2,303 search results for “Kovalevskaia S V” in the Public website
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Assembling anisotropic colloidal building blocks
This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.
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On metrics and models for multiplex networks
In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.
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Quality-driven multi-objective optimization of software architecture design: method, tool, and application
Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M.R.V. Chaudron, Co-Promotor: M.T.M. Emmerich
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Analecta Praehistorica Leidensia
The APL (Analecta Praehistorica Leidensia) is published once a year and showcases the increasingly diversity of research conducted at the Faculty of Archaeology. The APL currently forms a showcase for the faculty as a whole in which all employees can publish their research. By alternatingly publishing…
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Pre-Colonial and Post-Contact Archaeology in Barbados
This volume provides one of the most comprehensive overviews of the archaeology of a single Caribbean island yet published. Drawing together scholars from the Caribbean, north America and Europe, all working from a range of disciplines within the broader scope of archaeology, and drawing upon recent…
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Philippine Confluence: Iberian, Chinese and Islamic Currents, C. 1500-1800
Situated at the crossroads of the Indian and Pacific Oceans, the Spanish Philippines offer historians an intriguing middle ground of connected histories that raises fundamental new questions about conventional ethnic, regional and religious identities.
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Nanoparticulate Impurities in Pharmaceutical-Grade Sugars and their Interference with Light Scattering-Based Analysis of Protein Formulations
PURPOSE: In the present study we investigated the root-cause of an interference signal (100-200 nm) of sugar-containing solutions in dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA) and its consequences for the analysis of particles in biopharmaceutical drug products.
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Sustainability Award
The moment is there: LUGO can finally announce the winner of the Sustainability Award 2020!
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Finding a supervisor
Once you have decided on your field of research, you should start looking for a supervisor as early as possible.
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Sustainability Award
The moment is there: LUGO can finally announce the winner of the Sustainability Award 2020!
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In vivo fluorescence imaging of IgG1 aggregates after subcutaneous and intravenous injection in mice
PURPOSE: To monitor the biodistribution of IgG1 aggregates upon subcutaneous (SC) and intravenous (IV) administration in mice and measure their propensity to stimulate an early immune response.
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Inhibitors and probes targeting mannanases
This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…
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Development of a Transgenic Mouse Model to Study the Immunogenicity of Recombinant Human Insulin
Mouse models are commonly used to assess the immunogenicity of therapeutic proteins and to investigate the immunological processes leading to antidrug antibodies. The aim of this work was to develop a transgenic (TG) Balb/c mouse model for evaluating the immunogenicity of recombinant human insulin (insulin)…
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Intercellular Skin Barrier Lipid Composition and Organization in Netherton Syndrome Patients
Netherton Syndrome (NTS) is a rare genetic skin disease caused by mutations in the serine protease inhibitor Kazal-type 5 gene, which encodes the lympho-epithelial Kazal-type-related inhibitor. NTS patients have a profound impaired skin barrier function. Because SC lipids play a crucial role in the…
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Abiotic depletion in LCIA
Possible improvements for the assessment of abiotic depletion in LCA.
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CWTS
The Centre for Science and Technology Studies (CWTS) is an interdisciplinary research institute at Leiden University that studies scientific research and its connections to technology, innovation, and society.
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Elizabeth Stuart, Queen of Hearts
Elizabeth Stuart is one the most misrepresented – and underestimated – figures of the seventeenth century. Daughter of James VI & I, she was married to Frederick V, Elector Palatine in 1613 – they were crowned King and Queen of Bohemia in 1619, only to be deposed and exiled to the Dutch Republic in…
- Organisation
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Cryo-EM of cholera infection
The structure of bacterial cells provides crucial clues about their interaction with their host. What are the key structural features of a bacterial cell that determine pathogenicity? What roles do these structures play in the life cycle, and how do they change during the infection process?
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Modulation of Stratum Corneum Lipid Composition and Organization of Human Skin Equivalents by Specific Medium Supplements
Our in-house human skin equivalents contain all stratum corneum (SC) barrier lipid classes, but have a reduced level of free fatty acids (FAs), of which a part is mono-unsaturated. These differences lead to an altered SC lipid organization and thereby a reduced barrier function compared to human skin.…
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Biodiesel production using blue-green cyanobacterium Synechococcus elongatus PCC 7942
Promotores: Prof.dr. C.A.M.J.J. van den Hondel, Prof.dr. V. Meyer (Technische Universität Berlin)
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Michel Orrit Lab - Single Molecule Optics
Since the early 1990s, one can isolate the optical signal of a single molecule and single-molecule spectroscopy has quickly grown into an important research field.
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Development and application of cryo-EM tools to study the ultrastructure of microbes in changing environments
Cryogenic electron microscopy (cryo-EM) is a powerful technique used to visualize the inside of cells and to study specific protein complexes. Within this thesis, I describe the use of various cryo-EM techniques to gain insight into the structural changes of the human pathogen, Vibrio cholerae, as it…
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Enhancing the societal impact of academic publications (Creatieve Industrie – NWO KIEM)
The central goal of academic publishers is the dissemination of the results of research and scholarship. Their audiences can generally be divided into two categories. Academic publications are firstly made accessible to the scholarly community, so that these texts can form the input for new academic…
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Ana Achúcarro Group - The Early Universe
We explore the particle physics and quantum world at the time of the big bang.
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Structural Properties of Single Server Queueing Systems: Efficient Methods via Lumping and Dynamic Programming
This thesis consists of two main parts. The first part (Chapters 2 and 3) deals with a class of Markov process called Quasi-Skipfree (QSF) processes.
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Laboratory studies of Water Ice in Space
Astronomical observations of cold regions in the universe show a rich inventory of ices. Part of these ices may end up on planets like our own, but in that journey they will be exposed to considerable amounts of radiation.
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Explant cultures of atopic dermatitis biopsies maintain their epidermal characteristics in vitro
Atopic dermatitis (AD) is a common inflammatory skin disorder characterised by various epidermal alterations. Filaggrin (FLG) mutations are a major predisposing factor for AD and much research has been focused on the FLG protein.
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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Extracurricular
Get the most out of your studies at Leiden University by taking part in our extracurricular activities.
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Extra-curricular
Get the most out of your studies at Leiden University by taking part in our extracurricular activities.
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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Extracurricular
Get the most out of your studies at Leiden University by taking part in our extracurricular activities.
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EC and grading information
Learn more about your course load, study credits and the grading system in place at Leiden University.
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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Career preparation
Leiden University offers you several services related to career orientation and job application skills.
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Video's
View the aftermovies of the run here.
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Video's
On this digital video wall, you can find the videos provided by several attendees of the XY workshop 2022.
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Working Paper Series
The Grotius Centre Working Paper Series is an occasional series through which researchers in the Grotius Centre can publish the unedited versions of manuscripts that have been accepted for publication by journals and books.
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Revealing Śiva’s Superiority by Retelling Viṣṇu’s Deeds
Sanne Dokter-Mersch defended her thesis on Thursday 15 April 2021.
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Pre- Master's Programme
The pre-master’s programme helps students remove deficiencies to meet the admission requirements to the master’s programmes of the Institute of Public Administration.
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Master's Open Day
Want to study abroad? Visit the Master’s Week of Leiden University and find which master's programme taught in Leiden or The Hague is right for you.
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