David Versluis successfully simulated an infant gut virtually. This is crucial for research on improvements in formula milk. Currently, such research primarily relies on diaper contents, which is not optimal. Versluis defended his doctoral thesis on April 23.

Humans have influenced nature since as early as the Ice Age, and over the past century man’s impact has become even greater with our many new technologies and a growing world population. Leiden researchers study this impact and how we can keep it within reasonable limits so that nature can be preserved.…

On the 1st of October a new project funded by the Joint Industry Programme (JIP) started at the IBL on the potentially negative effects of sound on fish. Behavioural biologist and bioacoustic specialist Dr. Hans Slabbekoorn leads the international research team.

This academic year 49 promising international students will start their master’s degree here thanks to a Leiden University Excellence Scholarship (LExS). The students, all from outside the EU, were welcomed in a special ceremony on 5 September. Who are they?

How do you know if a drug will actually work? The Leiden-based spin-off Omivera is developing a new technology that could provide clearer answers. The young company received a seed investment from the investment fund UNIIQ to support its development.

What do you do when a discovery in the lab shows real promise? Scientist Mirjam Huizenga founded a startup to develop a new treatment for nerve pain caused by chemotherapy. ‘The goal is to give patients a better option.’

Remko Offringa, Associate Professor in Plant Developmental Genetics, and Associate Professor in Molecular Microbiology Arthur Ram both have been appointed as the new Directors of Education at the IBL. Offringa in the role as Director of Education for the Master program and Ram as Director for the Bachelor…

Streptomycetes are similar to moulds, but these bacteria live in the soil. They are very popular in biotechnology because they produce a great many antibiotics and enzymes. Gilles van Wezel will be using his Vici subsidy to study ways of increasing their production.

How do our cells keep DNA stored away? To find out, biochemist Remus Dame received a 3 million euro Science-Groot grant. Leiden University will share the grant with TU Delft, VU Amsterdam and the Hubrecht Institute.

Geneticist Hans Clevers will give the first Niko Tinbergen lecture new style on 10 December, which is all about stem cells. The young Leiden professors Ariane Briegel and Susana Chuva de Sousa Lopes talk about bacterial noses and the cultivation of egg cells in the lab in short introductory lectures…

Bringing your drug candidates to patients is what many academic chemists dream about, but the road to this goal is long and bumpy. Now, Leiden small molecule nizubaglustat is ready for phase 3 clinical trials. This is thanks to a €132 million funding secured by the biotech spin-out Azafaros.

Researcher Daan van der Vliet, together with colleagues from the Netherlands Institute for Neuroscience, Leiden University and Utrecht University, has discovered an important mechanism that may be linked to severe cases of multiple sclerosis (MS): the brain contains large numbers of abnormal immune…

Four of Leiden's top researchers have been awarded substantial grants by the European Research Council.

The Dick Stufkens Prijs for the best PhD thesis of the Holland Research School of Molecular Chemistry (HRSMC) has been awarded to Dr Tatu S. Kumpulainen for his thesis “Proton-Transfer Reactions in ‘Super’ Photoacids and Supramolecular Assemblies”. It describes his innovative research into methods for…

The Dick Stufkens Prijs 2010 is awarded to Dr. Niels Elders. The prize is given by the Holland Research School of Molecular Chemistry for his Ph.D. thesis “Multicomponent Approaches to Molecular Diversity & Complexity”, in which he describes the development of various new multi-component synthetic procedures…

The Dick Stufkens Prize 2018 for the best PhD thesis of the Holland Research School of Molecular Chemistry (HRSMC) will be awarded to Dr Stefan Vuckovic. In his thesis, Vuckovic presents a new and innovative approach to the quantum mechanical calculation of atomic and molecular energies. It lays the…

A full overview of BPOC/SSNMR PhD theses.

PhD defence

The Royal Netherlands Academy of Sciences (KNAW) has awarded an Academy Professorship to Ewine van Dishoeck, Professor of Molecular Astrophysics at Leiden University.

A team of laboratory astrophysicists from Leiden University managed to make glycerol under conditions comparable to those in dark interstellar clouds. They allowed carbon monoxide ice to react with hydrogen atoms at minus 250 degrees Celsius. The researchers publish their findings in the Astrophysical…

On 28 February, Professor E.W. Meijer, member of Leiden University’s Board of Governors, was appointed Commander in the Order of the Dutch Lion.

Emeritus Professor of Molecular Astrophysics Ewine van Dishoeck has been named a Citation Laureate by Clarivate, a research analytics provider. Clarivate considers her an influential researcher of the calibre to win a Nobel Prize.

Surface Reaction Barriometry: Methane Dissociation on Flat and Stepped Transition-Metal Surfaces.

