10,000 search results for “Research” in the Public website
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Contact
Do you have any questions about the master’s specialisation programme Research in Physics, Quantum Matter and Optics? Please contact us.
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Contact
Do you have any questions about the master’s programme Research in Biological- and Soft-Matter Physics? Please contact us.
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Contact
Do you have any questions about the master’s programme Research in Physics: Classical/Quantum Information? Please contact us.
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Una Europa
Our university is part of Una Europa: an alliance of 11 leading European research universities.
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Master Track Public Administration: Economics and Governance
Courses in English.
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Exploring the mechanism of targeted nanoparticle-mediated drug delivery using the zebrafish model
Exploring the mechanism of targeted nanoparticle-mediated drug delivery using the zebrafish model
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Naturalis Biodiversity Center
Naturalis Biodiversity Center is a national museum of natural history and a research center on biodiversity in Leiden, Netherlands.
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Study of utilization of combined hormonal contraceptives in Europe
Combined hormonal contraceptives (CHC) are associated with an increased risk of venous thromboembolism (VTE). In 2013, a review was published by the European Medicines Agency (EMA). In this review, the authors concluded that the risk of VTE varies by the type of progesterone in the CHC. Subsequently,…
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Single cell mechanics for disease biology and pharmacology
In this thesis, we describe the potential of cell mechanical phenotyping for immune cell characterization, diagnosis, drug testing, as well as treatment of disease.
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Microvasculature in Microfluidics: matching complexity with compatibility
In vitro disease models play a fundamental role in drug research. They enable the systemic identification and validation of disease mechanisms and the discovery of possible drug targets. However, more than often, drug candidates that are identified in vitro fail in the later clinical stages of drug…
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Events
Within the Mathematical Institute, the Algebra, Geometry and Number Theory research group organises several meetings.
- Studying at Leiden University
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Reasoning through Art
Inaugural lecture, delivered upon acceptance of the Chair in Theory of Research in the Arts, at the Faculty of Humanities, Leiden University, on 10 February 2017, by Professor H.A. (Henk) Borgdorff.
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Contact
Please feel free to ask any questions you may have about education or research at the Living Lab. You can contact the secretariat of the Institute of Environmental Sciences (CML).
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Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474, SCIENCE, 2017
The drug BIA 10-2474 inhibits fatty acid amide hydrolase (FAAH), a lipase that degrades a specific endocannabinoid. On the basis of this activity, BIA 10-2474 was being developed as a potential treatment for anxiety and pain. In a phase 1 trial of the drug, one subject died, and four others suffered…
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Trinidad, Tobago and the Lower Orinoco interaction sphere
An archaeological/ethnohistorical study.
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Louwerse, The 2017 Netherlands election
Political scientist Tom Louwerse (Leiden University), analysing several recent opinion polls, expects that after the March 2017 elections in the Netherlands, a relatively large number of mid-sized parties will gain representation in the Dutch parliament. If the predictions are anything close to the…
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Reduced stratum corneum lipid chain length relates to an impaired skin barrier function in patients with atopic dermatitis
Source: British Journal of Dermatology, Volume 170, Number 6, pp. E18-E19 (2014) ISBN:0007-0963
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The link between hearing loss, language, and social functioning in childhood
The aim of this thesis was to study the link between hearing loss, language skills, and social functioning in deaf and hard of hearing (DHH) children. Sufficient language skills are an essential prerequisite to develop appropriate communication skills, in order to join in conversations with others.…
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Rosema & Louwerse, ‘Response scales in Voting Advice Applications’
Voting Advice Applications represent popular election campaign tools in many countries, enabling voters to discover which party or candidate provides the best match with their political preferences. Political scientists Martin Rosema (University of Twente) and Tom Louwerse (Leiden University) examine…
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Microfluidics for high-throughput liposome formulation for personalized cancer vaccination
Liposomes hold great promise for peptide-based personalized cancer vaccination, especially when administered intradermally. However, current liposome preparation methods are very time consuming (resulting in long development times per formulation), whereas personalized cancer vaccination requires very…
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Join ENPAIR
Both researchers and evidence based practitioners can join ENPAIR. Joining the network requires no membership fees.
