Does a universal psychoeducational course about stress in adolescents: I) lead to an increase in knowledge of stress?, II) affect the frequency with which stressors are experienced and the overall stress level?, III) create interest in a tier 2 level follow-up training?, and IV) appeal to students in…

On the 4th of November, Aliza successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Aliza on this achievement!

The research group of Semonti Bhattacharyya at the Leiden Institute of Physics studies quantum transport measurements in Van der Waals heterostructures.

Erik de Maaker, B. Ramila, Maaike Feitsma, Mayke Groffen, Ellen Haeser, Rachel Lee, M. Karthika, Leonie Sterenborg and Sanne van den Dungen

Multicopper oxidase, laccase, can efficiently reduce oxygen to water and are mostly used in the enzymatic biofuel cells.

The Biomedical Metabolomics Facility Leiden (BMFL) is the core metabolomics facility of Leiden University and the Metabolomics and Analytics Centre (MAC). We offer a highly structured environment for advanced MS-based metabolomics studies and build on fully validated, state-of-the-art assays that each…

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

How does task context affect children’s word productions?

Can the offering of host community compensation help to prevent or solve siting controversies, and if so, why and under which conditions?

Promotor: Prof.dr. G.J. Kroes

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PathOS aims to contribute to a better understanding and measurement of Open Science impacts and their causal mechanisms. This is pivotal in order to develop effective OS policy in the EU (European Union). It will do so by collecting concrete evidence of OS effects, by studying the pathways of OS practices,…

This article studies the perceived legitimacy of EU enforcement actions.

The research project examines the site-specific event within the field of installation art and choreographic practices.

Our scientists working with laboratory animals undergo training on animal experiments. In this training, researchers learn how to handle laboratory animals responsibly. Read more about the requirements we set for researchers working with laboratory animals.

This proposal aims at the construction of a comprehensive and authoritative scientific grammar for Dutch and Frisian in the form of a virtual language institute: het Taalportaal/the Language Portal.

This dissertation examines what network in the human brain is involved in the perception of prosody and whether activity within this network is modulated by the personality trait alexithymia.

Although sexual abstinence before marriage is no longer the central message in The Netherlands the affective relationship as a criterion for professionals within criminal justice can be seen as a more contemporary version of marriage.

Worldwide resurgence of pertussis necessitates the need for improvement of pertussis vaccines and vaccination strategies.

This project proposes an integrated and comparative study on the syntactic, semantic, prosodic and processing aspects of in-situ wh-questions, taking the Grammar-parser correspondence hypothesis (Phillips 1996, 2003) as a guiding principle.

The project will support Responsible, Research and Innovation (RRI) policy experiments in the healthcare sector in three European territories: in Murcia (ES), Örebro (SE) and the Republic of Cyprus (CY). CHERRIES will engage the territorial stakeholder ecosystems in participatory agenda setting, need…

The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…

Empirical and experimental research focusing on literary, legal, medical and audiovisual translation.

The

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

This project aims at investigating the syntactic role of focus in ellipsis across languages.

Information for prospective, current and international students

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

How do technologies of computer vision, which promise to replace humans in the understanding of images, work in practice in the field of security, and what are their ethical and political implications?

This project examines how speakers store and process regular pitch variation.

The presents thesis investigates the extent to which Chinese, Dutch and American speakers of English are mutually intelligible. Intelligibility of vowels, simplex consonants and consonant clusters was tested in meaningless sound sequences, as well as in words in meaningless and meaningful short sent…

M. Danhof, Co-promotor: O.E. Della Pasqua

In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

The Division of BioTherapeutics at the Leiden Academic Centre for Drug Research (LACDR) is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.

Source: Br. J. Pharmacol., Volume 172, Issue 3, pp. 940-55 (2015)

The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets

A seven-metre glass tunnel, filled with running water, and equipped with speakers and cameras. An artificial river for investigating what light and sound pollution do to migrating fish.

Beneficial plant-associated microbiota, particularly those inhabiting the rhizosphere, contribute substantially to plant health through pathogen suppression, stimulation of plant defence responses, and enhanced nutrient acquisition.

A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.

Kantorowicz explores how gender stereotypes affect perceptions of leadership competence across crisis types, focusing on pandemic leadership traits.

In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.

The research in Biological- and Soft-Matter Physics specialisation consists of 120 European Credit Transfer System (EC) points and includes electives (60 EC) and two research projects (60 EC).

The two-year master’s programme in Computer Science at Leiden University offers seven specialisations ranging from AI to Bioinformatics and Data Science. The programme combines excellent theoretical teaching with possibilities for applied work with industrial relevance.

This webpage is for companies interested in becoming an internship partner.

Metastasis is responsible for over 90% of cancer-related deaths and arises from the ability of a small subset of tumor cells to detach from the primary tumor, overcome multiple biochemical and mechanical barriers, disseminate through the body, and colonize distant organs.

Around 1.8 million years ago, early hominins moved into Eurasia and adapted to colder climates and unfamiliar ecosystems. This project investigates whether innovations in diet such as eating new plants or applying new techniques for food processing (cooking or fermentation) contributed to this major…

De inschrijvingen voor de Keetje Hodshon Prijs zijn geopend. In 2023 is de Keetje Hodshon Prijs bestemd voor onderzoek op het gebied van de Historische wetenschappen, als aanmoedigingsprijs voor onderzoekers die in 2018 of daarna gepromoveerd zijn. Voordrachten dienen digitaal te worden ingediend uiterlijk…

To mark Leiden University’s 450th anniversary, this exhibition pairs historic photographs with contemporary research. Seven ‘Then & Now’ diptychs show how the Institute of Physics blends a rich past with cutting‑edge science.