4,221 search results for “leiden bio science paul” in the Public website
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Prison research
The Institute of Criminal Law and Criminology conducts extensive research on imprisonment. Sending a person to prison is the most severe form of punishment that can be applied in the criminal justice systems of European countries. In most countries, the number of prisoners has risen in recent decades.…
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Application and admission for students with a degree from a Dutch University of Applied Sciences (HBO)
Students with a Dutch HBO Bachelor’s in Biology and Medical Laboratory Research or equivalent can only be admitted to the master after completing the premaster’s programme.
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Faculty of Science and Technical University Denmark sign exchange agreement
The Faculty of Science of Leiden University and the Technical University of Denmark (DTU) signed an exchange agreement on Tuesday. This Erasmus+ student mobility agreement allows all students of the Faculty of Science and DTU students to follow courses at both universities from September 2017 on.
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Climate adaptation and biodiversity
The university is making its campuses future-proof with measures for climate adaptation and biodiversity. You can read in the Sustainability Implementation Agenda 2023–2026 how we harvest rainwater, limit heat stress and make more room for greenery.
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A podium for science
Rector Magnificus Carel Stolker will retire on 8 February. If there’s one theme running through his career, it’s the links between the University and society. In this series of pre-retirement discussions, Stolker will talk one last time to people from within and without the University. This edition…
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Building projects
Building projects Real Estate Department
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Design, synthesis and application of sulfur-containing heterocycles for the inhibition of glycosidases and glycosyltransferases
This thesis describes the design and synthesis of novel small molecules based on sulfur-containing heterocycles for the inhibition of glycosidases and glycosyltransferases related to Fabry and Pompe disease.
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Call for special sessions
We invite proposals for special sessions on interdisciplinary, under-studied, and emerging topics (deadline passed).
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Mortality and HyperImage: Visual analytics techniques for biomarker discovery in massive 3D-omics datasets
Over the past decade, several novel types of spatially resolved
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Synthesis of mycobacterial phenolic glycolipids
Het proefschrift omschrijft de chemische synthese van fenolische glycolipiden van verschillende mycobacteriën met het doel om deze te kunnen gebruiken voor immunologisch onderzoek.
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Unraveling the role of signaling networks controlled by Grainyhead like transcription factor in breast cancer subtypes
This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…
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Piecing together the regulatory puzzle: Advancing natural product discovery in Actinobacteria
Although bacteria are usually invisible to the naked eye, they are the silent force behind many processes in our daily lives.
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Exploring the Versatility of Human β-Glucosidases and Related Glycosylated Metabolites with Novel Chemical Tools
Thesis focused on uncovering the underlying mechanisms of the lysosomal storage disorders Gaucher's disease using chemical tools, biochemical assays and lipidomics.
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Determining global distribution of microplastics by using citizen science
The objective of this study is to better understand the distribution of microplastics in the environment. More specifically, we will quantify the abundance and distribution of microplastics on beaches.
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Global History of Knowledge
Our team is committed to the study of knowledge in its broadest sense, encompassing both ideas and practices in all its historical variety. We look at what people regarded as knowledge, how they created, collected, circulated and used it, also why it mattered to them, and how all this was embedded in…
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LUC 101: a personalized Q&A session with a student of Liberal Arts & Sciences
Study information, LUC 101 | Information Session
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Causing a stir: Radiative and mechanical feedback in starburst galaxies
Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf
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Staff and contact
See our staff or contact us
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Theoterrorism v. Freedom of Speech
From Incident to Precedent
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Princes and Prophets: Democracy and the Defamation of Power
On 1 June 2022, Tom Herrenberg defended the thesis 'Prosecutorial Discretion in International Criminal Justice'. The doctoral research was supervised by Prof. P.B. Cliteur and Prof. B.R. Rijpkema.
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Colloquium Ehrenfestii
The colloquia Ehrenfestii take place about once every month. This lecture series has been running since 1912.
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Vices of the Learned. Towards a Long-Term History of Scholarly Vices
Why are professors still warning their students against dogmatism, prejudice, pedantry, and other centuries-old vices? What explains the persistence of these scholarly vices across the ages?
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Symposium on Interdisciplinary Research
On 8 November 2021 YAL organized the successful symposium Interdisciplinary Research: Challenges and Opportunities.
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Research Design in Political Science: The new book by Dimiter Toshkov is now out
The new book by Dimiter Toshkov - associate professor of Public Administration at the Faculty of Governance and Global Affairs - has been recently published by Palgrave Macmillan.
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International Justice (BA Major of Liberal Arts and Sciences: Global Challenges)
Home to the International Court of Justice and the International Criminal Court, The Hague is the perfect backdrop to explore conceptions of justice in our global society. Questions of human rights, peace, security and the environment present legal and policy challenges for governmental and non-governmental…
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World Politics (BA Major of Liberal Arts and Sciences: Global Challenges)
The World Politics Major at Leiden University College The Hague examines the big ideas and the powerful forces – political, military, economic, social and cultural – that shape the world at every level, from the global to the local and everything in between. Political conflict is a key driver of many…
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Around the Rapenburg
The Around the Rapenburg walk takes you along the canal where Leiden University was founded 450 years ago.
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Neeltje BlankensteinFaculty of Social and Behavioural Sciences
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Julia FolzFaculty of Social and Behavioural Sciences
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Marloes van Moort
Faculty of Social and Behavioural Sciences
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New Science assessor cares for mental health students
More attention for internationalisation, diversity, but also the mental health of students: that’s what Marleen van Dorst would like to see change. As of 1 September, she will be the new assessor of the Faculty of Science.
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The usefulness of science: ‘Room for exchanging questions, values and ideas'
Is scientific research useful? In his dissertation, Jorrit Smit argues that in order to answer this question one should not look at, for example, prominent scholars or influential organisations, but at places where knowledge exchange and co-creation take place. Promotion 6 May.
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Signs on Paper: Unlocking the Histories of Sign Languages with AI
This PhD project investigates how automatic sign language recognition technology can be further developed to analyse static images and textual descriptions of signs.
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Direct and two-step activity-based profiling of proteases and glycosidases
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
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Chemical tools to monitor and control human proteasome activities
Promotores: H.S. Overkleeft; G.A. van der Marel Co-Promotor: B.I. Florea
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Inhibitor discovery of phospholipases and N-acyltransferases
In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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Targeting Human Proteasomes: Substrates, Inhibitors and Prodrugs
Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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Inhibitors and probes targeting mannanases
This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…
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Activity-Based Proteasome Profiling
Promotor: H.S. Overkleeft, Co-promotor: B.I. Florea
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Prepare for your studies
You’ve been accepted! Leiden University looks forward to welcoming you as a new student. Your next step is to prepare for your studies. Below you can find some tips to help you get a head start as you embark on your studies at Leiden University.
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Modeling interactions to unravel biomarkers for disease progression and treatment response
The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets
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C5 (Clever Combination of Synthetic Compartmentalization, Carbon Fixation and Compound Biomanufacturing)
Can Cyanobacteria be engineered to convert the greenhouse gas carbon dioxide into the valuable chemical isoprene?
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Hortus botanicusRapenburg 73, Leiden
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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International HouseKaiserstraat 13, Leiden
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
