The advanced insights obtained for the CNS PBPK model development are currently used to develop advanced mathematical models for drug distribution prediction in other body tissues protected by barriers, such as the gut. The gut PBPK model will be linked to drug effects for treatment of colon cancer.

Elena Maria Rossi is fascinated by black holes. Her appointment as a professor was a long-held wish, partly because there are so few female professors in her field. ‘My appointment is also a milestone for the Leiden Observatory.’

The monthly ILS Lunch Seminars unite the several Institutes situated within Leiden Law School. On Thursday 15 February 2018 from 12:00 hrs until 13:00 hrs in KOG B0.41, the next edition of the ILS Lunch Seminars will take place.

Back in 2008, Jason Laffoon moved from Chicago to Leiden. He came to join the Faculty of Archaeology’s Caribbean research group as a PhD candidate. Now he is an assistant professor, bridging departments through his innovative research methods. ‘I focus both on the archaeology of the Americas, as well…

Amerindian settlement patterns and early colonial cartography in Northern Hispaniola

Imagining Urban Complexity introduces passionate and critical perspectives on the link between the humanities and urban studies.

How did nineteenth century scholars evaluate each other and each other’s work through more or less informal practices of peer review?

Several Spanish news outlets have published interviews with Associate Professor Eric Storm about his new book Nationalism.

The role of material culture in early colonial encounters in the Caribbean

In the week of 14 to 18 January the Lorentz workshop 'Intersecting Worlds. The Interplay of Cultures and Technology' took place at the Lorentz Center in Leiden. Attracting many scholars from across the world, the workshop explored the transformations and responses of indigenous societies around the…

Debates on political legitimacy in Dutch parliament in the 1880s, 1930s, and 1960s

This project examines the meaning of this historical place, and the way it has been used by the political institutions that have had their seat there.

An overview of the courses

From 2012 onwards the primary scholarly and media focus in regard to foreign fighters has been on the large number of Westerners joining jihadist groups in Syria and Iraq. Yet, much less attention has been paid to another conflict in the ring around Europe that attracted foreign fighters: the Russo-Ukrainian…

The project Going Dutch investigates why the link between being or becoming Dutch, and knowledge of Standard Dutch is so often taken for granted in public discourse, by diving into its historical roots.

Forum essays provide a framework for intellectual exchange and debate about the role of diplomacy around a particular theme. The essays are argumentative contributions and are shorter than research articles.

A mere day after setting foot ashore in the Bahamas on October 13th 1492, Christopher Columbus notes the broad foreheads of the inhabitants of the Americas. These permanently altered cranial shapes are deliberately created through the application of pressure to the head of the infant in the first years…

Drawing on a broad array of sources, this project examines modern retrievals of Bacon’s idols, thereby testing Justus von Liebig’s intriguing observation, back in 1863, that Bacon’s name lived on mainly in mottos or stereotypical phrases. More importantly, it examines the rhetorical purposes served…

This project traces how, why, and under what circumstances scholars invoked the trope of “dogmatism,” especially in controversies. Relevant controversies from various fields, periods, and countries will be subjected to in-depth rhetorical analysis.

In comparing a selection of 18th-century histories to a representative sample of 19th-century histories of science, this project inquires: Which early modern vices persisted into the 19th century and to what extent were those vices embodied in anecdotes, conveyed through commonplaces, or symbolically…

If idioms employed in codes of conduct could be as idiosyncratic as examples suggest, then to what extent did early modern language of vice, too, persist in this genre?

This project analyzes to what extent hodegetical textbooks relied on each other in warning their readers against vicious habits, how much continuity their catalogs of vice displayed, and to what extent vices that persisted throughout the 18th and 19th centuries were associated with easy-to-remember…

The project examines the political conflict in the Red River Valley of Louisiana between the majority-black Republican Party and the overwhelmingly white Democratic Party by studying the composition and actions of each party.

Providing a valuable overview of regionalism throughout the entire continent, Regionalism in Modern Europe combines both geographical and thematic approaches to examine the origins and development of regional movements and identities in Europe from 1890 to the present.

In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…

How was the future United Nations Organization promoted to global publics during WW II?

Where did the new generation of antislavery activists get their inspiration to organize in large-scale pressure groups?

Estudio arqueológico de la primera ciudad española en la Tierra Firme de América: Santa María de la Antigua del Darién

A multiple isotope approach to human-animal dynamics in the Lesser Antilles across the historical divide

This project focuses on two Mayan languages in contact: Awakateko and K’iche’. With the aim to create a database to be accessible to researchers, students, and indigenous activists interested in Mayan languages, this project will train Mayan speakers on transcription, translation, and analysis of…

According to a new study by an international team of researchers from the Caribbean, Europe and North America, the Caribbean was settled by several successive population dispersals that originated on the American mainland.

What can continuity and change in the manufacturing of locally made ceramics from the early colonials Spanish towns of Concepción de la Vega, Cotuí and Nueva Cádiz (1492-1600) tell us about the choices people made in ceramic production as a reaction the the changing social environment?

It is integral to many cluster members’ research to use Medieval and Early Modern Arts as a lens for studying the medieval and early modern periods at large:

Bringing Dominican indigenous collections back to the community

Publishing about your research is a key aspect of your career as a researcher; the majority of research publications are written in English. When applying for research funding, too, it is very important to ensure that your application is written in clear, accessible English. Maria Sherwood-Smith, Academic…

Un)timely Crises explores how ‘crisis’—as a narrative, concept, grammar, and experience—structures time and space. This collectively written volume extends Bakhtin’s ‘chronotope’ to challenge mobilizations of crisis within neoliberal governmentality. The book explores how contemporary crises can trigger…

Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown

OB associations are loose groups of young, massive stars. They constitute the last stage of the massive starformation process, and the context in which new stars are formed.

Taking as a point of departure the Italian American community in Boston and its process of collective remembrance surrounding Saint Anthony’s Feast, we address the limits and potential of montage.

A century ago, it was unclear whether the stars in the sky were clustered in groups, or widely spread in the universe.

Among Leiden’s Firsts was Hajjah Maria Ulfah Soebadio Sastrosatomo. In 1933, she was the first Indonesian woman student to earn a law degree.

Kazimierz Twardowski (1866-1938) is the founder of the Lvov-Warsaw School with its strong tradition in logic and its scientific approach to philosophy. Twardowski’s unique way of doing philosophy, his method, is of central importance for understanding his impact as a teacher.

The precolonial inhabitants of the Caribbean islands communicated, travelled, and exchanged objects and ideas along an expansive inter-island network. New methods of computer modeling shed light on these networks. Emma Slayton is set to discuss her work on this topic at her Defense on the 12th of Se…

This network brings together scholars whose work explores how contemporary frameworks of crisis produce experiences of the present, rehash or disrupt established narratives of the past, and broker specific outlooks on the future. We collaborate in studying these crisis-scapes and exploring how they…

How was the Scholarly Self cultivated in professorial families of the humanities, in German-speaking Europe between 1860 and 1930?

How did parties as political organizations emerge?

The revolutionary organizations in Paris and Berlin around 1848.

This project tries to explain the persistence of this cultural repertoire by zooming in on (1) interaction between idioms (cultural repertoires) available to scholars at certain points in time, (2) mechanisms that help transmit repertoires across time and place, and (3) rhetorical purposes for which…