This thesis investigates the syntax of object marking in Sambaa and the Bantu languages in general, with particular focus on Swahili and Haya, as points of comparison.

Promotor: Prof.dr. M.K. Richardson, Co-Promotor: F. Witte

A major goal of ABS research is to overcome one of the major bottle-necks in metabolomic research: the lack of a high-throughput infrastructure in which thousands of samples can be processed in a standardized and cost-effective way (max. a few tens of Euro’s per sample for a full metabolome profile).…

The investigations described in this thesis lay out strategies aimed at advancing antibiotic research and development. The examples presented revolve around two main approaches: understanding drug-target interactions and target identification.

Vancomycin is a last-resort antibiotic for the treatment of many Gram-positive bacterial infections, while remaining inactive against Gram-negative strains.

Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…

On 22 June, Chalermwut Sriporm defended the thesis 'Franchising legal frameworks: a comparative study of the DCFR, US law and Australian law regarding franchise contracts'. The doctoral research was supervised by Jacob Hijma and Iris Houben.

Transcutaneous vagus nerve stimulation (tVNS) was tested in chronic worriers. tVNS may reduce spontaneously occurring negative thought intrusions. After a worry induction, there was no longer an effect of tVNS. tVNS did not affect physiological responding to worrying.

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

This thesis describes the Multi-site All-Sky CAmeRA (MASCARA), which consists of two small robotic telescope designed to detect exoplanets around the brightest stars in the sky.

Promotores: Prof.dr. E.F. van Dishoeck, Prof.dr. C.P. Dullemond

It has now been well established that shocks and turbulent motions in the intra-cluster medium (ICM) generated through cluster mergers can produce large-scale synchrotron emission.

Does student and teacher gender affect students’ performance and what is the role of gender stereotypes in this relation?

Politicians' statements often involve emotions, shaping public perceptions. This study highlights the role of emotions in EU foreign policy.

Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

The group Clinical Neurodevelopmental Sciences has expertise in individual differences in child development, in particular the development of psychopathology, ranging from mild to severe neurodevelopmental disorders.

Ruobin Han defended her thesis on 21 March 2017

Marc Koper’s research focuses on electrocatalysis and electrochemical surface science for sustainable energy and chemistry. Reactions of interest are the redox reactions of the oxygen/hydrogen cycle (water oxidation, hydrogen evolution), the carbon cycle (reduction of carbon dioxide, oxidation of small…

We study the physics of a broad range of biological and soft materials

Kantorowicz & Voigt examine whether federal systems, with their multiple levels of government, lead to higher constitutional compliance

Inflammatory skin diseases such as psoriasis and atopic dermatitis can severely impact both the physical and social aspect of a patient’s life. Aberrant inflammatory responses are thought to be a major causative factor in these disorders, but an abundance of different factors contribute to the development…

This article examines how the threat of terrorism has been addressed at the policy level through an analysis of a specific case in Mali.

A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.

On Friday 7 March 2025 Adam Knight successfully defended a doctoral thesis and graduated.

The Violence and Violence Prevention research group at Leiden University focuses on understanding and preventing violence in modern societies. The group offers two key educational programmes: the Minor Violence Studies and the Governance of Violence specialisation within the Master’s in Crisis and Security…

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.

Mission: The Environmental Biology department aims to increase the scientific understanding of how current and emerging anthropogenic threats affect biodiversity and ecosystem services. Through this understanding they facilitate strategic management of natural resources by addressing urgent challenges…

Promotor: Prof.dr. B.R. Katzy, Co-promotor: R. Ortt

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.

Complaints against decisions not to prosecute in socially sensitive issues.

Wout Broekema highlights how organisations not only learn from crises but also forget, losing crucial knowledge and practices over time.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

Plants are colonized by an astounding number of microorganisms that can provide different life-support functions, including nutrient acquisition and protection against (a)biotic stresses like drought or pathogen attack.

Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

How do mycobacteria subvert the defenses of host immune cells?

Can we link multiple components from herbal extracts with their biological activities?

The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.

Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.

What are the mechanisms involved in the reconciliation of value conflicts and which interventions are capable of resolving such disputes?

Atherosclerosis is a chronic inflammatory disease affecting millions of people world-wide.

From basic science to real-world interventions

Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.

On the occasion of prof Paul van der Heijden’s stepping down as Rector Magnificus and President of the Executive Board of Leiden University in 2013 the Chair bearing his name on Social Justice was established. It was a “farewell present” of the Leiden University to it’s Rector.

To meet the rising demand for minerals driven by the global shift to clean energy technologies, ensuring responsible and resilient supply chains is critical. Minerals like cobalt, lithium, and nickel for batteries, neodymium and zinc for wind turbines, and indium for solar panels are essential.

Understanding individual differences in self-regulation in boys with ODD/CD on the level of brain, cognition and behavior

This thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular…

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.