1,793 search results for “molecular biology” in the Public website
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Leiden scientists map cell types in fetal kidney
Kidney failure is a serious issue because kidneys cannot regenerate themselves after injury. A possible solution consists of artificially growing healthy kidney tissue. To achieve that, scientists first need to understand kidney development during the earliest stages, in the fetus. Leiden researchers…
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AI model accurately predicts endometrial cancer recurrence
Researchers from the Leiden University Medical Center (LUMC) have developed an AI model that accurately predicts the risk of endometrial cancer recurrence.
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Astronomy at Dutch universities is worldleading
Astronomy departments at Dutch universities is among the top of the world rankings for astronomical institutions. This is the conclusion drawn from a recent evaluation of the Netherlands Research School for Astronomy (NOVA) and the astronomy institutions of the University of Amsterdam, the University…
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MRI Machine at the Nanoscale Breaks World Records
A new NMR microscope gives researchers an improved instrument to study fundamental physical processes. It also offers new possibilities for medical science, for example to better study proteins in Alzheimer patients’ brains. Publication in Physical Review Applied.
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Post-lockdown ceremonies: corona-proof but festive nonetheless
After the lockdown, it was again possible to receive graduates and guests at the University. In recent weeks, BSc and MSc graduates from various study programmes were festively awarded their diplomas in a special corona-proof setting in the restaurant of the Gorlaeus Lecture Halls building. This resulted…
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Observing a changing platinum electrode
The surface of platinum electrodes changes much more during use than was previously thought. In a collaboration between the Leiden Institutes of Chemistry and Physics, chemists Leon Jacobse, Yi-Fan Huang and Marc Koper, and physicist Marcel Rost have been able to show this for the first time. Publication…
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Aggressiveness of cancer cells halted
Zebrafish-human communication shows that cancer cells lacking a signaling protein are less able to develop aggressive metastatic properties. This discovery has been made by molecular cell biologist Claudia Tulotta. PhD defence 14 June.
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Different medication dosage for morbidly obese patients
PhD research recently completed by pharmacologist Margreke Brill shows that morbidly obese patients should be given a different dosage of the drugs Cefazolin and Midazolam. This could also apply to other drugs such as anti-cancer drugs as well as antibiotics and Margreke Brill is advocating a change…
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Beijing Normal University visits Leiden for Astronomy Summer School
The Leiden Observatory was very pleased to welcome eight bachelor’s students from Beijing Normal University at 8 July for the BNU Astronomy Summer School. In two weeks’ time, the Summer School students followed an interactive programme in computational astrophysics. ‘It’s surprising how much you can…
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Students take a look at the Bio Science Park Neighbours
Many students cycle past the companies of the Bio Science Park every day, but what actually happens behind those doors? And is there a future there for students after their graduation? The Bio Science Park Excursion answers these questions.
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New insights on graphene
Graphene floating on water does not repel water, as many researchers believe, but rather attracts it. This has been demonstrated by chemists Liubov Belyaeva and Pauline van Deursen and their supervisor Grégory F. Schneider. Publication in Advanced Materials.
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Seventeen million for Dutch X-omics Initiative
The Dutch X-omics Initiative has received seventeen million euros from NWO as part of the National Roadmap for Large-Scale Infrastructure. Leiden University’s metabolomics research led by Thomas Hankemeier is one of the participators.
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How a pathogenic bacterium searches for food
Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.
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New research centre for studying planet and star formation
The ALMA Local Expertise Group (Allegro) is located in the Leiden Observatory (Sterrewacht). Professor Ewine van Dishoeck: ‘The Netherlands has played an important role in establishing ALMA. Thanks to this subsidy, we can now reap the scientific benefits.'
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New professor of Biotherapeutics Delivery at LACDR
Matthias Barz has been appointed full Professor of Biotherapeutics Delivery at the Leiden Academic Centre for Drug Research (LACDR).
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Powerful new Leiden 'super antibiotic' may overcome resistance
The prestigious journal Science Translational Medicine has published a study by researchers from the Institute of Biology Leiden (IBL) on a potent new antibiotic that can overcome resistance. ‘The idea was to tweak the original antibiotic and create a next-generation drug’, says Nathaniel Martin, professor…
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Advancing helminth glycomics Structural specificity and mmunogenicity of schistosomal and filarial glycans
PhD defence
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Hall of Fame 2017
Many of our staff and students have won prizes over the past year. Others have been awarded a subsidy, or, because of their eminence in their field, they have been appointed members of academic societies or have taken up positions in the community. Reasons enough to be proud of them and to include them…
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The solution to antibiotic resistance might be under our feet
Biologist Nataliia Machushynets felt like she was ‘looking for a needle in a haystack’, trying to find new antibiotics to help solve the problem of resistance. During her PhD research, she did find what she was looking for, in the soil beneath our feet.
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Thirteen NWO Open Competition XS grants for Leiden researchers
From medicines from snake venom to supercrops and the origin of words. Thirteen researchers from Leiden University will receive Open Competition XS grants from the Dutch Research Council (NWO).
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LED3 & LUCID Drug Discovery Meeting
Conference
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Cucurachi, Behrens and Matthee are teacher, discoverer, and PhD candidate of 2018
Environmental scientists Stefano Cucurachi and Paul Behrens and astronomer Jorryt Matthee have received prizes during the New Year's reception of the Faculty of Science on Tuesday 8 January. In addition, Kavli Prize winner Ewine van Dishoeck announced a new award.
