762 search results for “Brazilian Journal of Medical and Biological Research” in the Public website
- About this minor
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Weathering the Ice Age
Where did species survive the cold cycles of the current Ice Age?
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Research: interest in teacher training degree in The Hague
Like other big cities, The Hague is facing a severe teacher shortage. A new university teaching degree might help solve this problem. Research has shown that secondary school students would be interested in this option.
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Polypept(o)ide-based Cylindrical Polymer Brushes as Multifunctional Drug Delivery Systems
The polypept(o)ide hybrid material attracted more and more attention over the past decade by combining the multifunctional characteristics of polypeptides with the shielding characteristics of polypeptoid-pSar possessing similar properties as a shielding material as polvethylene glycol(PEG). Polysarcosine…
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Symposium 2023: Reaction mechanisms in heterogeneous, inorganic and biological electro(photo)catalysis
Conference
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Latest hardware for computer research on medical imaging
The LIACS Media Lab has received a research grant from the worldwide leading graphics hardware company NVIDIA. The grant exists of newly developed hardware utilizing thousands of processors. LIACS researchers will use it to investigate deep learning in understanding imagery from sources such as MRI…
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Fundamental Research in Chemical Biology
Chemical biology research at the Leiden Institute of Chemistry is aimed at understanding biological processes at the molecular level to strengthen the knowledge base of human health and disease. The approach to achieve this goal is a fundamental chemical one; with the aid of chemical probes biological…
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Influencing your health with your behaviour and thoughts
Psychological processes have a major effect on the course of a disease and the effects of medical treatment. Researchers in the field of Psychoneurobiology examine the interactions between body and mind. They investigate the effects of stress as well as the effect of placebos and nocebos, which can…
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Mapping health and well-being research
Exploring the landscapes of mental health and cardiometabolic research.
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Understanding functional dynamics and conformational stability of beta-glycosidases
Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.
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Direct and two-step activity-based profiling of proteases and glycosidases
Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel
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Overview
Our research is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Theoretical Physics
In the spirit of 'unity in diversity', our objective is to promote insight into and appreciation for the wonder that the same physical laws and mathematical concepts apply to the whole of nature, from the largest to the smallest energy and length scales. We strive for the application of abstract theoretical…
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Research
Within the Chinese medicine, more than 80% of the constituents of the preparations are derived from plants. Like any other organism, plants are constantly interacting with their changing and often harsh environment during the various phases of their life cycle.
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Medical Delta professor: ‘You can talk about collaboration until the cows come home but at some point, you actually have to start doing it’
Patients and healthcare providers use Remote Patient Management platforms to exchange information with each other. New methods like this are desperately needed to future-proof our healthcare systems. Professor Maaike Kleinsmann is working to scale up these systems and implement them nationwide.
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e-infrastructure for metabolomics
an integrated, secure, permanent, on-demand service-driven, privacy-compliant and sustainable e-infrastructure for the processing, analysis and information-mining of the massive amount of medical molecular phenotyping and genotyping data that will be generated by metabolomics applications now entering…
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Placebo research: Pharmacological conditioning
The major aim is to examine the potential of learning the body to produce a similar physiological (autonomic, neuroendocrine, or immune) and physical (e.g., desensitization of persistent physical symptoms) response to placebo medication than to active medication (pharmacological conditioning). If proven…
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Biological Origami at molecular level: folding a single protein
Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With an unprecedented approach, the team was able to study the folding of a single…
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A dilemma: When and how to use the concept of “culture” in medical anthropological practice?
When and how to use the concept of “culture” . To medical anthropologists this is a core question, but also a challenging one.
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Impact factor for open access journal Research & Politics (RAP)
Research & Politics (RAP) is a peer-reviewed open access journal which focusses on research in political science and related fields through open access publication of the very best cutting-edge research and policy analysis. The journal achieved a high score for the impact factor, which puts it in 49th…
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Diego Garlaschelli Group - Econophysics and Network Theory
We study the structure, dynamics and physics of complex networks emerging from the intricate interconnectedness of the constituents of large systems.
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PhD Theses
A full overview of MCBIM PhD theses.
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Career prospects
The knowledge and skills you will acquire will qualify you for many different jobs. Possible careers include: researcher of learning, behavioural and emotional problems in children, or designer of prevention and intervention programmes.
