1,778 search results for “molecular biology” in the Public website
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Collaborating bacteria sacrifice themselves for the greater good
Like ants, termites and bees, some bacteria work together as a multicellular group. There is a strict division of labour in such colonies, to make the group more resilient to the outside world. Now researchers have found that some parts of the bacterial colony can take ‘for the greater good’ to a whole…
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Why fundamental science matters
Why do we need fundamental science? For a lot of reasons, speakers showed at the Lustrum Symposium ‘Science Matters’. This symposium was held on 18 March 2016 to celebrate the 200th anniversary of the Faculty of Science.
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Learning together about electron microscopy
Chinese and Leiden scientists came together in Leiden to study the intricacies of modern visual techniques.
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Sander van Kasteren: from molecule builder to Professor of Chemical Immunology
Sander van Kasteren only noticed some small, subtle changes since he was appointed professor on 1 May. Still, he has to get used to the idea, even though he had been working towards the professorship for a few years. ‘I don't quite see myself as a professor yet.'
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Three awarded research projects in NWO-XS call
Cryogenic memories, antibiotic treatment for urinary tract infections and recycling plastic sustainably. These are the subjects of the three NWO-XS grants awarded to Leiden Science researchers.
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Improving therapeutic vaccines
Chemist Sander van Kasteren aims to accurately map how our immune system responds to vaccines, particularly those aimed at curing diseases like cancer and chronic viral infections. The goal is to use this knowledge to improve vaccine design. An ERC Consolidation Grant will provide him with the funding…
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Ad IJzerman wins prestigious Nauta Pharmacochemistry Award
Professor of Pharmacochemistry Ad IJzerman has won the Nauta Award for his years of research into signal processing proteins that are interesting for the development of new medications: G protein coupled receptors. The prize is awarded every two years for services to pharmacochemistry and chemical b…
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A unique defence: Bacteria lose cell wall in the presence of virus
Bacteria temporarily live without their cell wall if dangerous viruses are near. A remarkable feature, as the cell wall is a sturdy barrier against threats. Still, the discovery has a logical explanation ánd might be of a consequence for fighting pathogenic bacteria, according to Véronique Ongenae,…
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Non-invasive DNA-labeling tool opens doors for new research
Dutch researchers have developed a new tool to label DNA for studying chromosomes in live cells. The tool is non-invasive and can be applied in culture but also in living organisms, such as zebrafish embryos. The team published their findings in the journal Nucleic Acids Research.
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Medical Delta AI for Computational Life Sciences
The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?
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Leiden researchers depict the formation of galaxies
An international team of astronomers, with researchers at Leiden Observatory playing a leading role, has mapped the fuel for galaxy formation in the iconic Hubble Ultra Deep Field. The results of the research have been accepted for publication in The Astrophysical Journal.
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Freon-40 may not be a useful marker of life
Observations made with the ALMA telescope in Chile and ESA’s Rosetta mission, have detected the faint molecular fingerprint of methyl chloride in gas, a chemical commonly produced by industrial biological processes on Earth, around both an infant star and a comet. Methyl chloride, also known as Freon-40,…
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Foraging skills may have made the essential difference in the evolution of our huge brain
Hunter-gatherers acquire their food through complex gender-specific foraging techniques for a relatively stable and diverse supply of energy. New research indicates that this specialisation by boys and girls starts at a very young age. Most likely, this enabled the human species to evolve much larger…
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Faculty of Science starts new year with awards for talents
Mathematician Robbin Bastiaansen, physicist Irene Battisti, pharmacist Fouzia Lghoul-Oulad Saïd and physics and astronomy student Maite Boden are the winners of the annual prizes of the Faculty of Science. Boden was honoured as the first Young Star, a new prize for the best bachelor’s student of the…
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Three Leiden Science projects receive computing time on national supercomputers
A night sky of more than 40 petabytes in size, simulating young star clusters and understanding how the body inhibits viruses: three Leiden projects have received computing time on one of the national computer systems.
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Unravelling prehistoric fire use: ‘Variation in fire conditions equals variation in human behaviour’
Building a fire involves many variables, such as size, choice of fuel, temperature, and burn time, that affect the way the generated heat can be used, and therefore the potential function of a fire. A group of Leiden archaeologists are, together with a team of international colleagues, investigating…
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First detailed picture of ice in planet-forming disk
An international team of astronomers led by Ardjan Sturm of the Observatory has made the first two-dimensional inventory of ice in a planet-forming disk of dust and gas surrounding a young star. The researches, including Melissa McClure, used the James Webb Space Telescope and publish their findings…
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Photosynthesis works with valves
Photosynthesis is the origin of life on earth, but it is a phenomenon that is still barely understood. Take, for example, the extremely efficient mechanism of electron transport. Leiden researchers demonstrate for the first time where one particular cause of this might be found.