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Next Generation ImmunoDermatology project
The objective of the Next Generation ImmunoDermatology project (funding NWO, program NWA-ORC) is to deep profile the immune-mediated inflammatory diseases: i) atopic dermatitis (AD), ii) cutaneous lupus erythematosus (CLE) iii) chronic spontaneous urticaria (CSU) iv) hidradenitis suppurativa (HS) v)…
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Lipid chain length reduction correlates with the skin barrier function in atopic eczema patients and inflammation plays a role in the altered
Source: Journal of Investigative Dermatology, Volume 135, pp. S59-S59 (2015)
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The role of lipids in the barrier function of the skin
The outermost layer of the skin, the stratum corneum (SC), is responsible for the skin barrier function, protecting the body from pathogens, chemicals and other unwanted substances from the external environment. The SC lipid matrix provides the only continuous pathway through the SC and is considered…
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Development of an intradermal tuberculosis vaccine by combining dissolvable microneedle arrays and Mycobacterium tuberculosis antigen-containing
Mycobacterium tuberculosis (Mtb), the pathogen causing tuberculosis (TB), is the leader among all pathogens responsible for the most human deaths today and it is considered as one of the top 10 causes of death worldwide. There is an increasing occurrence of multidrug-resistant and even totally drug-resistant…
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Patient Remote Monitoring in Chronic Inflammatory Skin Diseases
Chronic inflammatory skin diseases such as psoriasis and atopic dermatitis affect both the physical and psychological well-being of millions of patients, leading to persistent symptoms like itchiness and sleeplessness. These conditions often result in decreased productivity and quality of life overall,…
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3D Image to Characterize and Optimize antibody-mediated antitumor immunity
Bispecific antibodies with one Fab arm binding to effector cells, such as T-cells and NK-cells, while the other Fab arm recognizing a tumor associated antigen (TAA) can be used to redirect these effector cells for tumor specific killing. Using bispecific antibodies to treat hematological cancers is…
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Development of an effective, safe, and painless intradermal tuberculosis vaccine based on microneedles loaded with antigen-containing nanoparticles
Tuberculosis (TB) is a major global health problem caused by the bacterium Mycobacterium tuberculosis (Mtb). In 2015, there were estimated to be 10.4 million new cases and 1.8 million deaths ascribed to TB, making it one of the top 10 causes of death worldwide. Unfortunately, the only current registered…
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Legal Implications of Airport Privatization in India
On Thursday 24 November 2016 Moses George will defend his PhD dissertation ‘Legal Implications of Airport Privatization in India’. The defence will commence at 11.15 hrs, in the Academy Building of Leiden University. The Supervisors are Professor Pablo Mendes De Leon and Professor Brian F. Havel (DePaul…
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The Cinematic Santri : Youth Culture, Tradition and Technology in Muslim Indonesia
The Cinematic Santri explores the rise and course over the last ten years of cinematic practices among a younger generation of NU associates (Nahdlatul Ulama), the largest traditionalist Muslim group in Indonesia and elsewhere.
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Novel Activity-Based Probes for Broad-Spectrum Profiling of Retaining β-Exoglucosidases In Situ and In Vivo
A high-end label: Cyclophellitol aziridine-type activity-based probes allow for ultra-sensitive visualization of mammalian β-glucosidases (GBA1, GBA2, GBA3, and LPH) as well as several non-mammalian β-glucosidases (see picture). These probes offer new ways to study β-exoglucosidases, and configurational…
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Impact-Insertion Applicator Improves Reliability of Skin Penetration by Solid Microneedle Arrays
Source: The AAPS journal, Volume 16, Issue 4, pp. 681-684 (2014)
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Safety First
You can find more information on the Dutch webpage. Click on the “Nederlands” button above.
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Phenoconversion
Pharmacogenetics is nowadays increasingly incorporated in the clinic to better predict pharmacokinetics and optimize dosing regimens of drug treatments. While this approach has been successful and improved our prediction of drug metabolism, drug levels within patients may still commonly deviate between…
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Central role of Claudin-1 in lesional but not in non-lesional atopic dermatitis
Source: Journal of Investigative Dermatology, Volume 134, pp. S44-S44 (2014) ISBN: 0022-202X
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Personalised pharmacotherapy in paediatric epilepsy : the path to rational drug and dose selection
The path to rational drug and dose selection
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Van der Meer, Janssen & Louwerse, ‘The predictive value of polls in a fragmented multi-party system’
Political scientists Tom van der Meer, Lisa Janssen (University of Amsterdam) and Tom Louwerse (Leiden University) analyse polls presented by the main polling agencies in the Netherlands, as well as micro-level panel data. They reach three main conclusions. First, vote intention polls in the Netherlands…
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Design of dissolvable microneedles for intradermal TB vaccination
Tuberculosis is an infectious disease which is spreaded through the air. It is caused by Mycobacterium tuberculosis and it led 1.7 million people to death in 2016. This mortarlity rate is concentrated in developing countries such as Indonesia, Philippines, Pakistan, and South Africa. These numbers make…
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Triple Bioorthogonal Ligation Strategy for Simultaneous Labeling of Multiple Enzymatic Activities
Three at the same time: a ligation strategy combining tetrazine–norbornene cycloaddition, Staudinger–Bertozzi ligation, and copper(I)-catalyzed click reaction was used to label the three catalytic activities of the proteasome simultaneously in a single experiment. The orthogonality of the three ligation…
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International Institute for Asian Studies
IIAS promotes critical, humanistic, and collaborative work on, with, in, and beyond Asia.
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Online Course Terrorism & Counterterrorism: Comparing Theory & Practice
This six-weeks online course delves into the research behind terrorism as it unpacks the assumptions and impacts of both terrorism and counterterrorism.
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Kennisbank
You can find more information on the Dutch webpage. Click on the “Nederlands” button above.
- Stem Cell Technology for Microphysiological Modeling
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Contact
Interested in our research or looking to collaborate? Get in touch with the Hominin FoodWays team!
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Team
We are a multidisciplinary team of researchers from Leiden University. Our work focuses on past diets, food processing, and human–environment interactions.
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Rachel de Jong -
Dual PhD Centre
Combining a job with a PhD Dual PhD programme
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Meer menselijke zorg met minder mensen?
Inaugural lecture
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Impact and Relevance
Below are some examples of ACPA projects that have a meaningful impact on arts and society. This page will be refreshed every now and then, presenting projects that exhibit how artistic research can significantly contribute to the way we perceive, understand, and relate to the world and to other pe…
