Anthropogenic noise has been shown to affect marine animals in various ways, this may have fitness consequences at individual and population level. This thesis aims to increase insight into the quantification of sound-induced behavioural responses that are relevant to fitness, and into factors that…

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

Develop a prototype combined chemical-microbial enzymatical process for the sustainable, green recycling and revalorization of polyamides and polystyrene

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.

Glycosidases are important enzymes in the turnover of polysaccharides and glycoconjugates, and are involved in a range of human pathologies including genetic disorders such as Gaucher and Pompe disease, but also in various cancers.

This project develops a scientific method to extract clinically relevant new information from patient forum websites that discuss patient experiences concerning e.g. medication, nutrition, co-morbidities, genetic factors etc.

The narrow but long stretched stript of Frisian land along the North Sea was already occupied before Roman times. However, man repeatedly suffered setbacks when he tried to extend his living space, both in the tidal marshes and the peat area south of them.

Promoter: J.G.E.M.Fraaije, Co-promotor: A. Kros

Ethiopian wolves are endangered diurnal Afroalpine rodent hunters. I investigated the interaction between wolves, rodents and human land use in Borena Sayint National Park (BSNP), Abune Yosef and Aboi Gara in Ethiopia.

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

This thesis describes biochemical investigations of glucocerebrosidase (GBA), the lysosomal β- glucosidase that is deficient in Gaucher disease (GD).

In this opinion article published in World Development, the authors present five research and policy priorities. While it is clear that ‘pluriversal’ designs need to guide the way forward (Kothari et al 2019), defining a set of key pillars can provide direction and purpose across this pluriversality.…

Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.

Una investigación definitiva sobre el nacionalismo que disecciona los patrones y las dinámicas que lo han convertido en un fenómeno mundial en auge.

Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.

The effects of anthropogenic noise on interactions between predators and their prey are still little understood.

Animal Sciences’ contributions to the Development & Disease research theme include the mechanisms and evolution of embryonic development, the development of cognitive mechanisms, and animal models for understanding mechanisms of human disease.

Since my master's thesis on the landed property of the Frisian monasteries in the Middle Ages I am highly interested in the do ut des-aspects of the relation between religious houses and the lay world. Key words here are: property, power, patronage and the role of religious institutions in the 'salvation…

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

Promotor: C.J. ten Cate, Co-promotor: H.W. Slabbekoorn

Does Artifical Light at Night (ALAN) disrupt seasonal physiological and behavioral patterns in migrating freshwater fish?

Spatial analysis on the basis of material culture has always been one of the major topics in archaeological research. Designating Place analyses the urban space of Roman Ostia and Pompeii in different ways, namely via geophysical analysis, spatial analysis, iconographic analysis and epigraphic analy…

The mycorrhizal symbiosis is among the most widespread species interactions on Earth⁠. This thesis focuses on orchid mycorrhiza, a unique mycorrhizal type that has caught scientists’ attention for centuries⁠.

In 'Dutch Atlantic Connections, 1680-1800', Gert Oostindie and Jessica V. Roitman, both of the Royal Netherlands Institute of Southeast Asian and Caribbean Studies (KITLV) and also affiliated with the History Institute of Leiden University, assemble an internationally acclaimed selection of authors,…

The name ‘Jambi flora’ refers to fossil plants found as part of a rock formation from the Early Permian (296 million years old), located in the Jambi Province of Sumatra, Indonesia.

Hermeneutics and the Humanities: Dialogues with Hans-Georg Gadamer / Hermeneutik und die Geisteswissenschaften: Im Dialog mit Hans-Georg Gadamer

Promotor: Prof.dr. G.R. de Snoo

CurveBend project aims to study the restauration of biodiversity in livestock landscapes through collective action, practical solutions, and research on ecological knowledge co-creation.

The research described in this thesis centered on retaining exo-β-glucosidases implicated in health and disease, in particular the human inherited lysosomal storage disorder, Gaucher disease (GD).

Promotor: Carel J. ten Cate, Co-Promotor: Hans W. Slabbekoorn

On February 7th, Lotte Dros-Hendriks succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Lotte on this great result.

Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…

Large carnivores and humans, along with their livestock, have co-existed for thousands of years. However, human population growth and an increase in economic activities are modifying the landscape for large carnivores and their prey.

Lecture

Transplantation of labial salivary glands to the eyelids for patients with dry eye appears to give excellent results clinically.

Large carnivore population is globally declining as a result of the fragmentation of habitat, large prey depletion and retaliatory killing by pastoralists.

Promotors: Prof.dr. G.R. de Snoo, Prof.dr. H. Leirs (Univ. Antwerpen), Co-promotor: H.H. de Iongh

Engineering an efficient microbial enzymatic polyethylene degradation pathway via an innovative combination of biochemistry and computational biology tools for enzyme discovery and characterization.

Interest groups play an important role in democratic society.

Although official law generally conceives of personal injury victims as individual rights holders, the actual experience of physical injury and its consequences is relational. Indeed, many researchers in the global North as well as the global South have contended that the very concept of the Self should…

Labour is back as a significant social and political force in Indonesia, as was shown in the recent 1 May trade union demonstrations in Jakarta. Over the past years major changes have taken place in Indonesian labour law, leading to new forms of judicial and political resolution of labour disputes.

ACPA offers students from both the Leiden University and the University of the Arts The Hague elective courses in visual art and music.

The ‘Koninklijke Hollandsche Maatschappij der Wetenschappen’, Royal Holland Society of Sciences and Humanities, has nominated Prof. Dr. Jaqueline Meulman as a member.

No fewer than seven Leiden FWN students received a Young Talent Award from the Royal Dutch Academy of Sciences on Monday, 29 November. Mark van den Bosch and Karlijn Kruiswijk won a graduation prize, a group of young astronomers won the ET Outreach Award and the other five students each received an…

The KNVI (Koninklijke Nederlandse Vereniging van Informatieprofessionals) awarded Thesis Prizes for Informatics and Information Science

An astonishing twelve students from Leiden University have received a Young Talent Award from the Royal Holland Society of Sciences and Humanities in Haarlem, a record. During the festive ceremony on 25 November, five master students received a Young Talent Graduation Award for their thesis and seven…

S.S. Kolipaka’s thesis questions and investigates the survival prospects of reintroduced tigers and their offspring’s in the human dominated landscape of Panna tiger reserve in India.

Promotor: J.G.E.M.Fraaije, Co-promotor: A. Kros