Dutch researchers are joining forces to conduct research together with a series of societal partners to keep the biological clock healthy in our modern 24-hour society. The BioClock consortium will receive a research grant of no less than 9.7 million euros for this. It is one of the projects that receive…

Soil bacteria can produce a wealth of antibiotics that are new to us, claims Gilles van Wezel, Professor of Molecular Biotechnology at the Institute of Biology Leiden. His research group has developed a method that can rapidly identify and produce these unknown compounds.

A group of biology students are working on a solution to the world’s plastics problem by getting bacteria to make biodegradable plastic.

The Faculty of Science forges new research collaborations with the Institut Teknologi Bandung in Indonesia in the fields of tropical diseases, e.g. tuberculosis and medical biotechnology.

The number of lions in Kenya is decreasing alarmingly, due partly to the encroaching cities and the development of the countryside. Together with local scientists and inhabitants, Leiden biologists are studying how this decline can be halted. ‘Lions are cleverer than we thought.’

Bacteria that fluoresce green, blue or red may play a role in combatting resistance against antibiotics. Under the motto of 'Say yes to stress', thirteen ambitious Leiden students are aiming to amass 9,000 euros to carry out their research project.

At Leiden Observatory, researchers investigate the origin of stars and their planetary systems. They detect and characterize planets around other stars, which are called exo-planets. They study how stars and planets form. And they follow molecules from interstellar clouds to nascent planet systems.…

The Skin Barrier and Vaccination group is led by Prof. Joke Bouwstra. One of the key functions of the skin is its barrier function, which is located in the uppermost layer of the skin, the stratum corneum. The stratum corneum consists of enucleated dead cells (corneocytes) embedded in a lipid matrix.…

Supervisor: Maarten Doornbos

How do plant defense genes get activated?

The Human Origins group at Leiden University studies the archaeology of hunter-gatherers, from the earliest stone tools in East Africa, more than three million years old, to the origin of sedentary societies towards the end of the last ice age.

Are you looking for a research project?

Which plant leaf characteristics are involved in thrips resistance in tomato?

Research at the MCBIM group is comprised of the following research themes:

From molecule, to cell, to organism. The high-level drug research at the Cell Observatory aimes at reducing the spread of cancer and developing new medicines for tuberculosis.

Supervisor: Lizi Xia

About nine million people worldwide contract tuberculosis each year. Research into new treatment for this disease has received fresh stimulus with more efficient techniques and a new understanding of how the tuberculosis bacteria works.

The research of this PhD project can be subdivided into two main disease areas: migraine and stroke. For both we will be investigating how artificial intelligence (AI) and machine learning (ML) techniques can be used to study these afflictions, their (early) detection, and their potential treatment.

Researchers at LED3 are working together with biopharmaceutical company Galapagos to develop software for use in early drug discovery (funded by NWO). This software is able to design molecules with several simultaneously optimized characteristics and will also take prediction reliability into consideration…

Researchers at Leiden Observatory study the fundamental physics that creates structure in the Universe. These processes collect matter into galaxies and gas into stars. With the use of powerful telescopes and advanced calculations and computer simulations, Leiden astronomers seek to understand the origin,…

Since the early 1990s, one can isolate the optical signal of a single molecule and single-molecule spectroscopy has quickly grown into an important research field.

Supervisor: Gerard van Westen

In CCLS several subgroups have formed, below you can find an overview of these groups with the names of the leading researchers and a short outline of the project.

The Biomedical Metabolomics Facility Leiden (BMFL) is the core metabolomics facility of Leiden University and the Metabolomics and Analytics Centre (MAC). We offer a highly structured environment for advanced MS-based metabolomics studies and build on fully validated, state-of-the-art assays that each…

Macromolecular Biochemistry is a section of the Leiden Institute of Chemistry at Leiden University, comprising the PIs Marcellus Ubbink, Remus Dame, Lars Jeuken, Anne Wentink, Sebastian Geibel, Anjali Pandit, René Olsthoorn, Alia, and Steffen Brünle.

Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…

This specialisation focuses on two important trends in health care: early diagnosis and developing the most targeted patient-specific treatment possible with the shortest possible recovery time and minimal side effects.

Decision support tool for cell therapy commercialization and business development

The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.

Within the two-year Astronomy master’s programme, you can choose from seven specialisations, ranging from fundamental or applied astronomy research in cosmology, instrumentation or data science, to combinations of astronomy research with education, management or science communication.

When you apply for admission, you’ll be asked to submit several documents.

When you apply for admission, you’ll be asked to submit several documents.

Are you curious about how science and technology contribute to a sustainable and innovative future? At Leiden University, you’ll explore the world of data, natural laws and living systems. From mathematics to artificial intelligence, from climate challenges to high-tech innovation: you’ll learn to analyse…

Are you curious about how science and technology contribute to a sustainable and innovative future? At Leiden University, you’ll explore the world of data, natural laws and living systems. From mathematics to artificial intelligence, from climate challenges to high-tech innovation: you’ll learn to analyse…

Whether a microbe is beneficial or harmful to a plant can now be predicted with high accuracy thanks to bacLIFE. This bioinformatic tool with an intuitive interface makes it much easier to unlock the secrets of bacterial genomes. A group of Leiden biologists presented it in Nature Communications.

Scientists have discovered that starlings and parrots can imitate the complex sounds of Star Wars droid R2-D2 remarkably well. Their study reveals how the structure of a bird’s vocal organ determines its vocal abilities – and how citizen science helps uncover it.

Primate and test specialist Jane Goodall paid a visit to the Hortus botanicus in Leiden on 21 May for a ‘meet & greet’. Goodall, a world-famous researcher and nature protectionist, was presented with an orchid named after her and used the occasion to draw attention to the issue of plant protection.…

Thread-like bacteria make cells that no longer have a cell wall under the influence of osmotic stress. A remarkable discovery, since the cell wall serves as a protection barrier for bacteria. It could also help to explain how pathogenic bacteria can hide in our body from our immune system. A team of…

Finding structure in disordered proteins and developing drugs for undruggable diseases: it might sound like mission impossible, but pharmacologist Alireza Mashaghi and his team are right on top of it. Their project was awarded by NWO through the Open Competition Domain Science -XS, a competition that…

An interdisciplinary team of Leiden researchers has discovered that wasting syndrome, a severe byproduct of tuberculosis, is the same for all humans and animals studied. The discovery offers new opportunities to investigate the still insufficiently understood condition. The scientists also developed…

Of the 111 Spinoza Prizes that have been awarded since 1995, 28 have gone to researchers from Leiden University.

She narrowly defied bureaucracy and spent days angling for cod. In the North Sea, marine biologist Inge van der Knaap discovered that noise significantly disturbs fish behaviour. ‘There is now a lot of attention for underwater noise.’

Current antibiotics only address very few target proteins in bacteria to kill them. Researchers know that there are more possible target proteins to tackle the bacteria. The question is: which ones. Thanks to the NWO Vidi Grant, Assistant Professor Molecular Physiology Stephan Hacker and his team can…

The discovery in 2001 of the importance of microRNAs turned the world of molecular biology upside down. The small particles of RNA also attracted the attention of university lecturer Erno Vreugdenhil. Vreugdenhil: ‘Within five to ten years the first microRNA-directed medicines will come onto the mar…

Having a bachelor's, a master's and a PhD in Chemistry, Elena Sánchez López shifted to a more biological field of research for her postdoc. She completed all her studies at the University of Alcala, in Spain, before applying for a LEaDing fellowship at Leiden University, a Marie Sklodowska-Curie Cofund…

In an Advance Online Publication biophysicist John van Noort and others show using magnetic tweezers that DNA is folded in compliant helices of chromatin. This allows enzymes access to the DNA needed for gene expression. Van Noort's research group made the discovery in close partnership with researchers…