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Exaggeration in medical news starts with the press release
Medical research is often exaggerated in the news. Medical journalists are not the only ones guilty of such sloppiness; results are also often exaggerated in academic press releases. This was the conclusion of a study by researchers from Leiden University Medical Center (LUMC) and Leiden University,…
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A multi-million grant to keep the biological clock healthy
Dutch researchers are joining forces to conduct research together with a series of societal partners to keep the biological clock healthy in our modern 24-hour society. The BioClock consortium will receive a research grant of no less than 9.7 million euros for this. It is one of the projects that receive…
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About us
All living creatures have to cope with environmental demands and threats that challenge their physical or emotional homeostasis.
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Structure-kinetics relationships of Capadenoson derivatives as adenosine A1 receptor agonists
Source: Eur J Med Chem, Volume 101, pp. 681-91 (2015)
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Screening of animal venoms for antimicrobial compounds
Can animal venoms yield novel antimicrobial peptides?
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The neurobiology of depression and the relation between stress, mental health, ageing and chronic illness
I want to understand the overlap between physical health, mental health, and healthy aging and whether/how stress (behaviorally and biologically) may tie these concepts together.
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Patterns of Paleomobility in the Ancient Antilles
Patterns of paleomobility in the Caribbean were studied through an inter-disciplinary approach using a combination of archaeological, osteological, mortuary, and isotopic data.
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Synthesis of chemical tools to study the immune system
This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.
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Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists
Source: Org Biomol Chem, Volume 13, Issue 8, pp. 2407-22 (2015)
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper, Co-Promotor: S.C.A. de Jager
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Affinity-based profiling of the adenosine receptors
The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.
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Research
Physicists at the Leiden Institute of Physics (LION) conduct fundamental research into physical phenomena. They are inspired by curiosity and the desire to know more about the world in which we live. This research has always paved the way for new practical applications. These are something that the…
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Brains react differently to ADHD medication than expected
A tried and tested medication for treating ADHD works differently than expected in the brains of healthy individuals during rest: rather than stimulating brain activity, it suppresses it.
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Why do we use laboratory animals?
We use laboratory animals to address research questions, but only when there is no alternative and the question cannot be answered in any other way. Read here why we conduct animals experiments.
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Research
Research at the Grotius Centre for International Legal Studies is primarily carried out under its Research Programme ‘Exploring the Frontiers of International Law’.
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Research
Research at the Macromolecular Biochemistry group is comprised of the following research themes:
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Medical Delta professor Ariane Briegel: 'I love working with people from different backgrounds'
Multidrug-resistant pathogens and worldwide pandemics are increasing, making infectious diseases more prevalent. To develop new treatments, deeper knowledge of the interaction between bacteria and human cells is required. Ariane Briegel recently became a Medical Delta professor and studies such path…
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Bioorthogonal Chemistry: Applications in Activity-Based Protein Profiling
The close interaction between organic chemi stry and biology goes back to the late 18th century, when the modern natural sciences began to take shape. After synthetic organic chemistry arose as a discipline, organic chemists almost immediately began to pursue the synthesis of naturally occurring compounds,…
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Ubar Kampung
The Sundanese people, the largest ethnic group in West Java, have been using traditional medicine for a long time. Known as ubar kampung, Sundanese indigenous knowledge, beliefs and practices of traditional medicine are based on local people’s knowledge and use of Medicinal, Aromatic, and Cosmetic (MAC)…
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Cuba
This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with the University of Havana.
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4D Picture project
Helping cancer patients with treatment choices.
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Research
An overview of the research at the Biologics Formulation group
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Fires, Food and the Evolution of Human Detoxification Capabilities
A study by a Leiden-Wageningen group shows that present-day humans are biologically poorly equipped to deal with the toxins they are regularly exposed to in smoky environments: compared to earlier hominins, we modern humans are probably even worse off. The study appeared in Molecular Biology and Evolution.…
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Education
The Leiden Institute of Physics (LION) offers bachelor and master level education in physics at Leiden University.
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Why Leiden University?
We are committed to provide you with meaningful, rigorous and quality graduate experiences in a personalized environment with a cutting edge research infrastructure and internationally renowned supervisors.
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Dual Medical Delta appointment for six Leiden professors and one lecturer
Six professors and one lecturer from Leiden University have officially been appointed Medical Delta professors or lecturers.
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Research
Research at Leiden Law School means research at the highest level. Leiden Law School has eight broad research programmes and one specific ‘profile area’: Interaction between legal systems - which aims to understand the complex interaction between the various levels of jurisdiction and to solve the resulting…