Source: Br. J. Pharmacol., Volume 172, Issue 3, pp. 940-55 (2015)

The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.

The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets

PACES is an innovative, inter-disciplinary and multi-level research project that asks, How do changes in society, individual life experiences and migration policy shape decisions to stay or to migrate over time and across countries? And how can this knowledge inform future migration policies and gov…

Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.

Long-distance Trade in Early Medieval Landscapes (ca. 6th-12th centuries)

Microglia support the central and peripheral nervous system by forming the first line of defense against hazardous events. Microglia are increasingly acknowledged as critical players in neurodegenerative diseases, highlighting them as potential therapeutic targets.

How can the legal and socio-legal research skills of Indonesian jurists be increased in order to promote legal certainty and to strengthen the capacity of the judicial training in the country?

The master's specialisation Molecular, Cellular and Organismal Biology at Leiden University examines the molecular mechanisms underlying health and disease and how cells and organisms adapt to environmental factors.

This research cluster is a part of the Institute of Political Science’s research programme ‘Institutions, Decisions and Collective Behaviour’. Its members investigate the drivers of political conflict and various types of crises. They study how citizens, political institutions and international organizations…

Are you currently studying medicine and considering the master's Health, Ageing and Society? Read more about what the master's programme can mean for you!

This article discusses the degree of independence that is required for national human rights institutions to function successfully.

Medical technology has become an essential part of healthcare. Innovative treatment methods therefore require a new type of medical professional. Someone with medical and technical knowledge, who builds a bridge between technology and patient.

Restructuring and insolvency laws play a pivotal role in addressing the often conflicting interests of stakeholders of financially distressed companies. Whereas financial distress is an inherent risk of entrepreneurship in market-based economies, legal tools serve an important role to ensure an orderly…

The fifth Owada Chair Symposium included two sessions of student debate together with Professor Owada and the keynote speaker, Dr Fatou Bensouda.

Tonight 20:25, Julia Cramer, expert in quantum information and communication science, is a guest in the television science programma Atlas

The project has been done in the Quantum Matter Optics group under the supervision of Dr. Wolfgang Löffler and Prof.dr. Carlo Beenakker. The title of the presentation is:

The magazine New Scientist selected 25 nominees from candidates proposed by all Dutch and Belgian universities for the New Scientist Science talent 2015 election. One of these nominees is dr. Marieke Liem, who works at the Centre for Terrorism & Counterterrorism.

An overview of awards and prizes granted to our staff and students in 2018, as well as special appointments and royal distinctions.

The Nobel Prize in Physics 2016 goes to David Thouless, Michael Kosterlitz and Duncan Haldane for theoretical discoveries in the field of topological materials. Haldane spent part of 2008 in Leiden; he is the 14th Lorentz Professor to win a Nobel Prize.

From July 22nd to August 1st, the Leiden Institute of Physics organizes its annual summer school, titled ‘Modern Physics at all Scales’.

On the evening of Tuesday January 31st, the physics institute organizes its triannual meeting for over seventy high school teachers. The program consists of lectures on developments in modern physics and the latest initiatives in the world of education.

From 16 to 26 July, the Leiden Institute of Physics organizes its annual summer school, titled ‘Modern Physics at all Scales’.

An overview of awards and prizes granted to our staff and students in 2020, as well as special appointments at Leiden University and other institutions.

The winner of the Paul & Tatiana Ehrenfest physics thesis prize 2020 is Koen Bastiaans. He carried out his PhD research in the group of Milan Allan and defended his thesis in December 2019 cum laude at Leiden University.

The Leiden Institute of Physics has been awarded three out of twelve available grants from the FOM Projectruimte. Principal Investigators Milan Allan, Stefan Semrau and Carlo Beenakker all receive around 400,000 euro for their research.

The 2018 Physics Nobel Prize is awarded to Arthur Ashkin, Donna Strickland and Gérard Mourou for their research on optical tweezers based on lasers. Leiden physicists comment in the following media.

Following in the footsteps of Professor Jan Zaanen, visiting fellow Louk Rademaker is exploring quantum effects in so-called strange materials. His research is paving the way for new materials that could be used in emerging technologies.

A novel in vivo model system for studies on glucocorticoid resistance

When you walk into the Gorlaeus Building, you will notice it immediately; the artwork 'The Cloud' hangs prominently in the hall and cannot be missed. Artist Jos Agasi designed it especially for this location. ‘Intuition, imagination and creativity. Scientists and artists have more in common than they…

The genomic DNA of every organism is organized and compacted in order to fit inside the cell. This is achieved by the joint action of numerous architectural proteins that aid in folding the genome. Genome folding is tightly interconnected with transcription, with genes in certain regions being silenced,…

Researchers from five different discplines work together in this interdisciplinary initiative.

This project aims to identify which aspects of exploring a novel environment produce beneficial effects on memory. The effects of novelty will be investigated across the lifespan, including children, adolescents and older adults.

Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…

Professional learning communities are useful for professionalization but also for the development of induction programmes. In this project, we combine these two worlds into a professional learning communities in which mentors or novice teachers learn about mentoring and at the same time develop an induction…

How did free agents oppose the monopolies held by the VOC and WIC in court?

This project is aimed at 1) elucidating the role of attention in itch and pain, including orientation, and attentional disengagement (i.e., directing attention away) from itch and pain; and 2) modifiability of these attentional processes.

Meet the people of the Resilience Center

LED3 is the combined effort of four excellent institutes of Leiden University. Through joined hands, we are able to give rise to a more effective early drug discovery pipeline. Let us briefly introduce the institutes.

PhD defence

The Dick Stufkens Prize 2020 for the best PhD thesis of the Holland Research School of Molecular Chemistry has been awarded to Dr Mark Koenis. Koenis graduated 21 February with the distinction cum laude on his thesis 'Advanced Spectra Analysis to Determine Complex Structure and Chirality'. He describes…

Electrons in graphene behave like light particles; they have no mass and can penetrate everything: very useful if you dream about nano-electronics. But you do have to channel them. Carlo Beenakker will be researching how. He has been awarded an ERC Advanced Grant of 1.5 million euro to carry out this…

Connecting worlds, enhancing research and teaching, and providing innovative solutions to complex social issues: that is the idea behind interdisciplinary research. In that respect, a huge amount happened at Leiden University in 2023.

Why do we need fundamental science? For a lot of reasons, speakers showed at the Lustrum Symposium ‘Science Matters’. This symposium was held on 18 March 2016 to celebrate the 200th anniversary of the Faculty of Science.

In 2021 many of our students and staff won fantastic prizes and were awarded important research grants. This is our traditional review of these successes as the end of one year marks the beginning of another.

On this page you will find an overview of awards and prizes granted to our staff and students in 2026, as well as special appointments at Leiden University and other institutions.

Can epigenetic changes explain associations between early life stress and health outcomes?