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Decomposing tears in order to detect Dry Eye Disease
By measuring proteins in tears, ophthalmologists can more easily diagnose dry eyes (Dry Eye Disease). Peter Raus, a Belgian ophthalmologist and PhD student at the Institute of Biology Leiden, developed a new method for protein determination in tear fluid. The technique is also promising for the early…
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Resolving the Dynamic Structure of Chlorosomes in Green Sulfur Bacteria by MAS NMR
PhD defence
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Parade of creative science communication products
From bedtime stories about mathematics to podcasts about microplastics and games on weeds: master students from the Science Communication & Society track presented the real-life products they developed during their final presentations on 20 December. Many of the products are already implemented by c…
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Gilles van Wezel steps down as SD of the IBL: Hubertus Irth appointed as temporary replacement
Gilles van Wezel will step down as Scientific Director (SD) of the Institute of Biology Leiden (IBL) as of June 17th. He has held this position since September 2018. Van Wezel will be temporarily succeeded by Hubertus Irth, the current SD of the Leiden Academic Centre for Drug Research (LACDR). Irth…
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Discoverer of the Year, Best Dissertation and Education prize 2015
During the Faculty of Science New Year's reception, Daniël Rozen was named Discoverer of the year 2015. Nienke van der Marel and Koen van der Maaden both won the prize for the best dissertation and Jeroen van Smeden was named Best Teacher of 2015.
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New Year's Reception
Conference
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Science Minor Information Market
Study information
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Artificial Intelligence at the Crossroads of Histopathology: A New Era in Endometrial Cancer Precision Diagnostics and Prognostics
PhD defence
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Microglial lipid metabolism: a delicate balance
PhD defence
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Fourteen women professors take over the Senate Chamber
Fourteen women professors are to be given a place in the classic portrait gallery in Leiden University’s Senate Chamber. The portraits will be unveiled on 8 March – International Women’s Day – by former Minister of Education, Culture and Science Jet Bussemaker and Rector Magnificus Carel Stolker.
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Unraveling the mysteries of Multiple Sclerosis
Leiden chemists discovered a new mechanism which might explain how multiple sclerosis shifts to a more severe form. Their findings contribute to unravelling the mysterious course of the disease. They have published their findings in the journal Biochemistry.
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Making everything we know computer-readable
Data and information should be stored in a way that computers can understand, says Barend Mons, professor of Biosemantics at the Leiden University Medical Center and Chair of the High Level Expert Group for the European Open Science Cloud. We speak with him about FAIR data, knowlets and nanopublicat…
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Vici grant for Jeroen Codée: ‘I want to understand how sugars are formed’
Although sugars are widely used in biological and medical research, their synthesis is still badly understood. Jeroen Codée has received a Vici grant of 1.5 million euros for systematically studying the production of sugars. ‘I want to genuinely understand the reactions.’
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How bittersweet sugar chemistry targets pathogens
The challenge is considerable, but so is the satisfaction when it succeeds: creating complex sugar molecules that play a role in biology.
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How our single-celled relatives package their DNA
A group of single-celled organisms organises its DNA in a similar way to higher organisms such as plants, animals, and fungi. However, the way packaged DNA is read out differs between the two related groups, Bram Henneman discovered. PhD defence on 5 December.
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Preparing for the next pandemic: scientists discover a new class of influenza antivirals
Researchers from Leiden University, University of York, University of Barcelona/IQTCUB/ICREA and The Francis Crick Institute report a new class of experimental compounds that powerfully block influenza viruses. The findings offer a potential new strategy for treating flu infections and preparing for…
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ERC Consolidator Grants for four Leiden researchers
The European Research Council has awarded ERC Consolidator Grants to four researchers from Leiden. These grants of up to 2m euros will enable them to continue and expand their research.
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What Darwin couldn’t see: Expedition to uncover invisible life in Galápagos
An international research team is to search for invisible life in the Galápagos Islands. The diversity of bacteria and other microscopic organisms may not be evident to the naked eye, but it is essential to nature. To the islands' giant daisies, for instance: unique endemic plants that are currently…
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Van Marum Colloquium: New frontiers in modeling nanoporous materials and their applications at the crossroads of quantum mechanics, statistical
Lecture
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ERC Starting Grants for five young Leiden researchers
Five researchers from Leiden University have been awarded a Starting Grant by the European Research Council (ERC). This grant of on average 1.5m euros enables researchers who show potential to start their own project, lead a research team and implement their best ideas.
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LED3 Lecture: Harnessing methylation: Chemical and metabolic tools for analyzing and regulating mRNA
Lecture
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Major European subsidy for membrane fusion
The European Research Council (ERC) has awarded chemist Dr Alexander Kros a Starting Independent Researcher Grant of 1.4 million euro. He will be using the grant to study how molecules penetrate the natural barrier of a cell membrane. If his research is successful, it will in time bring about a revolution…
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Better ligands for G Protein-Coupled Receptors
The receptor nomenclature committee of IUPHAR, the International Union of Pharmacology, has several subgroups. Among these are a few that our division is involved in, those for adenosine, nicotinic acid, and GnRH receptors.
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ICM 2018 project results
Within the ICM 2018 project, Leiden University cooperated with 25 partner universities from 14 countries. In total, 97 mobilities were granted to this project - 65 mobilities were realised (some mobilities had to be ended prematurely due to covid-19, others were finished online).
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Cognition in the digital environment laboratory
To develop a new generation of brain science (and train scientists) focused on explaining complex real-world behavioural patterns.
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‘Ultimately, the goal is to develop antibiotics for tuberculosis with a lower risk of resistance’
Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…
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In Memoriam Professor Huib Ovaa
On the 19th of May 2020, our dear colleague and friend Professor Dr. Huib Ovaa has passed away from prostate cancer. Last summer Huib became ill, and in first instance it appeared that he had attracted a relatively harmless infectious disease. Unfortunately, it became soon apparent that he suffered…
