Which immune mechanisms are involved in host defense against Staphylococcal infection?

In this article, Lydie Cabane, Assistant Professor at the Institute of Security and Global Affairs, and Martin Lodge address the question of how to manage banking crises, a question that has gained prominence since the banking crisis of 2007-2009. This article sets out the rationale for regulating for…

PhD defence

PhD defence

The "Van Marum Colloquia" are a collaborative lecture series between the LION and LIC institutes, focusing on fundamental and applied surface science.

Researchers from Leiden University, the Netherlands, designed a novel metamaterial that buckles on demand. Small structural variations in the material single out regions that buckle selectively under external stress, whereas other regions remain unchanged. The research is published in this week’s Early…

Promotor: E. Bouwman, Co-promotor: S. Bonnet

There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.

The group is involved in training in areas of diagnostic skills, treatment/prevention/intervention, neuropsychological assessment, behavioral observations, clinical interviewing, knowledge of intellectual disability, autism, ADHD, psychosis and aggression.

The focus of the dissertation

Promotor: Roeland M.H. Merks

How does the development of digital technologies impact society, and law/regulation within that society?

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

Sevil Cakir-Kilincoglu defended her thesis on 18 December 2019

The research of the unit is aimed at the development of models to explain and describe the influences in social systems. Social influences are studied in three ways: from the perspective of group dynamics, from an individual-cognitive perspective, and from an economic and consumer psychological pers…

In this thesis we have discussed several parameters that affect the electrochemical conversion of enviromentaly harmful molecules such as nitrates and carbon dioxide to more valuable and less deleterious compounds, in order to cast light onto the mechanism of the reaction to achieve an efficient and…

Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.

What is the role of emotion regulation in coping with interpersonal feedback?

Do humans and zebra finches share cognitive mechanisms that are important for speech perception?

This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: Prof. dr. V. Vitelli

Promotores: Prof.dr. B.R. Katzy, Prof.dr. K. Sailer (Munich University)

Because thin systems can deform along the thickness with relative ease, the interplay between surface mechanics and geometry plays a fundamental role in sculpting their three-dimensional shape.

The research presented in this thesis explores the chemotherapeutic potential of metal-based compounds as chemotherapy agents, with an initial focus on the synthesis and DNA interaction studies of platinum and palladium compounds utilizing the [Pt(bapbpy)]2+ scaffold. The study identifies intercalation…

‘Schiedsgerichte in den Aussenverträgen der EU. Neue Entwicklungen unter Einbezug der institutionellen Verhandlungen Schweiz–EU’, Jusletter 28 May 2018

Promotor: Prof.dr. T. Schmidt

In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.

Research groups in the Biological & Soft Matter Programme unravel mechanisms in biological processes and develop novel bio-inspired soft materials.

What are the mechanisms involved in the reconciliation of value conflicts and which interventions are capable of resolving such disputes?

The research aims to explore the evolutionary adaptability of enzymes and the impact of temperature on protein evolution pathways, using M. tuberculosis β-lactamase BlaC as the object of study. Enzymes inherently embody a delicate balance between activity and stability, and the acquisition of new enzymatic…

Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.

National and international actors have attempted to provide accountability for the events at Srebrenica in July 1995. This research project aims to draw lessons learned from those multiple efforts in assessing whether securing a measure of ‘justice’ for the victims has been successful and how national…

The research programme Industrial Ecology aims to support the ecological transformation of society and environment towards sustainability. The research subject is Industrial Ecology in its broadest definition, covering environmental systems analysis, and incorporating the social and economic aspects…

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.

Gibbs measures, as used in Statistical Mechanics, have a definition that is remarkably similar to the definition ofg-measures, used in dynamical systems.

Promotor: V. Vitelli, Co-promotor: J. Paulose

Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn

Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…

Lecture, Tuesday Talks: Science Insights

This weeks marks the 10th anniversary of the European Research Council. For the past decade, the council has contributed to many scientific projects all over Europe, including Leiden University. It has funded almost 7,000 researchers, leading to just short of 100,000 scientific articles. A total of…

Three major research projects involving Leiden scientists have been awarded a grant from NWO’s Gravitation Programme. The projects are on innovation processes, organs-on-chips and quantum software.

Physics and Engineering Approaches to Biomedicine and Pharmacology

A major challenge in the formulation of biopharmaceuticals is to overcome their inherent instability during production, storage, transportation, handling and administration. We are studying underlying mechanisms of degradation of biopharmaceuticals (including therapeutic proteins, vaccines and advanced…

Exactly 138 years ago, Albert Einstein came into this world to forever change our understanding of it. The Leiden physics institute, where he frequently worked, organised a symposium in honor of his birthday.

From publishing students, to addressing bottlenecks in education logistics and a completely new bachelor’s programme. Scroll through our highlights on educational innovation and achievements of our outstanding students.

PhD defence

PhD defence

PhD defence

PhD defence