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50 search results for “Kleiman Devra G” in the Public website

• 
  G Dijkman

  Faculteit Geneeskunde

• 
  G Tavilla

  Faculteit Geneeskunde

• 
  G Jukema

  Faculteit Geneeskunde

• 
  G Kleiverda

  Faculteit Geneeskunde

• 
  G Trimbos-Kemper

  Faculteit Geneeskunde

• 
  G van Drunen

  Faculteit Geneeskunde

• G. Rozenberg Research Award Leiden Institute of Advanced Computer Science (LIACS)

  In 2022, LIACS created the G. Rozenberg Research Award in honor of its 25th anniversary. This new award is intended for promising PhD students of LIACS.

• 
  Johannes (Hans) G.E.M. Fraaije Professor emeritus of Physical chemistry

  Science

• Jose G. Vallarino 16th International Metabolomics Workshop

  PhD at Molecular Biology and Biochemistry Department, University of Malaga - Spain

• Erica G. Wilson 16th International Metabolomics Workshop

  PhD at the Natural Products Laboratory, Institute of Biology, Leiden University - the Netherlands

• Prof. G. Rozenberg Leiden Institute of Advanced Computer Science (LIACS)

  LIACS prof. Grzegorz Rozenberg is one of the world leaders in research on Theoretical Computer Science and Natural Computing. He is often called the guru of Natural Computing.

• Prof. G. Rozenberg Leiden Institute of Advanced Computer Science (LIACS)

  LIACS prof. Grzegorz Rozenberg is one of the world leaders in research on Theoretical Computer Science and Natural Computing. He is often called the guru of Natural Computing.

• Political Ideas of B.G. Tilak Research output

  On 12 April 2022 Alok Oak successfully defended a doctoral thesis and graduated.

• G.F. Stout and the Psychological Origins of Analytic Research output

  The philosopher and psychologist G.F. Stout was the teacher of Moore and Russell around 1894. This book shows that Stout's ideas have played a role in Moore and Russell's development from their early idealism towards analytic realism, where Stout's ideas often find their origin in early phenomenolog…

• Corpora Non Agunt Nisi Fixata: Ligand Receptor Binding Kinetics in G Protein-Coupled Receptors Research output

  The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.

• Better ligands for G Protein-Coupled Receptors Research project

  The receptor nomenclature committee of IUPHAR, the International Union of Pharmacology, has several subgroups. Among these are a few that our division is involved in, those for adenosine, nicotinic acid, and GnRH receptors.

• interaction between the adenosine A2B receptor and the C-terminus of different G protein α-subunits. Research output

  Source: Purinergic Signal., Volume 10, Issue 3, pp. 441-53 (2014)

• The activation mechanisms of G protein-coupled receptors: the case of the adenosine A2B and HCA2/3 receptors Research output

  Promotor: A.P. IJzerman

• Covalent inhibitors of G protein-coupled receptors: the case of adenosine receptors Research project

  Supervisor: Xue Yang

• explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors Research output

  Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…

• Indanes-Properties, Preparation, and Presence in Ligands for G Protein Coupled Receptors Research output

  The indane (2,3-dihydro-1H-indene) ring system is an attractive scaffold for biologically active compounds due to the combination of aromatic and aliphatic properties fused together in one rigid system.

• Islam at 250: Studies in Memory of G.H.A. Juynboll Research output

  Islam at 250: Studies in Memory of G.H.A. Juynboll is a collection of original articles on the state of Islamic sciences and Arabic culture in the early phases of their crystallization.

• the NPxxY(x)(5,6)F motif and helix 8 of the adenosine A(2B) receptor in G protein coupling Research output

  Source: Biochem Pharmacol, Volume 95, Issue 4, pp. 290-300 (2015)

• Allosteric modulation by sodium ions and amilorides of G protein-coupled receptors Research output

  Promotor: A.P. IJzerman

• Allosteric modulation by sodium ions and amilorides of G protein- coupled receptors Research output

  Promotor: A.P. IJzerman

• 
  Renetta Bos External PhD candidate

  Faculteit Rechtsgeleerdheid

• 
  Adriaan IJzerman Professor emeritus Pharmacochemistry

  Science

• In Memoriam Emeritus Professor G. van Dijk News - 22 April 2022

  Gerrit van Dijk was born on 14th August 1939 in Kampen. He studied Mathematics in Utrecht where he also received his PhD in 1969 on the thesis ‘Spherical functions on the p-adic group PGL(2)’. His supervisor was prof. dr. T.A. Springer. The academic year 1969-1970 he spent in Princeton, at the Institute…

• 
  Maria van der Schaar Senior University Lecturer History and Philosophy of Logic

  Faculty of Humanities

• The good? The bad? The mutant! Characterization of cancer-related somatic mutations and identification of a selectivity hotspot in adenosine Research output

  G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

• 
  Natalia Ortiz Zacarias Postdoctoral Researcher

  Science

• 
  Laura Heitman Professor Molecular Pharmacology

  Science

• Leiden Law Cast #3: Damaged trust in claims policy with Dr G. Kuipers News - 20 January 2022

  Leiden Law Cast is a podcast made by Leiden Law School, Leiden University, for everyone who wants to learn more about current legal issues.

• The ins and outs of ligand binding to CCR2 Research output

  Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: Dr. L.H. Heitman

• Biophysical characterization of membrane protein-small molecule interactions Research output

  Promotor: M. Ubbink, Co-promotor: G. Siegal

• Clavis Aurea? Structure-enabled approaches of identifying and optimizing GPCR ligands Research output

  Promotores: A.P. IJzerman, H.W.T. van Vlijmen

• Sensing Transport Research output

  Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

• Leiden Law Cast #1: Child benefits scandal & compassion with Professor A.G. Castermans News - 17 December 2021

  Leiden Law Cast is a podcast made by Leiden Law School, Leiden University, for everyone who wants to learn more about current legal issues.

• The road to insurmountability: Novel avenues to better target CC Chemokine receptors Research output

  This thesis explores different avenues to develop insurmountable antagonists for CC Chemokine Receptors, such as CCR1, CCR2 and CCR5.

• Towards improved drug action : target binding kinetics and functional efficacy at the mGlu2 receptor Research output

  During the course of drug discovery translational steps are made.

• A chemical biology approach for targeting of ligand-drug conjugates Research output

  Promotores: Prof.dr. H. S. Overkleeft, Prof.dr. G. A. van der Marel

• Whole-cell biosensor for label-free detection of GPCR-mediated drug responses in personal cell lines Research output

  Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)

• Affinity-based profiling of the adenosine receptors Research output

  The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.

• Valedictory lecture prof.mr. W.G. Huijgen Event - 10 February 2023

  Valedictory lecture

• Political Ideas of B.G. Tilak Event - 12 April 2022

  PhD defence

• Cancer-induced somatic mutations in G protein-coupled receptors Event - 20 September 2022

  PhD defence

• Day Public Administration: International and European Governance (IE&G) Event - 7 May 2019

  Study information

• explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors Event - 15 February 2022

  PhD defence

• Tailored medicines News - 6 December 2017

  Medicines do not follow the one size fits all principle, because genetic differences can influence their efficiency. That is what research by PhD candidate Julia Hillger shows. She defends her PhD dissertation Take it Personal on Thursday 7 December.

• Laura Heitman appointed as Professor of Molecular Pharmacology News - 26 November 2020

  As of 1 November, Laura Heitman has been appointed full Professor of Molecular Pharmacology at the Leiden Academic Centre for Drug Research (LACDR). Heitman has been working on the understanding and improvement of drug-receptor interactions in early drug discovery. ‘My ultimate aim is to make medicines…