The CC chemokine receptor 2 (CCR2), a member of the G protein-coupled receptor (GPCR) superfamily, is widely involved in autoimmune and inflammatory diseases. However, no drugs for this receptor have made it to the pharmaceutical market yet.

A part of the steel construction of the former Gorlaeus high-rise forms the basis of a new green bike park which is part of the redevelopment of the Faculty of Science.

On the 28th of June, Laura Smorenburg successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Laura on this achievement!

Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…

Is online radicalisation is an analytically useful concept when discussing contemporary cases of terrorism?

We consider the propagation of electrical signals through nerve fibres.

Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.

This book provides a grammatical sketch, glossed texts and a glossary of Tarifiyt Berber, which is the main heritage language of the Moroccan community in the Netherlands, Belgium and Germany.

On the 24th of June, Martijn Wackers successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Martijn on this achievement!

The debate in Europe about digital sovereignty, technological sovereignty, data sovereignty and strategic autonomy has been building over recent years at both the EU level and the level of individual Member States. The different concepts – and their diverse interpretations – cover the sovereignty concerns…

Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.

Ömer Gürlesin defended his thesis on 28 November 2018

Artful Mathematics: The Heritage of M. C. Escher

How does the design of online participation platforms influence the inclusivity of online direct participation?

This book brings together new research on the practices of newsmaking.

A political-legal study of rights invocation by pollution victims in China and Indonesia

Nowadays, it is well known that hydrogen and helium (and small traces of lithium and beryllium) were created shortly after the Big Bang, while the heavier elements are created in the cores of stars at different evolutionary stages. When these stars explode as supernovae, they expel metals synthesised…

This book explores the boundaries of the category of gender and their theoretical significance within the framework of Canonical Typology.

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Promotor: H.J.A. Röttgering, Co-promotor: M. Haverkorn

This thesis explored the question whether Scrum methodology might function as an appropriate scaffold to enhance students’ learning and to support teachers in context-based secondary chemistry education.

This procedure is relevant for contract and external PhD candidates only.

An experimental approach to organic palaeolithic technology

Promotor: Prof.dr. J. Kuiper, Co-Promotor: S.C.A. de Jager

Promotores: T.H.W. Bäck, Y. Tan, Co-promotor: M.T.M. Emmerich

This book offers a comprehensive and accessible introduction to a novel theory of syntax, which analyzes grammar from a semantic perspective.

This article examines how the threat of terrorism has been addressed at the policy level through an analysis of a specific case in Mali.

In the Psychology Lab on Wheels, we conduct innovative research together with citizens. We drive our mobile lab to people all over the country helping to bridge the gap between science and society.

This book analyses the expulsion of delinquent foreigners and their exclusion from the territory through a comparative lens.

Proteases degrade matrix molecules in the atherosclerotic plaque, thereby reducing atherosclerotic plaque stability. Mast cells, that contain proteases such as tryptase and chymase, have been identified at the site of rupture in specimens of human coronary arteries and their number in the plaque was…

Aviation safety is of global concern. Yet 43% of countries worldwide lack the expertise and administrative capacity to ensure effective safety oversight of the aviation activities for which they are responsible under international law.

The Co-Align Conference 2023 will be held on 16 May 2023 at Leiden University.

To what extent have the Dutch and British militaries learned from their counterinsurgency operations in southern Afghanistan between 2006 and 2020?

Promotors: C.A.J. Knibbe, Anthonius de Boer, Co-promotor: M.M.J. van der Vorst

What is the current relevance of the ethics of counterterrorism and what is the added value of ethics support within the practice of counterterrorism?

The aim of this research project was to increase understanding of which collaborative learning approaches already exist in conservatoire education, and how implementation of collaborative learning could be supported.

Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.

How do European Muslim men and women become involved in a violent jihadist struggle abroad?

The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.

Low-mass main-sequence stars like our Sun are continuous sources of outflowing hot magnetised plasma. In the case of the Sun, this is known as the solar wind, whereas for other stars they are called stellar winds.

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

The position of writing within the domain of artistic academic research is not self-evident. In academia, standard practice is to use writing for the transfer of knowledge: it is a means of communication. In the practice of (nonlinguistic) artistic research, the outcome is also often contextualized…

On the 16th of February, Yunus Sulistyono successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Yunus on this achievement!

My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.

Promotor: Prof.dr. W.J.G.M. Peijnenburg, Co-promotor: Dr. ing. M.G. Vijver

Benjamin Marius Telders, professor of international law, died of typhus in Bergen-Belsen on 6 April 1945. He was an example of civil courage before and during the occupation. He spoke up against inequity and injustice.

This dissertation is an experimental study of laser-generated, atmospheric pressure, transient toroidal helium plasmas.

From 1550 onwards, a great interest in the natural world developed across Europe. This interest was not only stimulated by a growing knowledge of local flora and fauna, but also by the import of numerous exotic animal and plant species. Think, for instance, of researches and collectors like Gessner…

On 10 March 2021, Pieter Huizing defended his thesis 'Parallel Enforcement of International Cartels and Its Impact on the Proportionality of Overall Punishment'. The doctoral thesis was supervised by Prof. T.R. Ottervanger.