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The CC chemokine receptor 2 (CCR2), a member of the G protein-coupled receptor (GPCR) superfamily, is widely involved in autoimmune and inflammatory diseases. However, no drugs for this receptor have made it to the pharmaceutical market yet.

Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.

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On the 28th of June, Laura Smorenburg successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Laura on this achievement!

Surface acoustic waves (SAWs) are mechanical waves that travel along the surface of a material and find many applications in modern technologies due to the ease of excitation on piezoelectric substrates via interdigital transducers (IDTs).

This book investigates how gay-identified immigrants and refugees experience feelings of inclusion or exclusion within a sexually-charged online subculture. Explores the response of ethnic minorities to demonstrations of racism and xenophobia within an intolerant European climate. Challenges political…

Globally and regionally, biodiversity is declining and there are shifts in species’ occurrences and functional traits.

On May 31st, Bobby Ruijgrok succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Bobby on this great result.

Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.

Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…

A stimulating, international and inclusive learning community is a place where everyone is welcome and where we get the best out of our students. We focus on problems that transcend borders and have a global impact; we welcome a range of perspectives; and we conduct internationally comparative resea…

Agriculture is among the most vulnerable sectors to climate change and poorer countries face the most severe difficulties. Coffee farmers in Central America, for instance, are facing multiple and mutually reinforcing crises, including price shocks, outbreaks of pests and diseases, migration, and farm…

How is the effect of kleptocracy on foreign policy change mediated by the political-administrative relationship?

The debate in Europe about digital sovereignty, technological sovereignty, data sovereignty and strategic autonomy has been building over recent years at both the EU level and the level of individual Member States. The different concepts – and their diverse interpretations – cover the sovereignty concerns…

Promotor: Prof.dr. M. Ubbink

Ömer Gürlesin defended his thesis on 28 November 2018

Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.

Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel

Supervisor: Gerard van Westen

In this article, Tokdemir & Klein examine the strategic actions of governments against domestic terrorist groups and domestic terrorist groups’ reactions to such actions.

This book brings together new research on the practices of newsmaking.

Can subgroups of people be differentiated whose attitudes on the Sinterklaas festivities and Black Pete cluster with either a) high Dutch national identification or b) a strong preference for social hierarchy, also known as social dominance orientation (SDO; Pratto et al., 1994)?

At LUCL, researchers aim to understand, describe, and preserve the linguistic diversity of the indigenous Americas.

Can behaviour in an online economic game be understood as a representation of radicalisation propensity?

Nowadays, it is well known that hydrogen and helium (and small traces of lithium and beryllium) were created shortly after the Big Bang, while the heavier elements are created in the cores of stars at different evolutionary stages. When these stars explode as supernovae, they expel metals synthesised…

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

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Understanding individual differences in self-regulation in boys with ODD/CD on the level of brain, cognition and behavior

Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.

Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.

A study of the technology, form, function, and use of pottery from the settlements Uitgeest-Groot Dorregeest and Schagen-Muggenburg 1, Roman Period, North-Holland, the Netherlands

In the Netherlands, levying tax on inheritances at death has been a fact of life for centuries. The presumed double taxation and its sad precursor are elements of the discussion about the levy of this inheritance tax, but so too are the possibilities to reduce the tax through ingenious legal constru…

In this article, Gerrit Dijkstra and Jos Raadschelders from the Institute of Public Administration, focus on Russia’s role in Bosnia and raise some important questions.

Promotor: Prof.dr. J. Kuiper, Co-Promotor: S.C.A. de Jager

The group is involved in training in areas of diagnostic skills, treatment/prevention/intervention, neuropsychological assessment, behavioral observations, clinical interviewing, knowledge of intellectual disability, autism, ADHD, psychosis and aggression.

This book focuses on policing in city-regions in Europe bringing together experts from across the continent to develop a sociology of urban policing and a unique methodology for comparing different metropolises in the same country.

A study into the investment and impact of construction projects on Mycenaean communities in Late Bronze Age Greece

In this opinion article published in World Development, the authors present five research and policy priorities. While it is clear that ‘pluriversal’ designs need to guide the way forward (Kothari et al 2019), defining a set of key pillars can provide direction and purpose across this pluriversality.…

This dissertation focuses on questions about the purposes of education and what it means to be educated. These questions are relevant across time, as the answers to these questions are always to some extent related to contemporary society.

Curved single crystals provide variable, but well-defined surface structures.

Our current research focusses on the exploration of the Universe using the neutrino. This neutral, almost massless and only weakly interacting particle can open a window to the distant Universe and also dense regions from which photons cannot escape.

This thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular…

Aviation safety is of global concern. Yet 43% of countries worldwide lack the expertise and administrative capacity to ensure effective safety oversight of the aviation activities for which they are responsible under international law.

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.

To what extent have the Dutch and British militaries learned from their counterinsurgency operations in southern Afghanistan between 2006 and 2020?

Promotors: C.A.J. Knibbe, Anthonius de Boer, Co-promotor: M.M.J. van der Vorst

Pre-University Classes are intended for high school students who want to do more than is offered in the regular school curriculum. In the classes, students follow special lecture series and through that are introduced to the world of science.

The aim of this research project was to increase understanding of which collaborative learning approaches already exist in conservatoire education, and how implementation of collaborative learning could be supported.