays bound to its target. This parameter is of crucial importance, because drug action lasts only as long as the receptor-ligand complex…

Disclaimer: Manuscripts related to the Resilience Center are for academic purposes only and are not intended for mass distribution or copying. Please refer to applicable laws for fair use, including copyright holders' restrictions on publications.

In the Criminal Justice research programme, (criminal) law researchers and social scientists – many of whom are criminologists – collaborate on various projects. The research programme focuses on the content and form of decisions that could be, should be and are taken in by actors in the criminal justice…

The deadline for applications is Wednesday 1 May 2024.

Leiden has a strong tradition in theoretical physics, thoroughly linked with experimental disciplines.

When you apply for admission, you’ll be asked to submit several documents.

You’ve been accepted! Leiden University looks forward to welcoming you as a new student. Your next step is to prepare for your studies. Below you can find some tips to help you get a head start as you embark on your studies at Leiden University.

The research group Organizational & Entrepreneurial Behavior investigates the behavior of individuals and groups who start, work in, or lead organizations, in order to inform organizational practice. By focusing on the behavior of (groups of) employees, entrepreneurs and leaders, the main levels of…

Division contact information & address

This research project from Leiden University looks at the opportunities and threats that flow from the existence of institutional and normative diversity in the area of fundamental rights for the effective protection of those rights in a pluralist world.

Key publications of the Cancer Drug Target Discovery group

How is the development of physiological responses to social evaluation in adolescence affected by other normative developments, such as pubertal, socio-cognitive and psychosocial development? Are social anxiety and public speaking anxiety associated with characteristic patterns of stress responses…

Improving healthcare with our scientific discoveries: that is the goal of pharmaceutical research at Leiden University. And there’s a lot involved in that. Our research starts with the discovery of the effect achieved by a particular substance, and sometimes continues all the way through to the development…

The BLRN members have published extensively in recent years. In addition to the BLRN book series, dissertations of BLRN members published in the E.M. Meijers Institute Series, you will find below a selection of our publications. For a more complete overview of publications of each BLRN member, please…

To develop a new generation of brain science (and train scientists) focused on explaining complex real-world behavioural patterns.

The major aim is to develop, evaluate, and implement disease-generic cognitive-behavioral interventions through the internet in order to optimize tailored health care for patients with chronic somatic conditions.