New article on popular culture influences on cybersecurity experts, available Open Access at Contemporary Security Policy, part of a special issue edited by dr. Myriam Dunn Cavelty.

Kamerlingh Onnes Building, Steenschuur 25, 2311 ES, Leiden

The indane (2,3-dihydro-1H-indene) ring system is an attractive scaffold for biologically active compounds due to the combination of aromatic and aliphatic properties fused together in one rigid system.

After graduation you have a lot of opportunities: academics are highly sought after in Dutch secondary education or mbo teaching. You can also aim for a management position or work as a researcher within the field of Life Sciences.

In the Master’s programme Research in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.

Breast cancer is the most common cancer in women worldwide. Metastasis, the process by which cancer cells spread to other parts of the body, makes treatments less effective. It is important to unravel the mechanism of metastasis.

Source: Org Biomol Chem, Volume 13, Issue 8, pp. 2407-22 (2015)

Promotor: Prof.dr. M. Danhof, Co-Promotor: J. de Jongh

Currently, several successful vaccines are available. However, for pathogens with a highly variable genetic composition, and for which serum IgG antibodies are not a useful correlate of protection, effective vaccines are yet to be developed.

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

Source: Structure , Volume 22, Issue 8, pp. 1120-1139 (2014)

The PML specialisation prepares you with knowledge and understanding of the key concepts and theories of management, leadership, decision-making and policy implementation in national and international government organizations.

Source: Nat Biotechnol, Volume 32, Issue 12, pp. 1213-22 (2014)

This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.

Cell-based medicinal products (CBMPs), such as CAR T cells, are highly complex biopharmaceutical products offering various treatment options for serious illnesses such as cancer or autoimmune diseases.

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

Source: Mediators Inflamm (2014)

Rutger Leukfeldt, special chair of Governing Cybercrime, and colleagues investigate the link between Protection Motivation Theory (PMT) factors and self-protective online behavior.

Leiden University is an international, broad-based university. We distinguish five core domains for our research and teaching activities.

Supervisor: Gerard van Westen

In this article, Tokdemir & Klein examine the strategic actions of governments against domestic terrorist groups and domestic terrorist groups’ reactions to such actions.

Which challenges exist for girls to effectuate their right to education and specifically getting access to education?

Source: Eur J Med Chem, Volume 101, pp. 681-91 (2015)

The researchers explore how instructional risk communication can support public safety during nuclear emergencies.

Oude UB, Rapenburg 70, 2311 EZ, Leiden

The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Immunotherapies for cancer are an emerging class of therapeutic strategies which aim to treat cancer via augmentation of the immune system.

PURPOSE: The aim of the study was to develop a cheap and fast method to produce hollow microneedles and an applicator for injecting vaccines into the skin at a pre-defined depth and test the applicability of the system for dermal polio vaccination.

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

FSW building, Wassenaarseweg 52, 2333 AK, Leiden

AI Labs are collaborations of Leiden University with external parties such as industry, governmental parties and other universities on the topic of Artificial Intelligence. The Science institutes of Leiden University are unique located in the largest Bioscience Park of the Netherlands, next door to…

Lipsius, Cleveringaplaats 1, 2311 BD, Leiden

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

On 14 November 2019, Luis Fiallos Pazmino defended his thesis 'Legal Perspectives on the Cross Border Operations of Unmanned Aircraft Systems'. The doctoral research was supervised by Prof. P.M.J. Mendes de Leon and Prof. E.C.P.D.C. De Brabandere.

Wijnhaven, Turfmarkt 99, 2511 DP, The Hague

Promotors: Prof.dr. P.G.L. Klinkhamer, Prof.dr. P.M. Brakefield

Over the last decades, aviation safety has improved strongly. As a downside, airline pilots do not have as many opportunities to develop through experience the competencies that they need in critical situations.

G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

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In the Master’s programme in Bio-Pharmaceutical Sciences of Leiden University you are trained for a scientific career in drug research and development.

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

In times of hardships or crisis, local people know how to deal with it using their resourcefulness. Although efforts are sometimes made by the government to help them, they are fully aware that community support is at least equally important.

Source: Nature Biotechnology, Volume 2014, Issue June (2014)

Due to the modern techniques of combinatorial chemistry and high-throughput screening, data on the biological activity of many millions of compounds is known. However, it is still very difficult to transfer this data into knowledge: if we know that compounds A and B bind to a certain protein with high…

Dr. at the Department of organic chemistry, Wageningen University - the Nederlands

At the moment, over 350.000 chemicals are registered worldwide for production and use. Their application, however, may harm human health and the environment.

Promotor: A.P. IJzerman Co-promotor: L.H. Heitman