Mental health issues in the Dutch court: The criminal court as a border guard between the regular Mental Health System and the Criminal Justice system?

People who have taken antibiotics in the past three months pay more attention to negative facial expressions, according to research by postdoc Katerina Johnson and assistant professor Laura Steenbergen. This may explain how antibiotics increase the risk of developing depression.

Pseudomonas Aeruginosa is a Gram-negative bacterium which can form biofilms, increasing its resistance against antibiotics and the host immune system. Polysaccharides are an integral part of this biofilm, one of these polysaccharides is called Psl. PslG is a glycosidase, able to cleave this polysaccharide,…

El Chorro de Maita, Cuba

Animal models suggest that the chemokine ligand 2/CC-chemokine receptor 2 (CCL2/CCR2) axis plays an important role in the development of inflammatory diseases. However, CCR2 antagonists have failed in clinical trials because of a lack of efficacy.

Promotor: J. A. Bouwstra

Caribbean archaeological heritage is threatened by natural impacts but also increasingly by economic developments, often resulting from the tourist industry. The continuous construction of specific projects for tourists, accompanied by illegal practices such as looting and sand mining, have major impacts…

The zebrafish is a promising vertebrate model organism in early drug discovery and development.

This thesis is concerned with the constitution of chiral responsive matrix assemblies that may undergo light-driven conformational changes and self-select vibrations to develop vibronic states for driving semi-classical coherent transfer with nearly 100% yield in a lossless NCAP process.

This reflection for Critical Studies on Terrorism, explores two decades of the 'War of Terror' and what it means today.

The League Against Imperialism: Lives and Afterlives explores the dramatic and engaging story of a global institution that brought together activists across geographical and political borders for the goal of eradicating colonial rule worldwide.

Research on lethal violence related to criminal activities.

Recent studies of Neandertal body mass and skin surface indicate raised energetic requirements in this lineage compared to anatomically modern humans.

The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.

The heritage of Indigenous Peoples has long been researched and commented upon from the outside. This book adopts an innovative approach by engaging with the heritage of Indigenous Peoples from the ‘inside’.

Sustainable energy from wind and solar is most readily available near the sea.

On April 26th, Kate Bellamy succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Kate on this great result.

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).

How can mentors and social workers foster the vocational identity of at-risk youth and improve their prospects?

Sorghum (Sorghum bicolor) is a major cereal crop that millions of subsistence farmers in Sub-Saharan Africa (SSA) rely on. However, the scourging impact of the root parasitic weed Striga (Striga hermonthica, a.k.a. “witch-weed”) has remained a major constraint hampering the productivity of sorghum in…

Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…

To goal of this project is to get a deeper, more comprehensive and up to date understanding of the state of University-Business Cooperations (UBC) in Europe, from the perspective of both the Higher Education Institutions and the business sector.

In this on-line dissertation, jazz saxophonist Dick de Graaf investigates a variety of compositional and improvisational models and techniques in contemporary jazz and Western art music, and discusses possible applications of these materials in current jazz practices.

Promotor: Prof.dr. J. Kuiper

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

In my research, we developed a method to distinguish knots. A knot is a mathematical depiction of the everyday knot that occurs in ropes and cords.

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

The Children’s Rights Monitor provides a thematic overview of the implementation of the UN Convention on the Rights of the Child in the Netherlands.

On 2 May, Sophie Starrenburg defended the thesis 'Striking a balance between local and global interests: communities and cultural heritage protection in public international law'. The doctoral research was supervised by Nico Schrijver and Yvonne Donders.

On November 1st, Min Liu succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Min on this great result.

After 20 years of police reform, Jasper De Paepe and Marleen Easton look back and discover what we can learn about partnerships between police and science in Belgium.

In our current system, many tasks and roles are undervalued.

Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…

With increasing carbon dioxide levels in the atmosphere and their detrimental effect on the global climate, modern society needs to push for more renewable energy sources. Storing widely accessible and abundant solar energy in chemical bonds in the form of molecular fuel via artificial photosynthesis…

The level of congruence between parties and their voters can vary greatly from one policy issue to another, which raises questions regarding the effectiveness of political representation. We seek to explain variation in party–voter congruence across issues and parties.

This handbook provides a resource for those already familiar with some kinds of micro-particles who wish to learn more about others, or for those just starting out in the study of microremains who wish to have a broad understanding about microscopic archaeology.

The LOFAR radio telescope produces petabytes of data every year. Radio Astronomers use complex multi-step pipelines to process this data and produce scientific images.

Dendritic cells (DC) play a prominent role in the priming of CD8(+) T cells. Vaccination is a promising treatment to boost tumor-specific CD8(+) T cells which is crucially dependent on adequate delivery of the vaccine to DC.

Alongside Leiden, Leiden University has a second hometown: The Hague.

Promotor: A.P. IJzerman

In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.

-

The first index to measure product safety, sustainability, and circularity, operationalising the EU’s (SSbD) framework.

In light of climate change, it is crucial to determine whether plant species can adapt to future climates to avoid extinction. Plants adapt to various conditions by altering their functional traits, such as leaf size or photosynthetic rate. Some traits appear linked and vary together between species,…

For optimization problems, it is often unclear how to choose the most appropriate optimization algorithm. As such, rigorous benchmarking practices are critical to ensure we can gain as much insight into the strengths and weaknesses of these types of algorithms.

In Indigenous Ancestors and Healing Landscapes Jana Pešoutová presents new interpretations of current healing practices in Cuba and the Dominican Republic juxtaposed against the European colonization of the Caribbean after 1492.

In this dissertation, electrophysiological (EEG) and behavioural measures are used to investigate how allophonic tonal variants and sub-phonemic features are processed during Mandarin and Dutch speech production, visual processing of written words and reading aloud.

Aspergillus niger is an important industrial producer of organic acids and enzymes producing large amounts of spent fungal biomass.