Smooth platinum electrodes roughen and wear when subjected to repeated cycles of oxidation and reduction, which causes nanometer-scale mounds to grow. Leiden chemists Leon Jacobse and Marc Koper, together with physicist Marcel Rost, discovered the exact details, using a unique tunneling microscope.

What do you do when you get the chance to meet Nobel Prize winners in your field? You say ‘yes’, of course! Two young chemists from Leiden had the opportunity to attend the Nobel Laureate Meeting in Lindau, Germany. They share what the experience was like.

A month ago it was Marc Baggelaar, and now Hans Kistemaker too has obtained his PhD cum laude at the Leiden Institute for Chemistry (LIC). ‘He has made ground-breaking contributions to the world of protein modification,’ says PhD supervisor Gijs van der Marel. Kistemaker obtained his PhD on 11 May…

Leiden PhD student Xuequan Zhou has designed a new promising molecule that efficiently kills cancer cells, but does not harm healthy tissue. The trick: the drug is only active when irradiated with light. Zhou’s new compound does this extra efficiently by cleverly self-organising into nanoparticles.…

Researchers from the THEOR CHEM group at Leiden University strive to set new benchmarks in the accuracy of the prediction of interaction energies between molecules and metal surfaces.

While there are numerous and extremely advanced methods to sequence the genome, only a few methods exist to sequence the proteome. The Vidi project of Grégory Schneider promises to shed light on the most difficult paradigm of proteomics: achieving an error-free determination of the sequence of single…

Storing energy is one of the biggest challenges in the energy transition. Hydrogen could be a solution. Chemist Daan den Boer is researching how to make the chemical reaction needed to store energy in hydrogen as cheap and efficient as possible.

A catalyst: normally a substance that speeds up a chemical reaction, without adding molecules to this reaction. Scientists from the group of Prof. Marc Koper of Leiden University and Prof. Yang Shao-Horn of MIT now discovered that in specific reactions that need oxygen, catalysts called metal oxides…

Chronic pain, nausea or vomiting due to chemotherapy. If you suffer from such ailments, medicinal cannabis can be a godsend. Though a downside is that it can make patients high. Therefore, Leiden researchers from the Oncode Institute are investigating alternatives that do not make you high. In Nature…

Dr Bela Bode receives a Feodor Lynen research fellowship for postdoctoral researchers by the Alexander von Humboldt-Foundation for development of new methods for signal enhancement in solid state NMR. He aims to create a specific analytical tool for surface studies and research on membranes and membrane…

Electrocatalysis will play an increasingly important role in future in the transition to more sustainable energy. Thanks to chemist Isis Ledezma Yanez, we now know more about the hydrogen evolution process. PhD defence on the 9th of June.

Professor Joanna Aizenberg (Harvard University) is the recipient of the 2017 Havinga Medal. She is awarded for her eminent and original contributions to the field of biologically inspired materials science.

Nerve pain is one of the most common side effects of chemotherapy. It is therefore one of the biggest reasons for cancer patients to stop treatment early. Darcy Reynolds worked on new drug candidates against this pain during her bachelor's thesis. She developed a new series of molecules that increase…

Where exactly on the surface of a catalyst do the chemical reactions occur? Until now, it has always been a challenge to identify the exact locations of these ‘active sites’. In a new article in Nature, Leiden chemists helped their international colleagues reveal new insights into this issue. Their…

PhD student Thierry Rohmer received the Ernst Award 2009 of the Gesellschaft Deutscher Chemiker (GDCh) for his publication in the Proceedings of the National Academy of Science of the USA on the structure-function relation of the photoreceptor phytochrome. The prize was presented at the Annual Discussion…

Professor Michiel Kreutzer has been appointed as Dean of the Faculty of Science at Leiden University. He will take up the role on 1 January 2020. At present, he is Head of the Department of Chemical Engineering and Director of Education at the Faculty of Applied Sciences at Delft University of Technology.…

In the programme NWO Open Competition Domain Science - GROOT, twenty new consortia will start a large research project. This boost of more than 47 million euros will make new research possible in the science domain. Among the winners is the Nanoscale Regulators of Photosynthesis consortium in which…

A group of chemists, that includes Sander van Kasteren and Hermen Overkleeft, has discovered that azides, a certain type of chemical compound, can determine whether or not T cells respond to or ignore a vaccine. Their discovery is set to be published in Angewandte Chemie.

The monthly ILS Lunch Seminars present the perfect opportunity to unite the different Institutes situated within Leiden Law School. On Thursday 14 March 2019, the next edition of the ILS Lunch Seminars will take place. This time, Nienke van Heek and Esther van Ginneken will present their research.

On International Women’s Day 2020, the first edition of the Leiden Top 50 was revealed, a list of 50 women who made a difference in Leiden in 2019. Among them three women from our Faculty: Martina Vijver, Felienne Hermans and Irene Groot.

Not one, but two Olympic rowing medals with a Leiden-Delft touch. Master student Life, Science and Technology Stef Broenink won silver in the double pair. He and partner Melvin Twellaar were in front for a long time, but were overtaken by the French at the last minute.

Leiden University is part of a Dutch consortium that will receive 4.7 million euros from NWO to build a facility that makes controlled, thin layers of material. The facility can produce small and large films, something that is globally unique. And that is key to scaling up, for example, new catalysts…

From children’s inability to identify animals to a big protest at the opening of the academic year: below are some of our most popular articles of 2019.