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‘Take medicine target saturation into account’
Not taking into account the saturation of drug targets can lead to wrong conclusions about the duration of a drug's action. This is what former PhD candidate Wilbert de Witte writes together with the Leiden professors of pharmacology Meindert Danhof, Piet van der Graaf, and Liesbeth de Lange in Nature…
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Glycine in space produced by dark chemistry
An international team of laboratory astrophysicists and astrochemical modellers has shown that glycine, the simplest amino acid and an important building block of life, can form under the harsh conditions that govern chemistry in space. The results have been published this week in Nature Astronomy and…
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Ewine van Dishoeck goes stargazing
From the birth of the universe to the molecules in a planet's atmosphere. The first five pictures from the James Webb Space Telescope (JWST) show the enormous range in which the space telescope can operate. Ewine van Dishoeck, professor of molecular astrophysics, took a look at the first images Tuesday…
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Celestial worlds and comet hysteria in Van Dishoeck exhibition
A moon rock from the Apollo 17 mission, antique globes and the cosmos according to Wassily Kandinsky. Ewine van Dishoeck, Professor of Molecular Astrophysics, has put together an impressive exhibition at Rijksmuseum Boerhaave.
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Flu stops when you block the enzyme that cleaves off virus particles
A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.
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ERC Advanced Grants for four Leiden researchers
From a new generation of antibiotics and more-effective vaccines to a map of dark matter and new light on Hindu traditions. Four researchers from Leiden University have received a prestigious €2.5m ERC Advanced Grant to develop their research.
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Is Michael Meijer the Smartest Chemist of the Netherlands?
He is occupied with the home stretch of his promotion. But in between, there is another challenge: Michael Meijer is going through to the finals of ‘The Smartest Chemist of the Netherlands’. On Tuesday 9 October, he and five others fight for this title during the Evening of Chemistry. ‘I was dragged…
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Versatile antiviral proteins discovered with supercomputer
A single tiny molecule that can destroy flu, corona, HIV and Zika viruses? Yes, it really does exist. Biophysicist Niek van Hilten, who will receive his doctorate on 14 September, contributed to this discovery.
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Assessing the safety of chemicals and medicines without laboratory animals
One of the holy grails of drug research is to be able to assess the safety of chemicals and pharmaceuticals without using laboratory animals. Researchers from Leiden University, among others, now receive a grant from the National Science Agenda to pursue that goal.
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Leiden scientists develop topological barcodes for folded molecules
The team of Alireza Mashaghi at the Leiden Academic Centre for Drug Research has found a way to determine and classify the shape of proteins. Their new theory defines the topology of proteins as a simple and precise barcode that allows the identification of all types of folds. ‘This barcode enables…
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New potential cancer drugs and where to find them
Cancer research generates massive amounts of data, but traditional tools often fail to fully harness their potential. How can we unlock this data to provide better treatments for cancer patients? PhD candidate Marina Gorostiola González explored this by using advanced data analysis techniques to guide…
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Two-pronged attack on infectious diseases
A combination of two potential drugs gives hope of a 'super blockage' of an over-active immune system, Leiden researchers report in Nature. The breakthrough came from the crystallisation of a membrane protein.
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Ronald Stark and Amina Helmi join the management of NOVA
The directorate of the Netherlands Research School for Astronomy (NOVA) has two new members. Ronald Stark (currently at NWO) will be the new Executive Director of NOVA from 1 September. Amina Helmi (Professor of Dynamics, structure and formation of the Milky Way at the University of Groningen) will…
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Ewine van Dishoeck after pontifical appointment: ‘Science and religion can coexist’
Pope Francis has appointed astronomer Ewine van Dishoeck to the Pontifical Academy of Sciences. She joins an illustrious list of Nobel Prize winners, such as Ernest Rutherford, Max Planck, Niels Bohr and Erwin Schrödinger. What is her view on this? An interview with our professor of Molecular astrop…
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Stephan Hacker elected into the board of Assistant Professor Network Netherlands
Dr. Stephan Hacker, an assistant professor in the department of Molecular Physiology at the Leiden Institute of Chemistry of Leiden University has been elected secretary of the board of APNet, the Assistant Professor Network Netherlands. Hacker will take a leading role in the young network organisation…
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Young stars in the Orion Nebula are practicing birth control
Astronomers from Leiden University have discovered that the star wind from a newborn star in the Orion Nebula prevents more stars from forming in the immediate vicinity. They made the discovery with data from the SOFIA observatory. This was announced by co-author Xander Tielens during a press conference…
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Student team hopes to heal skin with squid protein
Eleven ambitious Leiden students hope to heal burns with a special substance from squid teeth. They are taking part in the international iGEM competition. They need to raise almost 10,000 euros to fund their project this summer.
