Promotor: A. Doelman, Co-promotores: P.J.A. van Heijster; A. Zagaris

This thesis mainly focuses on cross-modal retrieval and single-modal image retrieval via deep learning methods, i.e. by using deep convolutional neural networks.

Despite being the second largest transmembrane protein family after GPCRs, the SLC superfamily has only gained significant attention in early drug development over the past decade.

Autopaghy is an intracellular degradation system which targets cytosolic components to lytic compartments for degradation and recycling of the building blocks of the cell.

The experiences of ethnic ‘Other’ females have – until recently – been widely overlooked in the study of sport. There continues to be a need to produce critical scholarship about ethnic 'Other' girls and women in sport and physical culture, in order to represent their complex, multifarious and dynamic…

When a star is born in our Galaxy, it is quite likely that it has formed within a massive cluster, which hosts numerous high-mass stars bathing their lower mass neighbours in UV radiation.

Does the δ-machine have higher accuracy than the other feature-based classifiers in some conditions?

In this article, Adriana Cerdeira and Dovile Rimkute explore how certain dynamics shape banks' behaviour.

There are a number of problems in philosophy that seem to share a similar possible solution: 'Why do promises and contracts bind?', 'Why ought citizens and judges obey the law?' and 'Can we realize the gains to be made from cooperation?'. All three problems (as well as some others) share a possible…

Source: J Med Chem, Volume 57, Issue 8, pp. 3213-22 (2014)

KNOWMAK project aims at developing a web-based tool, which provides interactive visualisations and state-of-the-art indicators on knowledge co-creation in the European Research Area (ERA).

Stratigraphy, Palaeoenvironment and Archaeology of the Middle and Late Pleistocene Deposits.

Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…

Clustered Neighbourhood Settlements of the Central Anatolian Neolithic ca. 8500-5500 Cal. BC

How have British cities changed in the years since the Second World War? And what drove this transformation? This innovative new history traces the development of the post-war British city, from the 1940s era of reconstruction, through the rise and fall of modernist urban renewal, up to the present-day…

The research project focuses on teachers’ learning motivation and learning performance in professional learning activities.

This new volume, published 19 November 2020, - within the series 'Intersections' -, explores the concept of magnificence as a social construction in seventeenth-century Europe. Although this period is often described as the ‘Age of Magnificence’, thus far no attempts have been made to investigate how…

This article presents a new dyadic approach to studying voting behaviour in the Council of the European Union.

Huygens, Niels Bohrweg 2, 2333 CA, Leiden

A modeling approach with applications to the Bau de l'Aubesier (Southeastern France)

I would like to investigate what are the philosophical and practical consequences a reappraisal of the 17th-and 18th-century concept of taste may have for general and historical performance practice.

Most of current public-key cryptography is considered insecure against attacks from sufficiently powerful quantum computers. Post-quantum cryptography studies methods to secure information resistant against such attacks. One proposal is isogeny-based cryptography, which bases its security on computational…

Chapter by Fabio Cristiano and Emilio Distretti for the volume The Aesthetics and Politics of the Online Self, edited by Donatella Della Ratta, Geert Lovink, Teresa Numerico, and Peter Sarram for Palgrave Macmillan.

Detecting nanoscopic objects plays an important role in nanoscience in particular, in the rapidly growing field of nanobiology. The forebear to modern super-resolution microscopy for single molecule investigation, is fluorescence microscopy.

This volume offers a multidisciplinary view of cutting-edge research on bilingualism in Spanish and Portuguese-speaking regions, with the aim of building a bridge between sub-fields and approaches that often find themselves isolated from one another.

In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

This thesis consists of three papers that are centered around the common theme of Hausdorff uo-Lebesgue topologies and convergence structures on vector lattices and on vector lattices and vector lattice algebras of order bounded operators.

The primary goal of this research is to deepen our understanding of substrate-enzyme interactions in Glycoside hydrolases. For this purpose, Bacillus circulans xylanase (BcX) has been selected as a well-established model to examine the Michaelis complex and glycosyl-enzyme adduct.

The research connected to this topic is related to Work and health.

On the 15th of April, Shaoyu Wang successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Shaoyu on this achievement!

MPs in the Netherlands are first and foremost motivated by their direct environment, i.e. the parliamentary and partisan institutions.

Fighting for the faith, caring for the sick, and praying for the soul of their benefactors were the main tasks of the military orders, who since the time of the crusades were well represented in the Netherlands in the Middle Ages, including the Frisian lands. Especially the Hospitallers and the Teutonic…

This volume is the outcome of collaborative European research among archaeologists, archaeobotanists, ethnographers, historians and agronomists, and frequently used experiments in archaeology.

On the 6th of November, Niels Schoubben successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Niels on this achievement!

This book offers a concise and accessible introduction to debates about expertise, policy-making and democracy. It uniquely combines an overview of recent research on the policy role of experts with discussions in political philosophy and the philosophy of expertise.

Morphometric and morphological differences have been used extensively in the past to study domestication of the wolf and the origin of dogs. Certainly before genetic testing was performed, these methods were the only means to diverge both groups. But still now, when aDNA cannot be extracted, morphometry…

Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.

Promotor: S.J. Edixhoven, Co-promotor: K.J. Batenburg

In this paper, Kantorowicz aims to track the persistent effect of former partitioning borders on property tax rates in Poland.

-

Formulation of biopharmaceuticals

In a modernist interpretation of migration controls, nation states play a major role. This book challenges this interpretation by showing that comprehensive migration checks and permanent border controls appeared much earlier, in early modern dynastic states and empires, and predated nation states by…

The neolithization of the southern Netherlands in an antropological and geographical perspective

Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent

'Politics of Withdrawal' considers the significance of practices and theories of withdrawal for radical thinking today.

Self-assembly offers a promising route to create complex structures and materials using simple building blocks. Through, colloidal self-assembly, we can understand the governing principles of the self-assembly process and unlock its potential in diverse applications in materials science, photonics and…

This dissertation takes a technological approach to ceramic production and provides a fine-grained view of the circum-Caribbean region.

This book is an examination of why and how the elective principle, already established in Transylvanian and Polish political culture in the late medieval period, was transformed in the early elections of the 1570s.

Promotor: Prof.dr. J.N. Kok

On Tuesday 26th September Jessica Hill defended her thesis ‘On the road to adulthood. Delinquency and desistance in Dutch emerging adults’. The supervisor is Professor Arjan Blokland.