In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.

Physicist Sense Jan van der Molen researches materials that do not exist in nature. ‘It’s fascinating to see how the properties of a material change if we manage to make it super thin.’ He will give his inaugural lecture on 21 October.

Fewer CO2 emissions, less airborne viral transmission, and a more sustainable form of food production: seven consortia of researchers and societal partners will put a budget of 32 million euros towards developing technological innovations. Important Leiden research on circular electronics by Prof. Dr.…

Aleydis Nissen published a feature article on the South Korean electronics industry in Eos magazine. The Pascal Decroos Fund sponsored this article.

Composer, bass player and ACPA alumnus Ilya Ziblat Shay presented a paper at the Music Weekend and Midlands New Music Symposium, organised by Nottingham Forum for Artistic Research.

The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.

This thesis investigated how microphones and loudspeakers could become musical instruments.

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

In order to gain insight into the structure and function of the molecular complexes involved in chemotaxis, we use electron cryotomography (ECT). This technique allows us to directly study microbes in their native state at resolutions capable of visualizing individual proteins.

This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.

This thesis proposes multiple paths towards the development of a performance practice in Computer Music.

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

Artificial photosynthesis has recognised potential to produce green and sustainable fuels from earth-abundant resources such as water, carbon dioxide (CO2), and sunlight.

With the powerful electron microscopes at NeCEN we study abnormalities in cells of blood vessels in cardiovascular disease, the interaction between pathogens and hosts in infectious diseases, molecular processes that cause cancer and the interaction between drugs and target proteins. Drug development…

Bacteria have the ability to alter their morphology in order to adapt to changing environments.

Promotor: Prof.dr. E.J.J. Groenen

Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp

Graphene and other layered materials combine into completely new substances. Leiden physicists establish the ground rules for designing such materials by measuring how the layers in the stack interact. Publication on November 29 in Nature Communications.

Promotor: H.J.M. de Groot, Co-Promotor: A. Alia

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

This thesis described the development of novel scanning tunneling microscopy techniques to investigate strongly correlated electronic states in quantum matter.

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

I will give a general introduction to the field of molecular electronics, its history, methods and challenges. I will also introduce the subject of my investigation and provide a brief outlook to the remainder of our thesis.

Nature publishes an article on a paradoxical discovery in superconductivity. Physicists are searching for superconductivity at high temperatures so that less cooling is needed in for example MRI machines. News & Views article by Prof. Jan Zaanen in the same issue of August 19th.

The majority (80%) of e-waste generated globally are recycled informally in developing countries.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

The Microscopy Unit houses, maintains and coordinates most of the microscopy equipment of the IBL. The available equipment ranges from conventional light and fluorescence microscopes, to confocal laser scanning and electron microscopes. In addition, infrastructure is available for histology, including…

Meindert H. Lamers is co-director of the Netherlands Center for Electron Nanoscopy (NeCEN) at the Faculty of Science and head of the section Light and Electron Microscopy at the Leiden University Medical Center (LUMC). His research group at the LUMC studies molecular mechanisms of DNA replication and…

The endophytic microbiota is a community of various microorganisms that reside in plant tissue. These microbes are known to promote plant health and resilience, and their members do not simply exist side by side.

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

How can challenge-based learning in higher education contribute to sustainable urban waste management and support The Hague’s transition to a zero-waste city by 2050?

Jörg Meyer investigates energy conversion at interfaces at the atomic scale. Starting from the Schrödinger equation, he develops and employs computer simulation techniques.

This thesis comprises the development of reproducible synthesis procedures for two-dimensional materials (composed of boron, nitrogen and carbon) on different metallic surfaces.

Electrons in a crystal lattice have properties that may differ from those of a free electron in vacuum.

In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.

Promotor: Prof.dr.ir. T.H. Oosterkamp, N. de Jonge

The goal of Geert-Jan Kroes is to achieve the ability to predict the outcome of dissociative chemisorption reactions of small molecules on transition metal surfaces. This requires an accurate modeling of the molecule-metal surface interaction and of the reaction dynamics, including energy dissipatio…

Research groups in the Quantum Matter & Optics programme investigate electronic properties of matter and light-matter interactions with emphasis on quantum information.

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

The Leiden Institute of Chemistry (LIC) is to be joined by a further two talented young chemists. Bela Bode and Michele Pavanello have each won a Marie Curie subsidy. Bode will be studying electron transport in photosynthesis and Pavanello will be using computer models to study charge transport in large…

During the Leiden Science Family Day, you will visit places that are normally closed to the public: go backstage at the Faculty of Science!

In our lab, we investigate the physics and material properties of low-dimensional systems.

Artificial photosynthesis aims to produce fuels from solar energy using chemical processes. In semi-artificial photosynthesis, a hybrid approach is taken using both chemical and biotechnology approaches. We aim to develop hybrid systems between light-harvesting nanoparticles and redox-enzymes (oxidoreductases)…

The dissociative chemisorption of a molecule on a transition metal surface represents a rate-limiting step in many heterogeneously catalyzed processes, whereby most chemicals are made. In spite of the importance of this reaction, an accurate first principles approach to modeling it does not yet exist.…