How do our cells keep DNA stored away? To find out, biochemist Remus Dame received a 3 million euro Science-Groot grant. Leiden University will share the grant with TU Delft, VU Amsterdam and the Hubrecht Institute.

The first phase of the construction of the new building for the Faculty of Science is finished. The Cell Observatory of the Institute of Biology Leiden will be moving to the new building on the 19th of May.

Dana Rademaker has won the Unilever Research Prize, which she received together with 2,500 euros at the Unilever’s Foods Innovation Centre on 12 December. She received the prize for her master’s thesis, which she wrote last year for the master’s programme Chemistry.

The construction of the new building for the Faculty of Science is in full progress. The Cell Observatory of the Institute of Biology Leiden will be moving to the new building in the beginning of 2016. Professor Annemarie Meijer and Dr. Marcel Schaaf had a sneak preview.

On January 24 Professor Annemarie Meijer and Dr Sander Wezenberg received a NWO grant for their research. The grant was awarded within the Open Competition Domaine Science-M programme and is intended for innovative research areas that can form the basis for the research themes of the future.

Professor Geert de Snoo, Dean of the Faculty of Science at Leiden University, has been appointed Director of the Netherlands Institute of Ecology (NIOO-KNAW) with effect from 1 November 2019. He will stand down from his role as Dean of the Faculty of Science with effect from 1 September. De Snoo will…

Biophysicist Anjali Pandit has been awarded a FOM 'Projectruimte' research grant for her proposal ‘Tuning into the photosynthetic membrane with atomistic precision’.

A semi-empirical version of the specific reaction parameter approach to density functional theory (SRP-DFT) has been remarkably successful at predicting dissociative chemisorption probability vs. incidence energy curves for reactions on metal surfaces. New quantum Monte Carlo (QMC) calculations on the…

Chemical biologists from Leiden, led by Dr Mario van der Stelt, have discovered substances that can reduce inflammation processes in the brain. This is a first step in the development of potential medicines for the treatment of brain diseases like Alzheimer's and Parkinson's. Published in Proceedings…

Researchers led by Professor of Chemistry Marcellus Ubbink have recently published a study in Proceedings of the National Academy of Sciences (PNAS) about the dynamics of an important redox enzyme. This work was accomplished thanks to an NWO VICI subsidy granted to Professor Ubbink.

Surface Reaction Barriometry: Methane Dissociation on Flat and Stepped Transition-Metal Surfaces.

Professor of Developmental Biology Christine Mummery and chemist Dr Dennis Hetterscheid have each been awarded an ERC Proof of Concept grant. These grants are to explore the societal potential of ideas generated in previous ERC-funded projects.

Using N2 dissociation on Ru(0001) as a representative showcase (for catalysts employed in the Haber-Bosch process), we have shown for the first time that non-adiabatic effects can substantially reduce a molecule’s dissociation probability on a metal surface. These effects are currently completely unaccounted…

Chemist Sylvestre Bonnet has received a Proof of Concept grant from the European Research Council (ERC). With the grant of 150,000 euros, Bonnet will investigate whether chemotherapy that is activated by light can be used against eye cancer.

Nathaniel Martin has been appointed professor in the field of Bioorganic Chemistry within the Faculty of Science at the Institute of Biology Leiden, starting from 1 March 2018. His research focuses on using new (bio)chemical approaches to combat infectious disease, as well as on developing new molecular…

As fruit and vegetables ripen, ethylene gas is released. Ethylene also influences the speed at which they ripen. Chemist Tom van Dijkman studied how small and inexpensive sensors can be made that measure ethylene concentrations during transportation. PhD defence 12 May 2016.

The winner of the 2022 Spring edition of the NWO Venture Challenge was announced during the Dutch Biotech Event. The innovative startup Iprotics has developed specific proteasome inhibitors that potentially treat multiple myeloma (MM) without the side-effects known from traditional proteasome inhibi…

Marc Koper, Professor of Catalysis and surface chemistry, has won the Brian Conway Prize for Physical Electrochemistry of the International Society of Electrochemistry (ISE). The ISE jury chose Koper as the winner due to his outstanding contributions in the field of physical electrochemistry.

As a student in the MSc Chemistry programme offered by the Leiden Institute of Chemistry (LIC) you will focus your studies on one of the two main research areas of the LIC. Students in the research area Chemical Biology will study fundamental biological and biomedical problems to understand physiological…

The surface and the edges of graphene are expected to provide higher sensitivity and specificity in detecting and characterizing single molecules. However fundamental physical limits exist in reaching an ultimate precision in detecting the dynamics of chemical and biological systems. The research in…

Imagine we could do what green plants can do: photosynthesis. Then we could satisfy our enormous energy needs with deep-green hydrogen and climate-neutral biodiesel. Scientists have been working on this for decades. Chemist Chengyu Liu will receive his doctorate on 8 June for yet another step that brings…

An interdisciplinary team of Leiden researchers has discovered that wasting syndrome, a severe byproduct of tuberculosis, is the same for all humans and animals studied. The discovery offers new opportunities to investigate the still insufficiently understood condition. The scientists also developed…

Professor Marc Koper researches how you can use electrical energy to make or break chemical bonds. He has just been awarded a Spinoza Prize, the Netherlands’ highest personal science award, for his fundamental research into how this form of electrolysis works.

How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…

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