In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

In the studies described in this study, we introduce a novel ex vivo human skin barrier repair model. To develop this, we removed the upper layer of the skin, the stratum corneum (SC) by a reproducible cyanoacrylate stripping technique.

An archaeological case-study of the Pointe des Châteaux, La Désirade and Les Îles de la Petite Terre micro-region, Guadeloupe, F.W.I.

This thesis investigated miniaturized mass spectrometry (MS)-based analytical methods to address challenges in analyzing biomass-restricted biological samples.

This article by Honorata Mazepus and Florian van Leeuwen in the journal Governance: An International Journal of Policy, Administration and Institutions looks at how evaluations of authorities were influenced by four aspects of a governmental response to a hypothetical disaster.

How do Humanitarian Response Organizations (HROs) and Virtual & Technical Communities (V&TCs) collaboratively govern disaster sensemaking processes, and what challenges shape the effectiveness of these collaborations between 2010 and 2016?

Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…

In this project we study the properties of statistical- and rule-learning mechanisms in relation to the acquisition and evolution of language. We ask to what extent these mechanisms are unique to humans - or to human language - by comparing the acquisition of vocal structure in two species: humans (infants)…

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

Of all the mass in our Universe, 80% is thought to consist of a hypothetical and invisible substance called dark matter (DM).

This paper describes two synthetic lipid models designed to replace human stratum corneum (SC) in studies of the impact of volatile organic chemicals on the molecular organization of the skin barrier lipids.

The endocannabinoid receptors CB1R and CB2R are involved in a plethora of processes, and consequently are involved in many pathological conditions. Their wide distribution makes the CBRs both an interesting therapeutic target and hard to study.

Spectroscopic studies on fluorescent single molecules in organic condensed matter does not only provide information about the molecule itself, but also its near environment. By suppression of phonon-induced broadening of spectral lines through cooling to low temperatures, small changes in the spectral…

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

β-Lactamases are enzymes that can break down β-lactam substrates, such as antibiotics, preventing the use of these antibiotics for the treatment of various infectious diseases. However, some compounds, β-lactamase inhibitors, can block these enzymes allowing for possible treatments using a combination…

Structure-affinity relationship (SAR) and structure-kinetics relationship (SKR) studies were combined to investigate a series of biphenyl anthranilic acid agonists for the HCA2 receptor.

This dissertation defends the existence of a type of movement that has so far been considered not to be possible, namely, movement of a bare head to a specifier position over arbitrarily long distances.

The urban graveyard presents several studies in which the results of older archaeological and osteoarchaeological research are compared to more recent excavation data from several Dutch, Belgian and Danish cities and towns.

Organised in four separate sessions throughout the day, and broadcast live online to guests and families who could not join, a total of 260 students received their Bachelor’s Diploma of International Studies on 28 August 2020 at the graduation ceremony in the historic Pieterskerk in Leiden.

On Tuesday 3 September 2024 Straton Papagianneas successfully defended a doctoral thesis and graduated.

On Friday 22 November 2024 Ye Jiang successfully defended a doctoral thesis and graduated.

The brain structure of young people with conduct disorder differs significantly from that of their typically developing peers. This is the conclusion of an international study that analysed more than two thousand MRI scans, recently published in The Lancet Psychiatry. Dr Moji Aghajani, one of the principal…

Many of our staff and students have won prizes over the past year. Others have been awarded a subsidy, or, because of their eminence in their field, they have been appointed member of an academic society or have taken on a position in the community. Reasons enough to be proud of them and to include…

This study aims to examine how South Korea (hereafter, Korea) and Japan, two neighboring countries in Northeast Asia, have been responding to and mitigating the spread of COVID-19.

At the request of Dutch Parliament, Professor of European Law, Freya Baetens, wrote an expert case study on the EU-Canada Free Trade Agreement (CETA) and the EU-Indonesia Free Trade Agreement (CEPA-Indonesia). This factsheet offers parliamentarians clear, research-based insights into complex policy…

The Security Studies bachelor's programme has received a bronze medal in EW Best Studies 2023. Every year, EW Best Studies selects the top programmes in Dutch higher education.

Organised in three separate sessions throughout the day, and broadcast live online to guests and families who could not join, over 200 students received their Bachelor’s Diploma of International Studies on 3 September 2021 at the graduation ceremony in the historic Pieterskerk in Leiden.

On Friday 16 May Juul Eijk successfully defended a doctoral thesis and graduated.

A child who receives fewer nutrients in the womb than their identical twin brother or sister is more likely to have developmental problems later in life. This is what researchers from the Leiden University Medical Center (LUMC) write in The Lancet Child & Adolescent Health. This study shows that unfavourable…

More than a hundred people took part in the conference on Studying with a Disability on 20 April. Dozens of students shared their experiences. 'I would rather you ask me the same question a hundred times than that you decide on my behalf.'

This research aims to investigate how different social forces interact with hydropolitics in the Eastern Nile Basin and what are the constraints of engagement.

Understanding others’ emotional behavior is essential for navigating daily social life. But how is such an understanding achieved? The eye-tracking study by Yung-Ting Tsou and colleagues shows that children with hearing loss adopt a unique visual strategy that makes uses of explicit visual information…

Promotor: Prof.dr. T. Schmidt, Co-Promotor: Dr. ir. S.J.T. van Noort

Author Gustaaf Peek, who has been nominated for the Libris Literature Award, studied English Language and Literature in Leiden. ‘I completely submersed myself in literature during my studies, and the effects are still with me today.'

We investigate the molecular basis underlying health and disease and provide answers to existing and emerging health problems. Within this theme, we study diseases ranging from rare genetic disorders to cancer and infectious diseases. We make use of a wide variety of model systems and pursue diverse…

On Tuesday 14 January 2025 Milan Ismangil successfully defended a doctoral thesis and graduated.

Are you keen to immerse yourself in a new culture, broaden your horizons and make friends for life? If so, come to the Study Abroad Festival on Friday afternoon 14 October.

On Wednesday, September 17, 2025, Prof.dr. Sarah Cramsey convened a book manuscript event at the beach of Wassenaar near Leiden to discuss her new book 'Caring through Catastrophe: Jewish Children and their Caretakers during the Holocaust' which is under contract with Indiana University Press.

Mapping sanitary infrastructure in large urban societies in the Low Countries, 1200–1900

On 12 December 2019, Dr Yannick van den Brink, assistant professor at the Department of Child Law and Rubicon Research Fellow at the University of Cambridge, gave a keynote speech at the conference ‘Strengthening Juvenile Justice Systems in Europe’, which was organised in Valencia, Spain.

When Henriëtte Hoffman was ten years old she was enthralled by The Last Emperor, a 1987 film about the twelfth and last emperor of the Manchu dynasty. It was an interest that eventually led to a five-month stay in Chengde in China for her Asian Studies research master’s programme. During her time in…

It may seem as though adolescents do as they please, but they are more sensitive to their parents’ opinions than they would appear. The adolescent brain reacts strongly to parental criticism or praise. These are the results of a study by an interdisciplinary research group of psychologists and neuroscientists…

NETHATE is a Marie Skłodowska-Curie Actions (MSCA) project seeking to investigate the roots, societal impact and mitigation strategies of hate in offline and online foras.