This thesis investigates the syntax of object marking in Sambaa and the Bantu languages in general, with particular focus on Swahili and Haya, as points of comparison.

This dissertation focuses on the overt marking of φ features encoded on perfective active auxiliaries in a group of Southern Italian dialects.

In this thesis,

The Role and Effectiveness of the G20. In this article, published in The Changing Global Order part of the United Nations University Series on Regionalism book series, author Jaroslaw Kantorowicz discusses the evolution of the G20.

To meet the rising demand for minerals driven by the global shift to clean energy technologies, ensuring responsible and resilient supply chains is critical. Minerals like cobalt, lithium, and nickel for batteries, neodymium and zinc for wind turbines, and indium for solar panels are essential.

Promotor: G.R. de Snoo

Promotor: W. Jiskoot, Co-promotor: H.A. Every

Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.

This article examines the consequences of stereotypical beliefs regarding gender, traits, and leadership styles for manager preferences.

Behavioral and neural mechanisms underlying risky decision-making in adolescents

How to facilitate the translation of science into innovation

This paper investigates possible convergence of issue salience of terrorism among citizens within the European Union for ten jihadist attacks in the period 2015–2017 using Eurobarometer survey data.

This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

Polymyxins are clinically used antibiotics, discovered in mid-20th century. Once abandoned due to excessive nephrotoxicity, they are now used increasingly to address infections caused by multi-drug resistant Gram-negative bacteria.In this thesis, we describe the development and synthesis of analogues…

Promotores: Prof.dr. A.G.G.M. Tielens & Prof.dr. L. Kaper (UvA)

Promotor: P. T. de Zeeuw, Co-promotor: N. Neumayer; G. van de Ven

Gibbs measures, as used in Statistical Mechanics, have a definition that is remarkably similar to the definition ofg-measures, used in dynamical systems.

Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

In the research programme Microbial Sciences we perform state-of-the-art research in the field of biotechnology and microbial sciences.

Wout Broekema highlights how organisations not only learn from crises but also forget, losing crucial knowledge and practices over time.

What drives public agencies’ propensity to engage in more extensive practices and/or to initiate more far-reaching mechanisms of accountability than those mandated by law? In other words, what are the drivers of voluntary accountability?

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

This article studies the influence of framing on preferences for cooperation with the EU.

In which way and to which extent is integration articulated in concept maps and which factors affect the resulting concept maps? By which factors is the perceived usefulness of such concept maps affected?

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

The Violence and Violence Prevention research group at Leiden University focuses on understanding and preventing violence in modern societies. The group offers two key educational programmes: the Minor Violence Studies and the Governance of Violence specialisation within the Master’s in Crisis and Security…

Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…

The debate in Europe about digital sovereignty, technological sovereignty, data sovereignty and strategic autonomy has been building over recent years at both the EU level and the level of individual Member States. The different concepts – and their diverse interpretations – cover the sovereignty concerns…

Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.

Promotores: Prof.dr. E.A.L. Biessen, Prof.dr. T.J.C. van Berkel

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

Understanding individual differences in self-regulation in boys with ODD/CD on the level of brain, cognition and behavior

This article examines how the threat of terrorism has been addressed at the policy level through an analysis of a specific case in Mali.

Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa

Curved single crystals provide variable, but well-defined surface structures.

This thesis investigates a pharmacological challenge model induced by Toll-like receptor 7 (TLR7) activation, focusing on skin inflammation and its implications for early drug development.

This thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular…

The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).

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Transcutaneous vagus nerve stimulation (tVNS) was tested in chronic worriers. tVNS may reduce spontaneously occurring negative thought intrusions. After a worry induction, there was no longer an effect of tVNS. tVNS did not affect physiological responding to worrying.

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

Intergenerational transmission refers to the complex and dynamic process with which values, ideas and behaviors are transmitted across generations. We are specifically interested in the intergenerational transmission of behaviors and beliefs that might result in harm to the individuals involved or society…

Kantorowicz & Voigt examine whether federal systems, with their multiple levels of government, lead to higher constitutional compliance

Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…

Lipid formulations have demonstrated strong potential for nucleic acid delivery,particularly with the success of COVID-19 vaccines. Despite these advances, manyaspects of lipid formulations remain unclear.

We investigate emergent structures and dynamics of soft materials self-assembled from microscopic constituents.

Wetland plants are distinguished from plants of other terrestrial ecosystems by their adaptations to specific habitat stresses, including waterlogged and flooding and the subsequent abundance of phytotoxic compounds.