On Thursday 9 november, Reijer Passchier defended his dissertation 'Informal constitutional change'. His supervisor is Professor Wim Voermans.

Our research examines mental health risk and resilience in young people. We do so by integrating cultural, social, cognitive and neurobiological factors and their interactions.

Without electronics carrying out computational tasks our daily lives would look very different. Devices such as elevators, vending machines, turnstiles, washing machines and even traffic lights use a simple form of electronic computing to switch from state to state. But, what if power supply is not…

Many important topics in computer science, such as the correctness of software, the efficiency of algorithms and the modeling of complicated systems, depend on sound theoretical underpinnings. In the Theory group, we study these fundamental building blocks and develop verification methods to prove system…

The first book ever on information-theoretically secure multiparty computation

This thesis is about cosmological inflation and its relation to observations.

The main objective of this thesis was to develop clinically relevant survival models for patients with high-grade soft tissue sarcoma of the extremities, in particular the development and validation of prediction models for use in clinical practice.

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Promotor: A. Achúcarro, Co-Promotor: G.A. Palma

Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp

This thesis contributes to studying primordial cosmology theories and their detectability in future observations.

Many important and extraordinary discoveries have been made in Leiden. Roam the city and discover the fascinating stories behind them. All you need is your smartphone!

A plasma is an ionized gas with very low electrical resistivity. As such, magnetic field lines are 'frozen in' and move with the fluid. Magnetic field lines that are linked, knotted and tangled, cannot be undone by the fluid motions.

Leiden University celebrated its 444th anniversary with a historical procession on 8 February. It celebrated this year’s Dies Natalis in time-honoured fashion with a ceremony in the Pieterskerk, but broke with tradition by sending professors out to primary schools.

Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.

The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.

Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

Children with autism spectrum disorder experience serious challenges in social functioning, which threatens their development in many areas of functioning.

The symposium is open to all registered participants and consists of a one-day programme and a poster session.

This article devises a framework to assess the degree to which human rights bodies provide duplicating or contradicting recommendations to States. Focusing on the case of torture, it creates an original database of recommendations delivered to 14 countries in the years 2012–2016. Results show that duplications…

During the early modern period, many medieval manuscripts were cut up into strips of parchment which were reused to reinforce the bindings of newly printed books. Until recently, these reused pieces of medieval manuscripts only came to light when the early modern book binding was damaged and/or subjected…

Promotor: F.H.J. Redig, Co-Promotor: W.T.F. den Hollander

How do plant defense genes get activated?

Which adolescents are more at risk of developing social anxiety disorder later in life?

Plant Sciences' contribution to the Development & Disease research theme is to unravel the processes that allow plants to adapt to changing abiotic and biotic environmental conditions or stresses, with the aim to contribute to the sustainable production of food, flowers and bio-based products using…

Eleven researchers from Leiden University have been awarded an Open Competition Domain Science ENW XS grant by the Dutch Research Council for their research projects. They are researching how to make software faster and greener, improve cancer detection and reduce anxiety by manipulating the biological…

The effects of many treatments are determined, to a significant degree, by factors other than the medicine or treatment itself. For example, placebo effects can be equal to the effect size of for example antidepressants or painkillers. Contributing factors are the trust placed in the doctor, the expectation…

Open online education has become a highly popular method of education. The current project aims to further our knowledge of how open online courses can be best designed to be consistent with human learning mechanics and facilitate meaningful learning.

Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.

Source: PLoS ONE, Volume 10, Issue 3 (2015)

Research in the group Clinical Neurodevelopmental Sciences is focused on understanding and influencing developmental mechanisms in children and adolescents.

Miriam Cohen defended her PhD dissertation entitled “Reparations for International Crimes and the development of a Civil Dimension of International Criminal Justice” on 28 June 2017. She wrote her thesis under the supervision of Professor L.J. van den Herik and Professor C. Stahn.

In this research group, headed by Prof. Erik Danen, the aim is to unravel cellular signaling mechanisms in normal and diseased cells, with a long-standing interest in cell adhesion signaling. In complex multicellular organisms such as ourselves, a division of labor emerges where different tissues and…

Promotor: M. Ubbink, Co-Promotor: R. T. Dame

This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.

In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.

‘Schiedsgerichte in den Aussenverträgen der EU. Neue Entwicklungen unter Einbezug der institutionellen Verhandlungen Schweiz–EU’, Jusletter 28 May 2018

Aluminium-based adjuvants, such as aluminium hydroxide and aluminium phosphate, are well-known for their immune-stimulating properties.

The research groups within the biological, soft and complex systems research area study the physics of a broad range of biological and soft materials. This spans both experimental and theoretical research.

The dissociative chemisorption of a molecule on a transition metal surface represents a rate-limiting step in many heterogeneously catalyzed processes, whereby most chemicals are made. In spite of the importance of this reaction, an accurate first principles approach to modeling it does not yet exist.…

From a meaningless block of plastic to an advanced component that contributes to the energy transition. The technicians and scientists of our faculty think it out in detail and make it a reality. This special project shows that they need each other.