191 search results for “vries” in the Public website
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About the Department
Our staff has a strong international reputation and a broad research network, facilitating international student exchange. They lead projects world-wide, from France to the Caribbean, and from Ethiopia to Russia.
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Research Support Team
The Research Support Team (RST) at the Institute of Security and Global Affairs provides comprehensive support and timely advice to researchers in identifying relevant grant schemes or funding systems.
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Voices of experience in periviable decision-making and artificial placenta technology
PhD defence
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Organisation
The Executive Committee consists of the following members:
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De aanpak van ondermijning en financieel-economische criminaliteit
Deze onderzoeksgroep richt zich op het thema ondermijning en financieel-economische criminaliteit, in het bijzonder de aanpak ervan op een aantal deelterreinen.
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Key publications
Key publications of the Cardiovascular Pharmacology group
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The Nature of the Workmen's Marks and Their Interaction with Writing
The project concerns the nature, the usages and functions of pictographic systems in relation to writing in societies with (restricted) literacy.
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The Sand Motor - Building with Nature to optimise coastal protection and other ecosystem services
How can mega sand nourishments, such as the Sand Motor, be designed and managed for optimal ecosystem services provision ?
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Selectivity
Target selectivity is an important aspect of any drug molecule, and certainly a parameter to be optimized. That is not trivial for a number of reasons. First of all hundreds of drug targets (receptors, enzymes, ion channels) exist, and no single lab in the world has assays for all of them.
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Public leadership as a balancing act? How leaders’ context influences leadership
Public leadership received increasing attention, but we still do not understand how the context of public leaders affects leadership. This research project delves into public leaders’ perceptions of the leadership situations they find themselves in, which are characterised by multiplicity – one could…
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Agonists for the Adenosine A1 Receptor with Tunable Residence Time. A Case for Nonribose 4-Amino-6-aryl-5-cyano-2-thiopyrimidines
Source: J Med Chem, Volume 57, Issue 8, pp. 3213-22 (2014)
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Non-take-up of social support and the implications for social policies
This dissertation takes an important step in understanding the phenomenon of non-take-up of social support and what it means for contemporary social policies.
- NWIB
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Governance of Innovation Project Management: Necessary and Neglected
Promotores: B.R. Katzy, J. de Vries, Co-Promotor: L.P. Groenewegen
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Evaluation of (4-Arylpiperidin-1-yl)cyclopentanecarboxamides As High-Affinity and Long-Residence-Time Antagonists for the CCR2 Receptor
Animal models suggest that the chemokine ligand 2/CC-chemokine receptor 2 (CCL2/CCR2) axis plays an important role in the development of inflammatory diseases. However, CCR2 antagonists have failed in clinical trials because of a lack of efficacy.
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Affinity
Designing and synthesizing high-affinity ligands for a given drug target have always been among the more important challenges in the drug discovery process.
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Targeted Informed consent: empowering young participants in medical-scientific research
Promotor: J.M. van den Broek Co-promotor: M.C. de Vries
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When structure-affinity relationships meet structure-kinetics relationships: 3-((Inden-1-yl)amino)-1-isopropyl-cyclopentane-1-carboxamides as
Source: Eur J Med Chem (2015)
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Allosteric Modulation
Allosteric modulation has long been recognized as a general and widespread mechanism for the control of protein function. Modulators bind to regulatory sites distinct from the active site on the protein, resulting in conformational changes that may profoundly influence protein function. This concept…
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Prof. dr. J.D. Speckmann prize
Annually the Institute of Cultural Anthropology and Development Sociology awards the Speckmann prize for the best Fieldwork NL report, as well as the most accomplished master’s thesis.
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About us
The Faculty of Archaeology at Leiden is the leading academic institute for Archaeology in the Netherlands, and one of the largest in the world. The Faculty is an international front-runner, in the top ten of the QS World University Ranking, at subject level.
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Towards a comprehensive understanding of (facilitating) teacher professional development
What are ‘missing links’ in research on teacher professional development trajectories? We focus on the role and development of teacher facilitators in designing and implementing (collaborative) professional development trajectories.
- Neerlandistiek Master Universiteit Leiden
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Receptor Residence Time
Research question
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The Postal Imagination: Returning Mail in Contemporary Culture
How to understand the simultaneously dis- and reappearance of letters in contemporary culture, and how does this Neo-Epistolarity relate to media-technological change?
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Organisation
Institute of Political Science
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Book presentations
Now and then we organise book launches to present the latest publications, both academic and popular, in our broad field.
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Hall of Fame 2023
In 2023, many of our students and staff won great prizes and secured important research grants.
