Our team is committed to the study of knowledge in its broadest sense, encompassing both ideas and practices in all its historical variety. We look at what people regarded as knowledge, how they created, collected, circulated and used it, also why it mattered to them, and how all this was embedded in…

The Around the Rapenburg walk takes you along the canal where Leiden University was founded 450 years ago.

The objective of this study is to better understand the distribution of microplastics in the environment. More specifically, we will quantify the abundance and distribution of microplastics on beaches.

Rector Magnificus Carel Stolker will retire on 8 February. If there’s one theme running through his career, it’s the links between the University and society. In this series of pre-retirement discussions, Stolker will talk one last time to people from within and without the University. This edition…

Study information, LUC 101 | Information Session

The new book by Dimiter Toshkov - associate professor of Public Administration at the Faculty of Governance and Global Affairs - has been recently published by Palgrave Macmillan.

Home to the International Court of Justice and the International Criminal Court, The Hague is the perfect backdrop to explore conceptions of justice in our global society. Questions of human rights, peace, security and the environment present legal and policy challenges for governmental and non-governmental…

The World Politics Major at Leiden University College The Hague examines the big ideas and the powerful forces – political, military, economic, social and cultural – that shape the world at every level, from the global to the local and everything in between. Political conflict is a key driver of many…

Leiden University Medical Center (LUMC) and the Centre for Human Drug Research (CHDR) are taking part in the phase 2 clinical trial of Janssen Vaccines’ candidate coronavirus vaccine. The vaccine will be tested on 45 test participants in Leiden from 14 September onwards.

Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.

You’ve been accepted! Leiden University looks forward to welcoming you as a new student. Your next step is to prepare for your studies. Below you can find some tips to help you get a head start as you embark on your studies at Leiden University.

This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…

In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

Promotor: H.S. Overkleeft, Co-promotor: B.I. Florea

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea

Can Cyanobacteria be engineered to convert the greenhouse gas carbon dioxide into the valuable chemical isoprene?

Leiden University offers you several services related to career orientation and job application skills.

Leiden University offers you several services related to career orientation and job application skills.

Leiden University offers you several services related to career orientation and job application skills.

Glycosidases are essential in fundamental biological processes and are responsible for the degradation of most (oligo)saccharides, glycolipids and glycoproteins.

This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…

Leiden University offers you several services related to career orientation and job application skills.

Leiden University offers you several services related to career orientation and job application skills.

More attention for internationalisation, diversity, but also the mental health of students: that’s what Marleen van Dorst would like to see change. As of 1 September, she will be the new assessor of the Faculty of Science.

This PhD project investigates how automatic sign language recognition technology can be further developed to analyse static images and textual descriptions of signs.

Is scientific research useful? In his dissertation, Jorrit Smit argues that in order to answer this question one should not look at, for example, prominent scholars or influential organisations, but at places where knowledge exchange and co-creation take place. Promotion 6 May.

With the long lockdown, it’s been a hard year for Leiden businesses. How can the local economy bounce back and how can the University help? Two talk shows discussing this were recently recorded in the Academy Building. They will be aired on Unity TV on 28 September and 12 October.

This thesis describes the development of a variety of mannosylated conjugates. Antigen presenting cells bear mannoside recognizing receptors that actively transport antigen into the cell. This thesis exploits this feature for the development of improved vaccines.

This Thesis describes the synthesis of D-alanylated ribitol-based wall teichoic acids from S. aureus to probe their interaction with immune-binding partners.

Are you interested in combining your Science master programme with the Education specialisation? Learn more and watch the introduction video.

Leiden University was founded in 1575 and is one of the leading international research universities in Europe.

An overview of our infrastructure at the SPP division:

Research on heredity and diseases is simply not possible without programmers. Curious about how you can use your IT and biology skills to deal with real-life sickness and health problems? If so, Bio-Informatics in Leiden could be something for you.

How do processes of coalition-formation influence patterns of decision-making in the European Union?

The Leiden wall formulae, Einstein's sink or the signature wall of Ehrenfest. It are just a few of Leiden's hidden science treasures. Alumnus from the Leiden Observatory Alex Pietrow described a few of these places on travel website Atlas Obscura.

Taxonomy as a science has accumulated data and knowledge for more than 250 years.

How we think about and act on the usefulness of scientific research has epistemological and political implications: what knowledge consists of, how it comes about and to what ends. In this dissertation, I situate the usefulness of scientific research in concrete places for knowledge exchange. The exchange…