1,778 search results for “molecular biology” in the Public website
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Galaxies and the structures in which they are embedded
Researchers at Leiden Observatory study the fundamental physics that creates structure in the Universe. These processes collect matter into galaxies and gas into stars. With the use of powerful telescopes and advanced calculations and computer simulations, Leiden astronomers seek to understand the origin,…
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Binding kinetics
A tantalizing concept that has emerged in our recent research is binding kinetics. An important parameter is residence time (RT), a direct reflection of how long a drug stays bound to its target. This parameter is of crucial importance, because drug action lasts only as long as the receptor-ligand complex…
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Dame Lab / Chromatin Organization & Dynamics
Throughout all domains of life, from bacteria and archaea to eukaryotes, genomes adopt well-organized three-dimensional structures that can change in space and time to accommodate preferred transcriptional programs for environmental adaptation, the maintenance of cellular identity and differentiation…
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PhD Theses
A full overview of MCBIM PhD theses.
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Vision and Imaging
On the basis of the characteristic aspects of a picture, certain computers can tell us what the picture is showing. They can learn this in the same way that young children are able to learn to recognize images. Further improving these techniques opens the way to a whole range of new applications. Biology…
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Research Projects, Categories and Supervisors
These are the proposed research projects for LEAPS 2019. Please note that not all projects will go ahead and some may still be added in the near future. Final funding decisions lie with the Faculty sponsors. And please make a note that if you are interested in an ESA project, to check if your state…
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Student life
Your time at Leiden is about more than just studying. Some of your best experiences will stem from being a part of our lively and diverse student community, as well as from life in the beautiful city of Leiden.
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Programme structure
Courses cover a broad range of relevant subjects and provide in-depth theoretical knowledge as well as training in practical skills and advanced research tools.
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Friends and foes from the past – fungi in historical Leiden University collections
Which fungi live in Leiden University’s historic buildings and collections, and how can their impact on heritage and human health be understood and managed?
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Plant ageing, rejuvenation and life history strategy
What are key regulators of plant ageing that can reverse ageing in plants (rejuvenation), and how can we use this knowledge to improve crop plants?
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Other nominees
Discover all the Leiden Science teaching talent that was part of this year's lineup.
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Panic disorder and the brain: the largest study ever conducted
Panic disorder is associated with changes in the brain, both in children and adolescents and in adults. This is the main outcome of the largest brain study ever conducted on panic disorder. Lead researcher and coordinator of the study, Moji Aghajani (Institute of Education and Child Studies), explains…
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Science and business working together on affordable alternatives for antibiotics
Almost fifty scientists and twenty companies will be working on developing new antibiotics and alternatives for antibiotics use. NWO and the Ministry of Health, Wellbeing and Sport will together invest close to seven million euros in this research. Scientists from Leiden University and LUMC will be…
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No venom resistance in snake-eating birds: ‘They just don’t need it’
To eat or get eaten. It describes the evolutionary race of snakes versus the mammals and birds that prey on these snakes. Muzaffar Ali Khan devoted his PhD to investigating the molecular mechanisms play of the evolutionary arms race, and has his promotion 16 February. What makes mammals and birds successful…
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A chemical connection that affects your immune system
A group of chemists, that includes Sander van Kasteren and Hermen Overkleeft, has discovered that azides, a certain type of chemical compound, can determine whether or not T cells respond to or ignore a vaccine. Their discovery is set to be published in Angewandte Chemie.
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PhD-vacancy at the IBL on the neurogenomics of vocal learning
This project on the role of FoxPs in vocal perception and production learning is part of nine PhD-positions funded by the NWO Gravitation Programme which was granted to the Dutch Research Consortium 'Language in Interaction'
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Research Grant for tuning into photosynthesis
Biophysicist Anjali Pandit has been awarded a FOM 'Projectruimte' research grant for her proposal ‘Tuning into the photosynthetic membrane with atomistic precision’.
