Coordination chemistry is the chemistry of metal atoms

The Faculty of Science

NL-BioImaging AM is a distributed research infrastructure aimed at promoting progress in the most cutting edge microscopy technologies and providing open access to these technologies to a broad community of academic and industrial users. All Netherlands bio(medical) microscopy centers participate.

Organisation Institute of Biology Leiden

Hui Deng (MSc.), a PhD-student in the department of Molecular Physiology, has received an award for the best oral presentation during the 26th International Cannabinoid Research Society (ICRS) conference with more than 300 participants in Bukovina, Poland. Hui Deng presented her work on “Rapid and…

Mario van der Stelt (Head of the department of Molecular Physiology at the Leiden Institute of Chemistry) has received the Young Investigator Award from the International Cannabinoid Research Society during the annual meeting of the society in Montreal, Canada. The Young Investigator Award was given…

Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.

Through his project we will unravel the global regulatory networks that control gene expression in Streptomyces bacteria and allow them to properly respond to major changes in the environment; we will then harness this knowledge to activate and identify novel antibiotics

Can Zebra finches learn to distinguish two very similar Dutch words? Research by behavioral biologist Verena Ohms proved that they can identify 'wit' and 'wet'. Ohms published her findings in

The Molecular Physiology group collaborates with both international public-private and academic institutions.

There are several training oportunities within the cell observatory

Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…

These are the staff members of the Leiden - Latin America and the Caribbean Centre

Multicellular giant algae Chara species have been widely used in physiological studies for decades.

Student project opportunities at the MolPhys group

The imaging group focuses on bio-imaging, image analysis and visualization.

Contact information & address

The probability for dissociation of molecules on metal surfaces, which often controls the rate of industrially important catalytic processes, can depend strongly on how energy is partitioned in the incident molecule. There are many example systems where the addition of vibrational energy promotes reaction…

Neuraminidases are enzymes that cleave glycosidic linkages of sialic acid. These enzymes are involved in influenza infections as well as in many cellular processes in mammals and micro-organisms.

Microbial Sciences' contribution to the Biodiversity & Evolution research theme focuses on understanding how bacteria sense and respond to their environment, and how bacterial diversity and evolution is influenced by cooperative and antagonistic interactions taking place between microbes.

A delegation from Leiden University will be visiting Mexico from 21 to 25 October. The visit aims to strengthen the ties between Mexican universities and Leiden University.

Tracking mucus-eating bacteria, mapping the complexity of planetary nebulae and a signalling pathway in cancer. These three Leiden projects have been awarded Open Competition Science-M funding by the Dutch Research Council.

With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…

PhD defence

Overkleeft

The challenge: Building a tool to detect chemical compounds that individually cause non-lethal stress to bacteria, but that are lethal in combination. A team of thirteen Leiden students are taking up this challenge in the annual ‘international Genetically Engineered Machine’ (iGEM) competition for applications…

Is it possible to diagnose diseases using molecular switches? The new international consortium LogicLab will address this question. Leiden chemist Sylvestre Bonnet and Leiden pharmacologist Thomas Hankemeier are involved in the project. LogicLab will run for four years and will receive over 3.5 million…

The dissociative chemisorption of a molecule on a transition metal surface represents a rate-limiting step in many heterogeneously catalyzed processes, whereby most chemicals are made. In spite of the importance of this reaction, an accurate first principles approach to modeling it does not yet exist.…

To be eligible for Chemistry at Leiden University, you must meet the following admission requirements.

Lecture

The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.

Professor Eline Slagboom has been studying multiple generations of families for over 20 years. She collects data on why some people age healthily and others decline early.

Lecture

PhD defence

The rare Ethiopian wolf is increasingly coming into contact with local cattle farmers. PhD candidate Girma Eshete explored ways of saving this elegant animal from being wiped out. Phd-defense on 5 September.

Are you interested in taking up an extra challenge during your master’s programme?

Cancer is the leading cause of death in the Netherlands, and, with over 100 different types of cancer, it’s not a simple disease. Today, skin, breast, lung, prostate and colon cancer are the most diagnosed forms. Therefore, the discovery and development of new drugs has the ability to significantly…

Chemical reactions go hand-in-hand with an energy exchange with the environment in which they take place. Surfaces offer a variety of energy dissipation channels, constituted by the nuclear and electronic degrees of freedom of the atoms at the interface. Aiming at an improved future harvesting of energy,…

This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Science with University of California.

Supervisor: Natalia Ortiz Zacarías

Are you interested in taking up an extra challenge during your master’s programme?

Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.

Annelot van Esbroeck-Weevers, PhD student at the Molecular Physiology research group at the Leiden Institute of Chemistry, headed by Dr. Mario van der Stelt, has been awarded the Best Oral Communication Prize at the 8th European Workshop on Cannabinoid Research, held from 31 August to 2 September 2017…

Anthe Janssen, a PhD student in the Molecular Physiology research group of Prof. Mario van der Stelt, has been awarded the Public's Choice Prize for Best Oral Presentation during the Young Medicinal Chemist Symposium '18 in Ljubljana, Slovenia.

Lecture