Mapping of bacterial genomes to combat infectious diseases

From 22 to 24 October, researchers of the MARBLES-project informed museum visitors about microbes: bacteria and fungi that live all around us. The event was organised around the Micro-day of Leiden, which is this year’s EU City of Science.

On 1 March, Lennart Schada von Borzyskowski will start on a tenure track position at the Institute of Biology Leiden (IBL). With a focus on the natural and synthetic biochemistry of environmental bacteria, he wants to apply their features to health and sustainability issues.

Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.

A bacterium hiding from the immune system and picking up bits of DNA from its environment. The result: gaining new traits, such as better protection against antibiotics. Fortunately, we have not found such a damning scenario yet. However, PhD student Renée Kapteijn did find the first clues, which…

Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…

PhD defence

PhD defence

PhD defence

BRAIN Biotech and the Leiden University will jointly develop an Aspergillus based production strain with high yield and thus contribute to a bio-based circular economy. The cooperation is based on BRAIN´s molecular tool BEC.

The Dick Stufkens Prize 2021 for the best PhD thesis of the Holland Research School of Molecular Chemistry (HRSMC) has been awarded to Klaas van Leest for his thesis 'Open- Shell Cobalt Complexes with Redox-Active Ligands; Electronic Structure and Nitrene Transfer Reactivity'. Van Leest, who is now…

The Royal Netherlands Academy of Arts and Sciences (KNAW) selects prominent researchers as members based on their scientific achievements. On September 17th, the KNAW will install 21 new members, including Leiden physicist Michel Orrit and chemist Hermen Overkleeft.

Researchers led by Professor of Chemistry Marcellus Ubbink have recently published a study in Proceedings of the National Academy of Sciences (PNAS) about the dynamics of an important redox enzyme. This work was accomplished thanks to an NWO VICI subsidy granted to Professor Ubbink.

Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…

Sustainable rose smell that can be produced on a large scale. Tobias Fecker made this into a possibility during his master's thesis, which was a collaboration between the IBL and the TU Delft. He wins the fourth edition of the Krijn Rietveld Memorial Innovation Award.

Leiden chemists Marc Koper and Ian McCrum have discovered that the degree to which a metal binds to the oxygen atom of water is decisive for how well the chemical conversion of water to molecular hydrogen takes place. This insight helps to develop better catalysts for the production of sustainable hydrogen,…

Yuvraj Birdja converted CO2 to formic acid to store energy in a sustainable way, with different catalysts. With this new knowledge, scientists are a step closer in industrially converting CO2 to chemicals and fuels. This can help reduce CO2 emission and the greenhouse effect.

The Fritz Zwicky Prize 2022 for Astrophysics & Cosmology has been awarded to Prof. Ewine F. van Dishoeck for her pioneering, decades-long work in astrochemistry and molecular spectroscopy, as well as for her leadership within the astronomical community. The award was announced today by the European…

Fijs van Leeuwen, Professor of Radiology, Molecular Imaging and Image-Guided Therapy, advocates an open and respectful academic culture that always puts the patient first. He delivered his inaugural lecture on 13 November.

Endocannabinoids - the body's own marijuana - are promising departure points for drug research. Professor of Molecular Physiology Mario van der Stelt examines whether inhibiting their production can be a way to fight inflammatory brain disease and to combat obesity. Inaugural lecture 19 October.

Researchers at Leiden University led by Mario van der Stelt (Leiden Institute for Chemistry) have set ‘gold standards’ for developing new painkillers based on the medicinal effects of cannabis. Publication in Nature Communications.

Plant scientist Omid Karami is the first winner of the Krijn Rietveld Memorial Innovation Award. The jury praises the outstanding quality of his scientific research as well as the positive societal impact and commercial potential of his work.

Bacteria found in soil specialise in the colony by division of labour. Some of the bacteria produce antibiotics, even when it comes at the expense of their individual reproduction success, to defend their colony against competitors. Publication in Science Advances.

Bacteria carry countless hidden treasures in their DNA: fragments that could hold the key to new medicines. But how do you pick out the most promising ones from millions of options? ‘Look at the switches that turn genes on and off,’ says molecular biologist Gilles van Wezel.

An astonishing twelve students from Leiden University have received a Young Talent Award from the Royal Holland Society of Sciences and Humanities in Haarlem, a record. During the festive ceremony on 25 November, five master students received a Young Talent Graduation Award for their thesis and seven…

Marc Koper has been selected as one of the six new fellows in 2015 of the International Society of Electrochemistry.

In what settings do great ideas turn op? Quanta Magazine follows top scientists to their favorite places to think, tinker and create. Leiden astronomer Ewine van Dischoeck showed the magazine the Noordwijk beach. 'Somebody from the Netherlands is unavoidably linked with water.'

The Stans Prize is a yearly student incentive award for the best thesis, article or report produced by a CML student. Jim van Ruijven wrote his report for his bachelor study in Sustainable Molecular Science and Technology.