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AI application in pathology reveals novel insights in endometrial cancer diagnostics
Research at the Leiden University Medical Center (LUMC) Department of Pathology shows the power of artificial intelligence (AI) applied to endometrial carcinoma microscopy images. The group of Dr. Tjalling Bosse offers novel insights that could improve diagnosis and treatment of uterine cancer. Their…
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Nienke Beets wins prize for connecting nature and art
Nienke Beets of the Leiden Hortus botanicus has won the brand new Joke 't Hart Prize for connecting nature and art. For the botanical garden in Leiden, she developed a series of colourful plant icons and an educational board game. On 20 May, the Dutch Association of Botanical Gardens (NVBT) unanimously…
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Leiden Professor Cees van den Hondel appointed ‘Officier in de Orde van Oranje-Nassau’
Cees van den Hondel, IBL-professor and 2010 Programme director of the Fungus programme of the Kluyver Centre received the royal distinction
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How public money for science leads to new medicines
Public funding for fundamental research is essential for innovation and the development of new medicines. This is demonstrated by Professor Science Based Business Simcha Jong and his colleague Hsini Huang after studying US federal funding restrictions for stem cell research under President George W.…
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How touchscreens and eye trackers can tell us something about the dating life of orangutans
Aesthetic attraction plays a big role in orangutans’ mate choice, behavioural biologist and PhD candidate Tom Roth has observed. But to discover just how big that role is, more research is needed into the emotions of the great apes.
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This week the National Antibiotic Development Platform, NADP, was officially launched via a meeting in Utrecht.
Antibiotic resistance is one of the major threats to human health. This week the National Antibiotic Development Platform, NADP, was officially launched via a meeting in Utrecht, with many of the stakeholders in the field present.
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Artificial intelligence helps in the search for new antibiotics
With the search for new antibiotics becoming increasingly urgent, artificial intelligence offers valuable help. Smart software developed by Leiden PhD candidate Alexander Kloosterman searched genomes of bacteria and found clusters of DNA that code for proteins that have an antibiotic effect. ‘This new…
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LED3 Lecture: Harnessing plant metabolic diversity for food and health applications
Lecture
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Awards and Grants 2018
An overview of awards and prizes granted to our staff and students in 2018, as well as special appointments and royal distinctions.
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Two NWO ECHO grants for Leiden Chemistry
Two excellent young chemists, Jeroen Codée and Sander van Kasteren, have received an ECHO grant for €260,000 from the Netherlands Organisation for Scientific Research (NWO). This funding will allow them to begin their research projects.
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Ewine van Dishoeck awarded prestigious Schwarzschild Medal
The German Astronomical Society has awarded the 2019 Karl Schwarzschild Medal to professor of Molecular astrophysics Ewine van Dishoeck. She will receive the medal during the annual meeting of the society from 16 to 20 September 2019 in Stuttgart.
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Sensing drug responses of single cells using optical tweezers
Light can be used to apply forces on single cells. Focused lasers have been used by physicists to tweeze particles and to manipulate them. These so called “optical tweezers” can be used as mechanical phenotyping tools for characterising the mechanics of materials and living objects.
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Bert Meijer reappointed to the Board of Governors
Professor Bert Meijer has been reappointed as a member of Leiden University’s Board of Governors by the Minister of Education, Culture and Science, Ingrid van Engelshoven.
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Fred JanssenICLON
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Awaken sleeping antibiotics with ERC Advanced grant
To facilitate the search for new antibiotics. That is the aim of Gilles van Wezel, professor molecular biotechnology at the Institute of Biology Leiden (IBL). He wants to do this by looking at similarities in the DNA of antibiotic-producing bacteria. Van Wezel has been awarded an ERC Advanced grant…
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Amy Montanje receives the 'Kees Bakker Award'
Leiden Biology student Amy Montanje received the annual award for being the best BSc-student in 2018 from the “Stichting Professor Dr. K. Bakker-fonds”.
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Gravitation Grant: more than twenty million for sustainable crops
The project MiCRop receives 20.3 million euros from the Gravitation programme of the Dutch Research Council (NWO). MiCRop will unravel the microbial community around crops. This knowledge will help to develop more sustainable crops that require fewer fertilizers and pesticides. Leiden professors Jos…
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‘Like Don Quichot, you have to keep dreaming’
Having a bachelor, master and Ph.D in chemistry, Elena Sánchez López shifted to a more biological research for her postdoc. All of her studies she did at the University of Alcala, in Spain. Way back in medieval times, this city was the place of birth of Miguel de Cervantes, author of the world famous…
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Screening enormous databases to find a cure for cancer
Pharmaceutical research should make more use of data science, says Gerard van Westen, postdoctoral fellow at the Leiden Academic Centre for Drug Research (LACDR). ‘If we want to have better drugs, we should start with data.’
