In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

The Division of BioTherapeutics at the Leiden Academic Centre for Drug Research (LACDR) is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.

Source: Br. J. Pharmacol., Volume 172, Issue 3, pp. 940-55 (2015)

The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets

A seven-metre glass tunnel, filled with running water, and equipped with speakers and cameras. An artificial river for investigating what light and sound pollution do to migrating fish.

Beneficial plant-associated microbiota, particularly those inhabiting the rhizosphere, contribute substantially to plant health through pathogen suppression, stimulation of plant defence responses, and enhanced nutrient acquisition.

A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.

Kantorowicz explores how gender stereotypes affect perceptions of leadership competence across crisis types, focusing on pandemic leadership traits.

In this thesis, we used genetically engineered mouse models to identify genes and pathways that are involved in ILC formation and in the development of resistance to FGFR-targeted therapy.

The research in Biological- and Soft-Matter Physics specialisation consists of 120 European Credit Transfer System (EC) points and includes electives (60 EC) and two research projects (60 EC).

Metastasis is responsible for over 90% of cancer-related deaths and arises from the ability of a small subset of tumor cells to detach from the primary tumor, overcome multiple biochemical and mechanical barriers, disseminate through the body, and colonize distant organs.

This webpage is for companies interested in becoming an internship partner.

The two-year master’s programme in Computer Science at Leiden University offers seven specialisations ranging from AI to Bioinformatics and Data Science. The programme combines excellent theoretical teaching with possibilities for applied work with industrial relevance.

Tussen 14 en 30 september 2022 wordt Het Land van Belofte gespeeld door Theatergroep De Kale. Het Land van Belofte neemt u mee naar de groteske verhaalwereld van middeleeuwse pelgrims naar het Heilig Land. Het Land van Belofte is gebaseerd op het zestiende-eeuwse tafelspel Schipper, Pelgrim en Post.…

Tim Koopmans is one of the great minds in the history of Dutch and European legal scholarship. He taught law as a professor in Leiden and other universities, among which Ghent, Cambridge, Utrecht. He practiced it as a judge in the European Court of Justice and Advocate-General in the Dutch Supreme Court,…

Het Nationaal Archief en het Noord-Hollands Archief onderzoekswedstrijd

Eleven Leiden researchers have been awarded an 800,000 euro Vidi grant by the Dutch Research Council (NWO). This will enable them to develop their own innovative line of research and start their own research group.

Physicist Remko Fermin from Leiden University was awarded a Rubicon grant from NWO. He will use it to study superconducting diodes that could contribute to reducing the CO2 emission of data centres.

In de maanden maart, april en mei organiseerde het programma Transparantie in Informatie, van de ministeries van Economische Zaken en Klimaat (EZK) en Landbouw, Natuur en Voedselkwaliteit (LNV), gesprekken over de veranderopgave naar een Open Departement. De sessies hadden als doel om een eerlijk en…

Tracking early human behaviour through plant processing and -exploitation.

ERC StG SAFE and SOUND has the ambition to connect the policy cycle with data generated in robot testing zones to support evidence-based policymaking for robot technologies.

Life Sciences Artificial Intelligence Data Science

Imagine that you have a chronic skin condition, characterized by red patches of itchy, scaly skin. You regularly notice people staring at your skin and sense their reluctance to shake your hand. Or imagine that you have Parkinson's Disease, causing your hands to tremble and making it difficult for you…

The ability to create objects and structures with our hands has been essential to human development. This ability is something modern society is at risk of losing. Leiden archaeologists gather knowledge about ancient processes of ‘making and creating’ over the centuries, knowledge that helps our current…

The main research theme in the group of Dennis Hetterscheid is to understand and mimic bioinorganic multi-electron processes that are relevant to our future energy infrastructure. Reduction of protons generates hydrogen that can be used as a chemical fuel. Alternatively to gaseous hydrogen, the reduction…

Within the Graduate School you can conduct your PhD research in a wide range of subjects across the Social and Behavioural Sciences, with five distinct research areas offered by its Institutes.

It is not man’s ingenuity, but rather materials that are the source of innovation and progress. This is what archaeologist Maikel Kuijpers concludes based on his research into craftsmanship and material processing in the Early Bronze Age.

Prediction of human (CNS) target site concentrations in health and disease In the vision of Prof. de Lange we will only be able to predict human (central nervous system, CNS) target site concentrations and effects if we perform systematic, condition-dependent, integrative, and strictly quantitative…

Knowledge and culture subproject 1:

The International Bachelor in Psychology (IBP) offers a broad academic development, with knowledge of several subdisciplines, such as clinical (neuro)psychology, developmental psychology, social and organisational psychology, economic and consumer psychology, cognitive psychology and health psycholo…

The Veni grant is awarded annually by NWO (Netherlands Organisation for Scientific Research). This year, multiple researchers from Leiden University and 2 researchers who will soon be working at the university will receive a Veni grant from the NWO. Thanks to this grant, which can amount to up to 320,000…

At Leiden Observatory, researchers investigate the origin of stars and their planetary systems. They detect and characterize planets around other stars, which are called exo-planets. They study how stars and planets form. And they follow molecules from interstellar clouds to nascent planet systems.…

This thesis, conducted in the framework of ERC Starting grant project BABYLON (PI: Caroline Waerzeggers), presents an investigation into Babylonian society, focusing on the city of Borsippa during Neo-Babylonian and early Persian rule (c. 620-484 BCE).

Increasing above- and belowground biodiversity in arable leek cultivation to stimulate pest control by natural enemies.

What is the relation between brain development and social and cognitive development across childhood, adolescence and adulthood?

Numerous beads and pendants of amber, jet and bone have been found in Dutch Neolithic and Bronze Age context, both in settlements and in graves. Because ornaments are personal items, they are closely linked with people’s identity.

proefdieren dierproeven universiteit leiden geneesmiddelonderzoek geneesmiddelen

‘I would never want to be treated by a computer,’ says Boudewijn Lelieveldt, Head of Radiology at the Laboratory for Clinical and Experimental Image Processing and Medical Delta professor in the Bioinformatics group at Delft University of Technology. No matter how intelligent a system, we have to continue…