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Our people
Some examples of AI-research done at Leiden.
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Research and design in secondary science education
Research and design are becoming more and more important in international science education. In The Netherlands, two recently introduced subjects focus on research and design activities in the classroom: O&O (research and design) and NLT (nature, life and technology). This research aims to look at what…
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Functions of autophagy in the filamentous fungus Aspergillus niger
What are the functions of autophagy in the filamentous fungus Aspergillus niger?
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Allosterism
The recognition that there may be more, so-called allosteric binding sites on a given receptor has also fueled our synthetic efforts. Over the last few years we have focused on many drug targets (adenosine A1, A2A and A3 receptors, the mGlu2 receptor and a classic ‘anti-target’, the hERG channel) to…
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Key publications
Key publications of the Predictive Pharmacology group.
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Kraft Lab - Self-assembly in Biological and Soft Matter
Research in the Daniela Kraft Lab focuses on self-assembly in biological and soft matter systems, ranging from anisotropic colloidal particles to lipid membranes, emulsions, and viruses.
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Cell Wall Dynamics in Aspergillus niger
This functional genomics project aims at understanding the biology of the underlying mycelium differentiation and autolysis processes in much more detail.
- Career prospects
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‘First determine goals, then make healthcare choices’
What are the goals of healthcare? That very question must be asked more frequently before healthcare-related choices are made. This is what Martine de Vries, Professor of Normative Aspects of Medicine, advocated during her inaugural lecture on Friday, 2 November 2018.
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Rapport: Opsporing seksueel uitbuiten van jongeren kan effectiever via directe omgeving
Preventie, signalering en opsporing van seksuele uitbuiting van jongeren kan effectiever via buren, klasgenoten en andere mensen uit hun sociale leefomgeving. Dit volgt na onderzoek van universitair docent Ieke de Vries in samenwerking met het Centrum Kinderhandel en Mensenhandel (CKM).
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Exhibition sculpture ‘Zie Justitia’ at Leiden Law School extended until January 2023
The art committee of Leiden Law School has extended the exhibition of the sculptures by the Leiden artist Koen de Vries in the C-wing of the KOG building until January 2023. On Thursday 8 December, the finissage of the exhibition will take place in the C-wing at 16.45 hours with drinks and light sna…
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Inexhaustible source of human heart muscle cells allows strong reduction of animal testing
Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells outside the body. Using a special technique, the researchers have now created…
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What rights do donors have?
Collaboration is worthwhile. A joint LUMC and Leiden Law School project has received €142,500 from the Dutch Research Council (NWO). This grant will advance research into the law and ethics of regenerative medicine.
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NWA grant for health law as part of NWA Cure4life
Mirjam Sombroek, Aart Hendriks and Martine de Vries (LUMC) will work on mapping the ethical and legal aspects of gene therapy. The aim is to establish a best practice of how society can best deal with these therapies. For example with guidelines on how to regulate, reimburse and make these therapies…
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Young transgender people are able to decide about puberty blockers
Young transgender people are able to decide together with their parents on a reversible intervention with puberty blockers. These are the results of a study by LUMC Curium and Amsterdam UMC of 74 young people undergoing treatment. Ninety percent of the young people studied proved able to make an informed…
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Heiko Lohuis
Faculty of Law
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‘It’s a real balancing act for doctors at gender clinics’
Do young people who want to change gender have the unconditional right to medical treatment? Pediatric Endocrinologist Martine de Vries, who is also Professor of Medical Ethics, treats transgender children and adolescents. She will discuss this in her ‘Pride Talk’ on 18 September.
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Previous SAILS Workshops
SAILS likes to occasionally organise workshops about topics that relate to our programme. On this page you can find more information about previous workshops.
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Lipid signaling in brain diseases
Multiple Sclerosis, Parkinson’s and Alzheimer’s disease are the most common neurodegenerative disorders. Unfortunately, no effective treatments are currently available to halt the progression of these neuroinflammatory diseases [1].
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Alumni
Former PhD, Bachelor and Master students of the Van Exter Lab
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Academic freedom is at risk – what steps can we take to defend it?
At the annual research day (‘toogdag’) of the research programme Effective Protection of Fundamental Rights in a Pluralist World (EPFR), researchers reflected on the growing threats scholars face due to political repression, conflict or displacement, and how to protect them.
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Radboud University and Leiden University research ethnic profiling
A research team from Radboud University and Leiden University, led by senior researchers Prof. Masja van Meeteren (RU/UL), Dr Paul Mutsaers (RU) and Prof. Maartje van der Woude (UL), will examine what national and international research has really found about ethnic profiling by the police.