Contact Macromolecular Biochemistry

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Our teaching is characterised by individual attention for students, contact with diverse cultures and innovative teaching methods. Personal supervision and the binding study advice contribute to our success. Our teaching and research are closely interwoven.

We are aiming to develop novel technologies to allow better sample preparation or coupling of analytical methods to (i) analyse ultra small samples, (ii) to analyse more metabolites in a quantitative manner and/or (iii) increase the sample throughput.

This Thesis describes the synthesis of D-alanylated ribitol-based wall teichoic acids from S. aureus to probe their interaction with immune-binding partners.

Our institute contributes to multiple curricula. 

Prehistory of Amazonia seen from the kitchen

Our institute contributes to multiple curricula. 

This publication is written in Dutch. Please consult the Dutch page for more information.

The aim of this thesis was to develop aluminium salt-based nanoparticles that may ultimately be used as adjuvant in human vaccines.

All living systems are assembled from nature’s repertoire of small, medium, and large organic molecules. This theme focuses on the study, discovery and development of novel bioactive compounds obtained from biodiversity. We aim for new insights into the role of these molecules in the natural environment,…

In dit onderzoek van de Universiteit Leiden kijken we hoe vaders en moeders de zwangerschap en de overgang naar het ouderschap ervaren.

An analysis of researchers' global mobility reveals that limiting the circulation of scholars will damage the scientific system.

Are you a journalist, public administration practitioner or (academic) researcher with a question related to our expertise? Are you looking for a speaker, presenter or trainer for your specific event or knowledge needs?

As part of Nexus 1492 Subproject 4: A Future for Diverse Caribbean Heritages, which seeks to shed light on how local communities interpret and engage with heritage in the present day, this doctoral study aims to gain insight into how indigenous heritage is represented in the school curriculum for social…

Tuberculosis (TB) is associated with 1.5 million deaths annually. There is a need exists to optimize both current as well as novel antibiotic combination treatment strategies to improve the effectiveness and safety of treatments against TB.

LUCIS publishes two peer-reviewed book series, “Leiden Studies in Islam and Society” (Brill) and “Debates on Islam and Society” (Leiden University Press).

Collaboration is increasingly common among teachers in schools. As such, teacher education should prepare prospective teachers to effectively interact with other teachers in different types of communities or groups.

This thesis focuses on the development of sample-preparation methods for small amounts of samples and applying the developed methods to muscle tissues to investigate the mechanisms involved in sarcopenia.

Viral diseases constitute one of the major challenges in modern medicine. Membrane-targeting have broad-spectrum potential and could distinguish viral membranes from the host cell plasma membrane by the difference in membrane curvature.

Contact Medical Biochemistry

Our public programme includes lecture series, conferences, visiting fellowships, panel discussions and many other interesting events. Have a look at what we've organised in the past years.

The GMP Facility facilitates development and production of Advanced Therapy Medicinal Products (ATMPs) and chemical (peptide) synthesis.

Leiden Institute of Physics regularly has vacancies for staff, postdocs, and PhD positions.

We are a diverse collective with members from different faculties and organisations. Select a faculty or organisation in the left column to search and connect with members. Have questions or want to become a member? Get in touch with the steering committee.

The Maker Space in Huizinga 0.11f is a creative environment where students and researchers can access a professional 3D scanner, 3D printer, and a camera-based scanning system for high-quality text and image digitisation.

From development of nanomaterials to advanced instrumentation and smart software systems, this specialisation empowers students to become a key player in tomorrow’s technological breakthroughs—through interdisciplinary research, industrial collaboration, and innovation-driven learning.

The Reinforcement Learning lab conducts research into Reinforcement Learning and Intelligent Combinatorial Algorithms.

This publication is in Dutch. Please consult the Dutch page.

Within this thesis the central stage is taken by the discovery and investigation of transglycosylation of sterols. First, investigation focuses on the development of a method to accurately detect and quantify glucosylated metabolites in biological materials.

Op deze pagina vind je de internationale universitaire netwerken waar de Faculteit der Rechtsgeleerdheid deel van uitmaakt.

To improve treatment of breast cancer patients it is important to understand all stages of breast cancer from initiation to in situ disease and progression to invasive disease. In this thesis we use intraductal injections of patient derived tissue to model ductal carcinoma in situ and invasive breast…

This thesis describes the development of a variety of mannosylated conjugates. Antigen presenting cells bear mannoside recognizing receptors that actively transport antigen into the cell. This thesis exploits this feature for the development of improved vaccines.

The adsorption of D2 and CO2 on catalyst surfaces is studied using a molecular beam in ultra-high vacuum.

The Leiden Science Run is a 5 km charity run at the Bio Science Park Leiden. It is a relay race organized by Leiden University in collaboration with the University Sports Centre.

This publication is in Dutch. Please consult the Dutch page for more information.

Here you will find articles written by and about the Brave Little Ones research group.

This thesis describes research aimed at discovering inhibitors selective for either of the two endoplasmic reticulum α-glucosidases, ER-I and ER-II, with the overarching goal of discovering new antiviral agents to treat viruses that rely on host N-glycosylation for proliferation.

How can we develop a new microscope that can distinguish individual atoms in proteins?

On this page you will find output produced as part of the project and resources related to this research project.

The SSH Sector Plans are a national initiative in which Dutch universities collaborate to strengthen research and education in the social sciences and humanities.

Are you a journalist, public administration practitioner or (academic) researcher with a question related to our expertise? Are you looking for a speaker, presenter or trainer for your specific event or knowledge needs?

Members of our research team give different types of presentations and lectures.

What is the effect of practicing with electronic books on reading skills for grade 1 students?