Research aims: Identification of key genes involved in programming the cellular architecture of A. niger & Genetic engineering of A. niger in order to improve its secretory capacities and rheological behavior under industrial fermentation conditions.

Can the conditioning paradigm be used for checkpoint inhibition cancer treatment?

PBDL favors multidisciplinary research. Depending on the problems under investigation, PBDL establishes collaborations between experts from for example molecular genetics, molecular and electro cell physiology, biochemistry, organic chemistry, analytical mathematics, mathematical statistics and computational…

The Co-Align Conference 2023 will be held on 16 May 2023 at Leiden University.

Our Master Law in European and International Human Rights Law (LL.M.) looks at the various human rights protection mechanisms from a comparative perspective

This project tries to explain the persistence of this cultural repertoire by zooming in on (1) interaction between idioms (cultural repertoires) available to scholars at certain points in time, (2) mechanisms that help transmit repertoires across time and place, and (3) rhetorical purposes for which…

What is dark matter? How do supermassive black holes form? ‘Primordial’ black holes might hold the answer to these long-standing questions. Leiden and Chinese cosmologists have identified a new way in which these hypothetical objects could be produced just after the Big Bang. Publication in Physical…

PhD defence

Conference

Promotor: J.W.M. Frenken, Co-Promotor: R. Felici

In vitro disease models play a fundamental role in drug research. They enable the systemic identification and validation of disease mechanisms and the discovery of possible drug targets. However, more than often, drug candidates that are identified in vitro fail in the later clinical stages of drug…

M.T.M. Koper, Co-promotor: D.G.H. Hetterscheid

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

Formulation of biopharmaceuticals

Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea

Our institute aspires to be the center of excellence for strategic and quantitative research and education on sustainable use and governance of natural resources and biodiversity. We have two distinct research programmes: Environmental Biology and Industrial Ecology. The department of Industrial…

To design the ideal water oxidation catalyst, understanding of the catalytic mechanism and decomposition pathways is essential.

Ecotox is a stimulating top-facility that provides an integrative research environment around the topic of ecotoxicological testing and experimental research. Research focus: Dose-response modelling Mode-of-actions and mechanism-of-actions Test method development, in view of targets in AOPs (adverse…

With the rise of multi-drug resistant bacterial pathogens, the possibility of a post-antibiotic world is quickly becoming reality.

Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…

Plant Sciences' contribution to the Development & Disease research theme is to unravel the processes that allow plants to adapt to changing abiotic and biotic environmental conditions or stresses, with the aim to contribute to the sustainable production of food, flowers and bio-based products using…

This project has two main aims: I. Determine when novelty promotes fear extinction. II. Discover the neurobiological mechanisms underlying these effects.

Promotor: P.M. Brakefield

Read all about YAL membership and the members of the Young Academy Leiden.

How to contribute to a quantum leap of eco-industrial symbiosis in China?

From the largest numbers to the smallest molecules and from the oldest galaxies up to the latest algorithms, explore our standout discoveries and most inspiring collaborations from the past year!

How can we improve quality of life and study success in young, high-functioning adults with autism?

Which traits did change due to the invasion process of plants and how do these traits contribute to the invasiveness of such species. What is the role of carbohydrate accumulation? What is the function of carbohydrate accumulation in plants? Is genetic variation depleted in invasive species under se…

NETHATE is a Marie Skłodowska-Curie Actions (MSCA) project seeking to investigate the roots, societal impact and mitigation strategies of hate in offline and online foras.

Our DNA molecules are packaged by proteins in compact structures. The aim of this project is to understand how modern gene editing techniques nevertheless get access to their target in the DNA.

Cognitive enhancement reflects the use of any (legitimate) means such as for example food supplements to reach one’s personal best.

Can a newly developed, app-based, personalized maintenance program enhance the effectiveness of the exposure-based one-session-treatment for children with a specific phobia?

What are the genes and molecular mechanisms involved in bacteria-mediated plant drought tolerance?

During the Leiden Science Family Day, you will visit places that are normally closed to the public: go backstage at the Faculty of Science!

Biosynthetic gene clusters (BGCs) for natural products are widespread in microbial genomes, and they are rapidly exchanged. This research assesses the factors that control the spread of BGCs and resistance genes in nature. This includes risk assessment for the spread of engineered DNA in nature.

This research area is focused on the development and application of novel concepts and models in the emerging area of quantitative systems pharmacology (QSP).

What are the global relationships between environmental conditions and abundance of distinct types of mycorrhizal fungi in soil and plant roots?

This research programme aims to increase the scientific understanding of how current and emerging anthropogenic threats affect biodiversity and ecosystem services to facilitate strategic management of natural resources. To this end, we address urgent challenges in relation to the mechanisms involved…

Synthetic cells, also known as artificial cells or protocells, have wide ranging applications from drug delivery vectors to cell models. In biotechnology they can function as micro- or nanoreactors with possible applications in biocatalysis and photocatalysis. Phospholipids are by far the most commonly…

Research at the BIOSYN group is comprised of the following research themes:

Can chemical safety assessment be improved with zebrafish embryo-based reporter assays?

Interested in the programme overview of European and International Human Rights Law? Please take a look at this page. The programme information is listed.

The Minor Computational Approaches to Disease, Signaling and Drug Targets (CADSDT) is focused on fundamental scientific research required for discovery of new drug targets and development of new drugs.

This study, Calypso, The Trinidadian Experience, has sought to establish links between calypso music and the construction and maintenance of identities, and to locate the genre as a mechanism (or as part of a broader mechanism) that has exerted on-going social influence within Trinidadian society…

The Center for Interdisciplinary Placebo Studies Leiden (IPS) aims to advance the understanding of placebo and nocebo effects, their underlying mechanisms, and their potential applications in clinical practice. IPS consists of a group of interdisciplinary researchers working at Leiden University with…

The research master's specialisation Cognitive Neuroscience consists of five main parts: the general courses, the track-specific courses, the elective courses, a research internship and a thesis.

PhD defence

Emeritus professors Dirk van Delft and Frits Berends both channelled their inner Sherlock Holmes as they delved into the life and work of the great physicist Hendrik Lorentz. Their voluminous biography ‘Lorentz: gevierd fysicus, geboren verzoener’ (Lorentz: celebrated physicist, born mediator) is published…