What are the biological effects of Chinese herbal medicine in regulation of cancer cell metastasis?

This project is situated within the context of an innovation of the biology curriculum in Dutch secondary schools. The main purposes are (1) to clarify the relation between teachers’ practical knowledge and the decisions they make when planning and implementing their lessons and (2) to develop a professional…

An attractive feature of the MSc Chemistry programme at Leiden University is the great flexibility of the study programme, allowing students to put together a tailor-made programme following their personal interests. Within the limits set by the programme, students can make their own choices and adjust…

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Many important topics in computer science, such as the correctness of software, the efficiency of algorithms and the modeling of complicated systems, depend on sound theoretical underpinnings. In the Theory group, we study these fundamental building blocks and develop verification methods to prove system…

This thesis describes a study from both a theoreticaL and an experimental point of view.

Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.

Promotor: H.V.J. Linnartz

PhD defence

Promotor: Prof.dr. E. F. van Dishoeck, Co-promotor: A. N. Heays

Leiden researchers have found minute movements in the laccase enzyme. This discovery could lead to the development of much more efficient biofuel cells. Publication in Biophysical Journal.

Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

Professor emeritus of Animal Behaviour Carel ten Cate is awarded honorary membership by the Dutch Society for Behavioural Biology (NVG). He received the honour for his activities for the Society and the discipline of behavioural biology.

The mission of the Plant Sciences cluster is to contribute to the sustainable production of high-quality crops, flowers and high-value bio-based products, and to contribute to the maintenance and restoration of biodiversity in natural ecosystems. This is realised by generating fundamental knowledge…

The Sundanese people, the largest ethnic group in West Java, have been using traditional medicine for a long time. Known as ubar kampung, Sundanese indigenous knowledge, beliefs and practices of traditional medicine are based on local people’s knowledge and use of Medicinal, Aromatic, and Cosmetic (MAC)…

The formation and evolution of galaxies is fundamentally driven by the formation of new stars out of cold gas.

Promotores: G.R. de Snoo, W.T. de Groot, Co-promotor: C.J.M. Musters

Promotor: E. Bouwman, Co-Promotor: S. Bonnet

What happens in our bodies when we care for children? And why are some people more caring than others?

Although bacteria are usually invisible to the naked eye, they are the silent force behind many processes in our daily lives.

Promotor: Prof.dr. G.P. van Wezel

Almost all bacteria are enveloped by a cell wall that provides cellular protection.

The aim of this work was to study the applicability of antigen-coated pH-sensitive microneedle arrays for effective vaccination strategies. Therefore, a model antigen (ovalbumin) was coated onto pH-sensitive (pyridine-modified) microneedle arrays to test pH-triggered antigen release by applying the…

Chapter 2 describes a post-synthetic methodology to introduce a fluorescent label in highly lipophilic, Pam3Cys based conjugates.

Promotor: H.S. Overkleeft, Co-promotor: B.I. Florea

Promotores: W. Jiskoot, F. Ossendorp

This master specialisation is ideally suited as a basis for starting a research career at a university or research institute and for a position in a bioscience-based company.

Are you interested in taking up an extra challenge during your master’s programme? Have you thought about developing your personal leadership style?

Leiden University offers you several services related to career orientation and job application skills.

In Leiden University's video series on Leiden and The Hague as student cities, students interview each other at their favorite spots. In the fifth video of this series, archaeology student Azra spoke with Biology student Floris in Naturalis Biodiversity Center.

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

Promotor: J.G.E.M.Fraaije, Co-promotor: A. Kros

Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…

How do plants lure microscopically small 'support teams' into their roots for protection against diseases? And what functions are activated in the microbes and the plants?

Leiden Biology student Pam Engelberts received the annual award for being the best BSc-student in 2016 from the “Stichting Professor Dr. K. Bakker-fonds”.

Developing new medicines is one of modern science's most significant hurdles, a process marked by high costs, long timelines, and frequent failures of promising candidates.

Leiden Biology student Bregje Brinkmann received the annual award for being the best BSc-student in 2014 from the “Stichting Professor Dr. K. Bakker-fonds”.

Animal diet studies are critical for understanding ecological processes such as trophic interactions, energy flow, and nutrient cycling. By examining what animals consume, ecologists gain insights into species specialization, predator-prey relationships, and ecosystem management.