Mechanobiology is a major area in biology, however, mechanics is currently a missing element in drug development pipelines. This has led to a high cost for the society. Mechanotoxicity of drugs often appears as a long-term side effect of drugs, and has led to removal of drugs from the market. Furthermore,…

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…

Promotores: F.H. van Lunteren, F.P. Israel

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: Prof. dr. V. Vitelli

On this page you can find the current vacancies at the Van der Molen research group.

To study how planetary systems come into existence we study much younger systems still in formation.

This PhD-research is conducted to test the hypothesis that Gutenberg and consorts developed a standardised and even unitised system for the production of textura type, and that this system was extrapolated for the production of roman type in Renaissance Italy.

This dissertation revolves around the design and implementation of novel instrumentation and related measurement techniques, at the single molecule level, for use in biophysical research. Chapter 1 presents an introduction to the field of fluorescence-based single molecule measurements. In particular,…

A dense region of a gaseous and dusty cloud collapses to form a protostar surrounded by a disk and an envelope. This thesis uses both observations and models to study physical and chemical conditions of these protostellar systems which are likely where planets start to form.

This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.

In this thesis, we have studied the potential of the zebrafish larval model in studying the ECS, as a complementary model to the existing rodent models.

A large diversity of exoplanetary systems has been found, but it is still unclear what drives this diversity.

The CMCB brings together a diverse range of unique expertise in microbial cell biology. Members of the CMCB investigate both model and non-model organisms, bacteria and archaea, pathogens and non-pathogens.

In this thesis, I study the formation of large-scale structure and the physics of particle acceleration at large scales (~Mpc).

For each living organism health is ensured by correct functioning of its cells. Cells therefore have elaborate methods for regulation of their proteins.

Promotor: A. Kros

Promotor: W. Jaffe, Co-promotor: K. Meisenheimer

This thesis describes the Multi-site All-Sky CAmeRA (MASCARA), which consists of two small robotic telescope designed to detect exoplanets around the brightest stars in the sky.

Nature publishes an article on a paradoxical discovery in superconductivity. Physicists are searching for superconductivity at high temperatures so that less cooling is needed in for example MRI machines. News & Views article by Prof. Jan Zaanen in the same issue of August 19th.

Many important topics in computer science, such as the correctness of software, the efficiency of algorithms and the modeling of complicated systems, depend on sound theoretical underpinnings. In the Theory group, we study these fundamental building blocks and develop verification methods to prove system…

The first book ever on information-theoretically secure multiparty computation

This thesis is about cosmological inflation and its relation to observations.

Because thin systems can deform along the thickness with relative ease, the interplay between surface mechanics and geometry plays a fundamental role in sculpting their three-dimensional shape.

Promotor: Huub de Groot, Co-promotor: Francesco Buda

Promotor: A. Achúcarro, Co-Promotor: G.A. Palma

Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp

This thesis contributes to studying primordial cosmology theories and their detectability in future observations.

Many important and extraordinary discoveries have been made in Leiden. Roam the city and discover the fascinating stories behind them. All you need is your smartphone!

The Nobel Prize in Physics 2016 goes to David Thouless, Michael Kosterlitz and Duncan Haldane for theoretical discoveries in the field of topological materials. Haldane spent part of 2008 in Leiden; he is the 14th Lorentz Professor to win a Nobel Prize.

Lecture

Supervisor: Andrea Martella

Research into the wishes and (care) needs of older migrants

The Leiden University Sustainability Network is the platform for Leiden University staff and students to combine their efforts and support each other in making our university more sustainable.

Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.

Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)

In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.

Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar-Jagalska

Fitness is more than physical health alone. An equally important aspect of our general well-being is mental fitness. Mental fitness refers to the fitness of the mind. During your PhD research, there might be periods in which you feel insecure or down. It is essential to take good care of yourself. Don’t…

What should you do in an emergency?

Promotores: G.A. Persoon, H.H. de Iongh

Source: PLoS ONE, Volume 10, Issue 3 (2015)

In een goedgevuld Teldersauditorium vond op maandag 24 juni het symposium ‘Het Erfgoed van Meijers: 70 jaar waardering en inspiratie’ plaats. Vanuit verschillende perspectieven werd gereflecteerd op de omvangrijke nalatenschap van de Leidse hoogleraar Eduard Maurits Meijers, die precies zeventig jaar…

Five researchers from Leiden University have been awarded a Starting Grant by the European Research Council (ERC). This grant of on average 1.5m euros enables researchers who show potential to start their own project, lead a research team and implement their best ideas.

Physics professor Jan Aarts starts a collaboration with chip manufacturer Intel to perform fundamental research in low-power, cryogenic computing.

The Royal Holland Society of Sciences and Humanities (KHMW) has elected six professors from Leiden as members.

This thesis investigates the processing of words written in Japanese kanji and Chinese hànzì, i.e. logographic scripts.

Consumers are encouraged to think of food production and consumption as amoral activities – Michiel Korthals in his book Goed Eten: Filosofie van voeding en landbouw (2019, 353)