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Leiden expands collaboration with Mexico
A delegation from Leiden University is currently visiting Mexico to initiate collaboration with universities and science funding bodies in the country and to extend and expand existing partnerships. Rector Magnificus Carel Stolker is confident enough already to call it a success.
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The bite that heals: New antibiotics with help from venomous animals
Prof. Gilles van Wezel and Prof. Mike Richardson of the Institute of Biology Leiden received €1.4 million to find new antibiotics.
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Ewine van Dishoeck in Board of Trustees Institute for Advanced Study
The Institute for Advanced Study has appointed astronomer and chemist Ewine Fleur van Dishoeck to its Board of Trustees, effective 5 May, 2018.
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The Erasmus+ grant opens doors
What is it like to participate in the Erasmus+ grant programme as a Master's student from Ukraine? Yevhenii Radchenko did an eight-month internship at Leiden University in 2018. Soon after, he returned as a PhD candidate. 'You have little to lose, but a lot to gain.'
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Brand-new professor Gerard van Westen wants to cross boundaries
Brand-new professor Gerard van Westen works at the intersection of artificial intelligence and drug development. For the new chair in Artificial Intelligence and Medicinal Chemistry, he uses computer models to make drug development more efficient. Our ultimate goal is a virtual human which allows you…
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Finally solved: how the body's own marijuana spreads through the brain
Since its discovery thirty years ago, it remained a mystery: how does the body’s own marijuana move between nerve cells in the brain? Mario van der Stelt and his research group have now uncovered the answer. This insight could aid the development of new treatments for pain and neurological disorders…
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Ewine van Dishoeck receives the Niels Bohr medal
Leiden professor of molecular astrophysics and astrochemistry Ewine van Dishoeck was presented with the Niels Bohr International Gold Medal on Friday 7 October. The medal, instigated by the Danish Society of Engineers IDA, was awarded by Queen Margrethe of Denmark at a ceremony at the Carlsberg Academy…
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Dick Stufkens Prize 2020 awarded to physical chemist Mark Koenis
The Dick Stufkens Prize 2020 for the best PhD thesis of the Holland Research School of Molecular Chemistry has been awarded to Dr Mark Koenis. Koenis graduated 21 February with the distinction cum laude on his thesis 'Advanced Spectra Analysis to Determine Complex Structure and Chirality'. He describes…
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Dick Stufkens Prize 2025 awarded to physical chemist Begüm Demirkurt
The Dick Stufkens Prize 2025 for best PhD thesis of the Holland Research School of Molecular Chemistry (HRSMC) has been awarded to Begüm Demirkurt for her thesis “Mechanical Contact Imaging using Fluorescence Techniques”. Demirkurt, who obtained her doctorate from the University of Amsterdam last March,…
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Protecting the tiniest lives: how biological signals can improve care for premature babies
When a baby is born too soon, every minute counts – and so does every decision. To reduce uncertainty in those critical moments, biopharmaceutical scientist Manchu Umarani Thangavelu dedicated her PhD to identifying molecular markers of preterm birth and neonatal infection.
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Scouring the brain for causes of psychiatric illnesses
What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’
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Singing parrots wanted: is our musicality unique?
Is our musicality unique? That’s what the Bird Singalong project aims to find out. And for that, they need the help of feathered friends from all around the world. ‘By researching how parrots learn songs, we also learn more about the origin of our own musicality.’ Do you have a parrot that can sing…
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Oncode Accelerator launched: patients at the centre of innovative cancer drug development
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process.
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Hermen Overkleeft wins the 2015 Jeremy Knowles Award
Prof. Hermen Overkleeft has been awarded the 2015 Jeremy Knowles Award of the Royal Society of Chemistry for his innovative and insightful development of activity-based protein probes for the imaging and identification of enzymes in health and disease.