Chemical biologists from Leiden, led by Dr Mario van der Stelt, have discovered substances that can reduce inflammation processes in the brain. This is a first step in the development of potential medicines for the treatment of brain diseases like Alzheimer's and Parkinson's. Published in Proceedings…

Gilles van Wezel of the Institute of Biology Leiden will lead a European consortium to search for new medicines and disease-suppressive microbes while preserving biodiversity. The consortium will explore the largely unknown potential of marine microorganisms.

Core Facilities are shared resources that provide access to instruments, technologies and services to researchers across the Institute of Biology.

Mapping of bacterial genomes to combat infectious diseases

An international team led by Leiden astronomers has discovered diverse ices in the darkest, coldest regions of a molecular cloud. To do so, they used the James Webb Space Telescope. This discovery allows astronomers to examine the simple icy molecules that will be incorporated into future exoplanets,…

Marileen Dogterom, Professor bionanoscience in Delft and Professor molecular physics in Leiden, will take a seat at the KNAW board as of June 1st. She is appointed for four years, one day per week. Dogterom succeeds Nobel Prize winner Ben Feringa, who completed his term.

Professor Bert Meijer has been appointed to the Board of Governors of Leiden University by Minister of Education, Culture and Science Jet Bussemaker for a term of four years from 1 January 2017.

On 1 March, Lennart Schada von Borzyskowski will start on a tenure track position at the Institute of Biology Leiden (IBL). With a focus on the natural and synthetic biochemistry of environmental bacteria, he wants to apply their features to health and sustainability issues.

From 22 to 24 October, researchers of the MARBLES-project informed museum visitors about microbes: bacteria and fungi that live all around us. The event was organised around the Micro-day of Leiden, which is this year’s EU City of Science.

Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.

A bacterium hiding from the immune system and picking up bits of DNA from its environment. The result: gaining new traits, such as better protection against antibiotics. Fortunately, we have not found such a damning scenario yet. However, PhD student Renée Kapteijn did find the first clues, which…

Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…

BRAIN Biotech and the Leiden University will jointly develop an Aspergillus based production strain with high yield and thus contribute to a bio-based circular economy. The cooperation is based on BRAIN´s molecular tool BEC.

PhD defence

PhD defence

The Dick Stufkens Prize 2021 for the best PhD thesis of the Holland Research School of Molecular Chemistry (HRSMC) has been awarded to Klaas van Leest for his thesis 'Open- Shell Cobalt Complexes with Redox-Active Ligands; Electronic Structure and Nitrene Transfer Reactivity'. Van Leest, who is now…

The Royal Netherlands Academy of Arts and Sciences (KNAW) selects prominent researchers as members based on their scientific achievements. On September 17th, the KNAW will install 21 new members, including Leiden physicist Michel Orrit and chemist Hermen Overkleeft.

Researchers led by Professor of Chemistry Marcellus Ubbink have recently published a study in Proceedings of the National Academy of Sciences (PNAS) about the dynamics of an important redox enzyme. This work was accomplished thanks to an NWO VICI subsidy granted to Professor Ubbink.

Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…

Sustainable rose smell that can be produced on a large scale. Tobias Fecker made this into a possibility during his master's thesis, which was a collaboration between the IBL and the TU Delft. He wins the fourth edition of the Krijn Rietveld Memorial Innovation Award.

Plant scientist Omid Karami is the first winner of the Krijn Rietveld Memorial Innovation Award. The jury praises the outstanding quality of his scientific research as well as the positive societal impact and commercial potential of his work.

Bacteria found in soil specialise in the colony by division of labour. Some of the bacteria produce antibiotics, even when it comes at the expense of their individual reproduction success, to defend their colony against competitors. Publication in Science Advances.

The Fritz Zwicky Prize 2022 for Astrophysics & Cosmology has been awarded to Prof. Ewine F. van Dishoeck for her pioneering, decades-long work in astrochemistry and molecular spectroscopy, as well as for her leadership within the astronomical community. The award was announced today by the European…

Endocannabinoids - the body's own marijuana - are promising departure points for drug research. Professor of Molecular Physiology Mario van der Stelt examines whether inhibiting their production can be a way to fight inflammatory brain disease and to combat obesity. Inaugural lecture 19 October.

Fijs van Leeuwen, Professor of Radiology, Molecular Imaging and Image-Guided Therapy, advocates an open and respectful academic culture that always puts the patient first. He delivered his inaugural lecture on 13 November.

Leiden chemists Marc Koper and Ian McCrum have discovered that the degree to which a metal binds to the oxygen atom of water is decisive for how well the chemical conversion of water to molecular hydrogen takes place. This insight helps to develop better catalysts for the production of sustainable hydrogen,…