The ideas underlying this thesis are that lipidomics may improve the diagnosis of liver metabolic diseases, and can provide further insights into the underlying pathophysiology of these diseases.

In this dissertation Itandehui Jansen examines the ‘Voice’ of the filmmaker from a political and aesthetic perspective.

Stephen Moore defended his thesis on 26 May 2020.

In this article, Sophie Vériter examines the EU’s unprecedented ban on Russian state media following the invasion of Ukraine, using securitisation theory

This report highlights the huge potential of public inquiries to ensure that lessons are learned from COVID-19 to help the UK prepare for a future pandemic.

This book is a first comparative study of the Nuni dialects.

How do laws and procedures for police vetting unfold in practice?

Promotor: Prof.dr. S.F. Portegies Zwart

An objective of this research was to achieve direct, well-defined and non-rate-limiting electron transfer between respiratory enzymes and the electrode surface by means of 'Q-wires'.

The second and final report on the Netherlands‘ crime-terror nexus has analysed all fourteen profiles of individuals arrested in 2015 for offences of terrorism.

This thesis focuses on the design and synthesis of activity-based probes and inhibitors targeting enzymes involved in the degradation of specific plant glycans.

The RNA guided endonuclease based on the CRISPR/Cas system of Streptococcus pyogenus is a potent new tool for genome engineering in plants.

In 2019, Aliaksandr Lukashenka marks a quarter of a century as the first, and so far only president of the Republic of Belarus. This new book by Dr. Matthew Frear, Assistant Professor of Russian and Eurasian Studies, offers the most up-to-date analysis of government and politics in a country usually…

On 10 October 2018, Richard Resch defended his doctoral thesis 'The Interpretation of Plurilingual Tax Treaties'. The doctoral research was supervised by Prof. mr. C. van Raad.

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. D. Tibboel (EMC, R’dam)

Nature and History, Towards a Hermeneutic Philospohy of Historiography of Science

The Corfu Papers

Policy Note Insecurity in Burkina Faso – beyond conflict minerals: The complex links between artisanal gold mining and violence

Reinforcement learning is a framework that enables agents to learn in a manner similar to humans, i.e. through trial and error. Ideally, we would like to train a generalist agent capable of performing multiple tasks and achieving various goals.

Explaining cutback management strategies in public sector organisations: change leadership in times of crisis. How does the publicness of organisations affect the choice and implementation of cutback management strategies?

This research note argues that the “lone wolf” typology should be fundamentally reconsidered.

The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.

Western thought has often dismissed shadows as fictional, but what if fictions reveal original truths?

The United Kingdom’s relationship with the European Union was supposed to be definitively settled several times during the past decade – yet it was not. The 2016 referendum brought about a surge in interest in legal questions, especially of EU law and international economic law. This presented scholars…

Promotor: J.N. Kok, Co-promotor: H.J. Hoogeboom

Promotor: Prof.dr. B. van de Water, Co-promotor: E.H.J. Danen

FSW building, Wassenaarseweg 52, 2333 AK, Leiden

Essays in archaeology, ethnohistory and ethnography of the Amerindian circum-Caribbean

The aim of current study was to develop a dried inactivated polio vaccine (IPV) formulation with minimal loss during the drying process and improved stability when compared with the conventional liquid IPV.

On 14 May 2020, Pieter Rustenburg defended his thesis 'Een algemene normtheorie toegepast op open normen in het belastingrecht'. The doctoral research was supervised by Prof. A.O. Lubbers and Prof. J.L.M. Gribnau.

Cultural Anthropologist Erik de Maaker published, together with Monica Janoswki (School of Oriental and African Studies, University of London), Stories across Borders: Myths of Origin and Their Contestation in the Borderlands of South and Southeast Asia in Southeast Asian Studies (SEAS).

Beyond Empires explores the complexity of empire building from the point of view of self-organized networks, rather than from the point of view of the central state.

This dissertation assesses the influence of British Celtic on the phonological development of English during and shortly after the Anglo-Saxon settlement period, ca. AD 450-700.

In this article in 'The Senses and Society' Jasmijn Rana discusses how women learn to move, use their bodies, and become a different kind of being than men. She focuses on the embodiment of gender in recreational running environments.

The Early Upper Palaeolithic (EUP) record throughout Europe is characterized by major changes in human behaviour.

This paper written by Alexandre Afonso, Assistant Professor and Researcher at Leiden University, argues that gender norms and the political strength of the left were important structuring factors regarding why European countries choose migrant labour to expand their labour force in the decades that…

The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…

Aluminium-based adjuvants, such as aluminium hydroxide and aluminium phosphate, are well-known for their immune-stimulating properties.

Promotor: A. Doelman, Co-promotores: P.J.A. van Heijster; A. Zagaris

This thesis mainly focuses on cross-modal retrieval and single-modal image retrieval via deep learning methods, i.e. by using deep convolutional neural networks.

Despite being the second largest transmembrane protein family after GPCRs, the SLC superfamily has only gained significant attention in early drug development over the past decade.

Autopaghy is an intracellular degradation system which targets cytosolic components to lytic compartments for degradation and recycling of the building blocks of the cell.

The experiences of ethnic ‘Other’ females have – until recently – been widely overlooked in the study of sport. There continues to be a need to produce critical scholarship about ethnic 'Other' girls and women in sport and physical culture, in order to represent their complex, multifarious and dynamic…

When a star is born in our Galaxy, it is quite likely that it has formed within a massive cluster, which hosts numerous high-mass stars bathing their lower mass neighbours in UV radiation.

Does the δ-machine have higher accuracy than the other feature-based classifiers in some conditions?

In this article, Adriana Cerdeira and Dovile Rimkute explore how certain dynamics shape banks' behaviour.

There are a number of problems in philosophy that seem to share a similar possible solution: 'Why do promises and contracts bind?', 'Why ought citizens and judges obey the law?' and 'Can we realize the gains to be made from cooperation?'. All three problems (as well as some others) share a possible…

Source: J Med Chem, Volume 57, Issue 8, pp. 3213-22 (2014)

KNOWMAK project aims at developing a web-based tool, which provides interactive visualisations and state-of-the-art indicators on knowledge co-creation in the European Research Area (ERA).

Stratigraphy, Palaeoenvironment and Archaeology of the Middle and Late Pleistocene Deposits.