Alongside Leiden, Leiden University has a second hometown: The Hague.

The LOFAR radio telescope produces petabytes of data every year. Radio Astronomers use complex multi-step pipelines to process this data and produce scientific images.

Dendritic cells (DC) play a prominent role in the priming of CD8(+) T cells. Vaccination is a promising treatment to boost tumor-specific CD8(+) T cells which is crucially dependent on adequate delivery of the vaccine to DC.

How can mentors and social workers foster the vocational identity of at-risk youth and improve their prospects?

In my research, we developed a method to distinguish knots. A knot is a mathematical depiction of the everyday knot that occurs in ropes and cords.

This handbook provides a resource for those already familiar with some kinds of micro-particles who wish to learn more about others, or for those just starting out in the study of microremains who wish to have a broad understanding about microscopic archaeology.

In our current system, many tasks and roles are undervalued.

The level of congruence between parties and their voters can vary greatly from one policy issue to another, which raises questions regarding the effectiveness of political representation. We seek to explain variation in party–voter congruence across issues and parties.

Sustainable energy from wind and solar is most readily available near the sea.

To goal of this project is to get a deeper, more comprehensive and up to date understanding of the state of University-Business Cooperations (UBC) in Europe, from the perspective of both the Higher Education Institutions and the business sector.

In this on-line dissertation, jazz saxophonist Dick de Graaf investigates a variety of compositional and improvisational models and techniques in contemporary jazz and Western art music, and discusses possible applications of these materials in current jazz practices.

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).

On 2 May, Sophie Starrenburg defended the thesis 'Striking a balance between local and global interests: communities and cultural heritage protection in public international law'. The doctoral research was supervised by Nico Schrijver and Yvonne Donders.

The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.

The heritage of Indigenous Peoples has long been researched and commented upon from the outside. This book adopts an innovative approach by engaging with the heritage of Indigenous Peoples from the ‘inside’.

With increasing carbon dioxide levels in the atmosphere and their detrimental effect on the global climate, modern society needs to push for more renewable energy sources. Storing widely accessible and abundant solar energy in chemical bonds in the form of molecular fuel via artificial photosynthesis…

The ambition of the Medical Systems Biophysics and Bioengineering group led by Alireza Mashaghi is to develop and use physics and engineering concepts and tools for pathophysiology, diagnostics and therapy.

Aspergillus niger is an important industrial producer of organic acids and enzymes producing large amounts of spent fungal biomass.

Promotor: A.P. IJzerman

In Indigenous Ancestors and Healing Landscapes Jana Pešoutová presents new interpretations of current healing practices in Cuba and the Dominican Republic juxtaposed against the European colonization of the Caribbean after 1492.

Self-assembly is an abundant process in nature and is vital to many processes in living organisms.

The last decades it is increasingly recognized that acute as well as chronic postoperative pain is an important problem. Treatment and prevention of postoperative pain is a challenge, especially in special patient populations where there is only limited guidance on how to optimally use opioids.

Promotores: J. Jonkers, K.E. de Visser

In light of climate change, it is crucial to determine whether plant species can adapt to future climates to avoid extinction. Plants adapt to various conditions by altering their functional traits, such as leaf size or photosynthetic rate. Some traits appear linked and vary together between species,…

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

The Children’s Rights Monitor provides a thematic overview of the implementation of the UN Convention on the Rights of the Child in the Netherlands.

On November 1st, Min Liu succesfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Min on this great result.

Effects of maternal smoking, premature birth, intra-uterine growth retardation and asphyxia on child development.

Sarah Giest, Assistant Professor at Leiden Univeristy, researched the topic of regulatory and market structures that affect nudge implementation by private actors, captured by the ‘budge’ idea.

In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.

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The first index to measure product safety, sustainability, and circularity, operationalising the EU’s (SSbD) framework.

In this dissertation, electrophysiological (EEG) and behavioural measures are used to investigate how allophonic tonal variants and sub-phonemic features are processed during Mandarin and Dutch speech production, visual processing of written words and reading aloud.

This dissertation investigates the fabric and the infrastructure of contemporary artistic production.

On July 5th, Mulugeta Tarekegne Tsegaye succesfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Mulugeta on this great result.

Unmanned aerial vehicles (UAVs), often referred to as drones, have become easy and inexpensive to buy, and it is generally expected that the use of drones by private individuals, businesses and public authorities will increase tremendously in the coming years. This raises questions as to what is technologically…

Heterogeneous catalysis is essential to many industrial applications. These catalysts are often comprised of supported nanoparticles, which contain various different surface sites.

On Thursday 16 November 2017 Thomas Leclerc defended his PhD Dissertation ‘A Corrective Approach to Reduce Aircraft Greenhouse Gas Emissions. Contribution to the Study of Interactions between Legal Orders of International Law’. The Supervisors are Professor P. Mendes de Leon and Professor L. Grard.

Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…

What kinds of vocal music were not typically transmitted in written musical notation? Can specific ‘lost’ song forms - siciliane, giustiniane, le Grechesche, gli stili “regionali“ nel canto del quattrocento - be more precisely identified than they have been until now, both in musicological research…

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On 22 February, Elody Hutten defended the thesis 'Tax Professionals Under Societal Pressure: A Dutch Case Study on Responses to BEPS'. The doctoral research was supervised by Henk Vording en Jan Vleggeert.

Announcement of the publication of Vamping the Stage: Female Voices of Asian Modernities, the first book-length study of women, modernity, and popular music in Asia (University of Hawai'i Press, 2017).

On the 6th of November, Virginia Beavon Ham successfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Virginia on this achievement.

The subject of this thesis, ‘Approach to Markov Operators on Spaces of Measures by Means of Equicontinuity’, combines an analytical and probabilistic approach to Markov operators.

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

The ethics of ghosts, spectres, and mediums in postcolonial literature

This book looks to existential thinkers for reasons to hope immortal life could be worth living. It injects new arguments and insights into the debate about the desirability of immortality, and tackles related issues such as boredom, personal identity, technological progress, and the meaning of life…