Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…

Promotor: Prof.dr. T.H.W. Bäck

Promotor: Prof.dr. P.G.L Klinkhamer

Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…

This book provides an exploration into the historical transformations of women's interactions with state police in the Western world from 1800 to 1950.

Farming practices, food production, and the agricultural potential of the Late Bronze Age (1600-1200 BCE) Argive Plain, Greece

This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.

This thesis manuscript explores the use of video games as tools for conceptual exploration and academic research.

This dissertation focuses on the overt marking of φ features encoded on perfective active auxiliaries in a group of Southern Italian dialects.

On the 23rd of January, Anastasiia Ionova successfully defended her doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Anastasiia on this achievement.

Dionysius of Halicarnassus and Augustan Rome: Greek culture in the Roman world.

In this thesis, the role of mast cells in atherosclerosis and novel therapeutic strategies to inhibit atherosclerosis progression are discussed. The first part of the thesis specifically focuses on the relation between mast cells and advanced human atherosclerotic plaque characteristics.

In this thesis,

Promotor: J.P. Abrahams, Co-promotor: T. Grüne

This dissertation investigates A'-dependencies in Standard German, Zurich German and Dutch where the dislocated constituent is indirectly, i.e. not transformationally, related to the position where it is interpreted. The analysis is carried out within the Principles & Parameters framework.

The research described in this thesis centered on retaining exo-β-glucosidases implicated in health and disease, in particular the human inherited lysosomal storage disorder, Gaucher disease (GD).

We have studied the impact of particle shape anisotropy, multivalent interactions and flexibility on systems of micron-sized colloidal particles.

The Iseum Campense, the impressive sanctuary for Isis and the Egyptian gods on the Campus Martius and arguably one of ancient Rome’s most notable absent presences, is a monument central to various debates.

The Role and Effectiveness of the G20. In this article, published in The Changing Global Order part of the United Nations University Series on Regionalism book series, author Jaroslaw Kantorowicz discusses the evolution of the G20.

This book by Damien van Puyvelde provides the first comprehensive English-language account of France's modern foreign intelligence and explores its evolution, operations, and role in global security.

Science is typically a patchwork of research contributions without much coordination. Especially in clinical trials, the follow-up studies that we do fail to be the most promising.

Few events have influenced our global order as intensely as the events of September 11, 2001.

ChEMBL is a large-scale drug discovery database containing bioactivity information primarily extracted from scientific literature.

The thesis describes the use of electron paramagnetic resonance (EPR) spectroscopy, in continuous wave and pulse modes, to address the interaction of α-Synuclein (αS) with membranes and the aggregation of αS.

To meet the rising demand for minerals driven by the global shift to clean energy technologies, ensuring responsible and resilient supply chains is critical. Minerals like cobalt, lithium, and nickel for batteries, neodymium and zinc for wind turbines, and indium for solar panels are essential.

This article presents the findings of an explanatory study into the perceptions of Dutch Muslims in The Hague concerning pre-emptive counter-extremism and de-radicalisation policies.

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On the 25th of February, Peng Wu successfully defended his doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Peng on this achievement.

On the 17th of September, Jermy Balukh successfully defended a doctoral thesis and graduated. The Leiden University Centre for Linguistics congratulates Jermy on this achievement!

Article by Dennis Broeders in the Journal of Cyber Policy on the (im)possibilities of addressing election interference and the public core of the internet in the UN GGE and OEWG.

How do learners engage during project-based learning (PBL) and what is the impact of PBL on their learning outcomes?

Material circularity and energy efficiency are highly relevant and intertwined issues for the transition towards a carbon-neutral and circular built environment. In the Netherlands, the building sector has been rendered a priority towards a circular and low-carbon society.

Oxford University Press has published a revised and expanded edition of The Morphology of Dutch (first edition published in 2002).

Valentina Carraro explores the relationship between overlapping UN human rights institutions, specifically the treaty bodies and the Universal Periodic Review (UPR)

Pursuing Whiteness in the Colonies offers a new comprehension of colonial history from below by taking remnants of individual agencies from a whiteness studies perspective. It highlights the experiences and perceptions of colonisers and how they portrayed and re-interpreted their identities in Afric…

This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.

How an initially valueless object becomes worth hundreds of millions. And vice versa.

Promotor: G.R. de Snoo

Promotor: S.J. Edixhoven, Co-promotor: R.S. de Jong

Growth and development affect the metabolism of drugs administered to neonates, infants, and children.

Promotor: S.M. Verduyn Lunel, Co-promotores: M.F.E. de Jeu, B. de Pagter

The applications of studying the early development of insects range from agriculture to material science.

This thesis is a collection of theoretical works aiming at adjusting quantum algorithms to the hardware of quantum computers.

Inspired by natural photosynthesis, perovskite-based photoelectrochemical (PEC) systems are being developed for artificial photosynthesis, aiming to enhance solar-to-hydrogen conversion for green energy.

This volume sees the publication of fifty-six early Old Babylonian letters from ca. 1880 BCE. They were found by legendary Iraqi archaeologist Taha Baqir in 1941 at the site of Tell ed-Dēr, ancient Sippar-Amnānum, in central Iraq.

Outflows are crucially important for the gas budget and evolution of luminous star-forming galaxies and AGNs, with observed mass outflow rates of the same order as the star formation rate. Greater star formation and black hole growth lead to more intense feedback and outflows, resulting in self-regulated…

Promotor: W. Jiskoot, Co-promotor: H.A. Every

The theoretical explanation of cosmic acceleration is nowadays one of the biggest puzzles in cosmology.

According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).

The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.