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Examining DNA molecules one by one: how combining techniques can help us understand diseases such as dementia
‘By cleverly combining new techniques for analysing DNA at the level of individual molecules, we can achieve real breakthroughs in research into conditions such as dementia,’ predicts Professor John van Noort. Together with four leading biophysics research groups, he has written a review article in…
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New SPARXS technique reveals DNA behaviour at unprecedented speed
Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process. Biophysicists from Delft University of Technology and Leiden University developed a technique that speeds up screening…
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Leiden University more sustainable by the day
10 October is the Day of Sustainability. What is the current status of sustainability at Leiden University? Things are moving ahead. Professor of Environmental Biology and Dean of the Faculty of Science, Geert de Snoo, outlines a new prospect: biodiversity.
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Bacteria inside plant roots battle fungal disease
Two bacterial species team up inside the plant root system to rescue their host from fungal infection. This was discovered by a team of microbiologists and bioinformaticians from the Netherlands Institute of Ecology, Wageningen University, and the Institute of Biology Leiden. They also identified the…
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Halting protein degradation may contribute to new cancer treatment
Chemist Gerjan de Bruin has designed a method of slowing down the degradation process of proteins in cells. This may contribute to new cancer medicines with fewer side-effects. PhD defence on 1 June.
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Vici grants for three Leiden researchers
Three Leiden researchers will each receive a Vici grant of 1.5m euros. They are historian Cátia Antunes, cell biologist Dennis Claessen and archaeologist Marie Soressi. This grant from the Dutch Research Council (NWO) will give them the opportunity to form their own research group over the next five…
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Leiden City of Science 2022: preparations are in full swing!
In 2022, Leiden will be the European Capital of Science. An enthusiastic team from our Faculty is already busy planning the activities. Today we speak with Marin Visscher. As a project coordinator, he seeks the connection between university and society.
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Going accurate for molecule – metal surface interactions
Researchers from the THEOR CHEM group at Leiden University strive to set new benchmarks in the accuracy of the prediction of interaction energies between molecules and metal surfaces.
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Four ERC grants for Leiden researchers
Four Leiden researchers have each been awarded a consolidator grant of up to 2 million euros by the European Research Council (ERC). They carry out research on a diverse range of subjects, from gender stereotyping in the field of science to making sugar molecules.
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Festive celebration International Day of Women and Girls in Science in Leiden
On Saturday 9 February 2019 we celebrated the International Day of Women and Girls in Science 2019 in Leiden! View the photos of this festive day, with contributions from Robbert Dijkgraaf and Ewine van Dishoeck, and numerous fascinating workshops and exciting experiments.
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Eveline Crone to receive Ammodo KNAW Award
Professor of Neurocognitive Developmental Psychology Eveline Crone will receive an Ammodo KNAW Award. This was announced by Ammodo, an institute for arts and sciences, and the Netherlands Academy of Arts and Sciences (KNAW) on 25 January.
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Spinoza and Stevin prizes for LUMC professors
Sjaak Neefjes, professor of Chemical Immunology at the LUMC, has been awarded a Spinoza prize of 2.5 million euros. His colleague Ton Schumacher, professor of Immunotechnology affiliated with Leiden University, the LUMC and the Antoni van Leeuwenhoek cancer centre, has been awarded the Stevin prize,…
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Stefano Coppola Receives AXA RF Fellowship to Study Pancreatic Cancer
Leiden biophysicist Stefano Coppola has received the prestigious AXA Research Fund postdoctoral fellowship. With this grant he can work for two years on a project to research the role of mechanical factors in the development of pancreatic cancer.
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NGL presents: biweekly lectures on Corona
The Natuurwetenschappelijk Gezelschap Leiden (Leiden Science Society) is organising short online evening lectures, every two weeks on Thursday, held by a Leiden scientist who will talk about an aspect of the Corona crisis from their expert point of view. NGL members, alumni, (former) employees, students…
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Building molecules with sustainable energy
The E2CB programme has been launched to bring CO2 emissions to zero by 2050. The goal: to produce all raw materials for the chemical industry from sustainable sources. Professor of Electrochemistry Marc Koper is involved in the project.
