The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.

This is special issue of the journal Language & Communication. The papers of this issue delve into the multifaceted realm of (non)belonging.

Changing burial rites in Early Medieval Northern Gaul, 450-600 CE

Serial learners: interactions between Funnel Beaker West and Corded Ware communities in the Netherlands during the third millennium BCE from the perspective of ceramic technology

This article introduces the concept of Repertoires of Comparison (RoCs) to explain how certain comparisons become deeply embedded in social and political life.

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Shared, general-purpose labs.

This article aims to provide a coherent foundation for empirical studies of interpersonal discussion on risk.

This inspiring collection adds stories to the fact that 68% of PhDs in the Netherlands continue their career outside academia.

Environmental challenges such as plastic pollution and biodiversity loss require extensive monitoring. Citizen science, in which members of the public participate in scientific research, has therefore become an important approach in environmental science.

This project aims to produce empirical data on migration processes in non-Western locales, and to contribute to migration studies theory-building with new insights and through comparative perspective.

Enforcement of group cooperation fails because of discriminatory punishment, according to research by Welmer Molenmaker and colleagues. When group members have different backgrounds, punishment turns into a double-edged sword: no longer used just to prevent group exploitation, but also to break the…

How interdisciplinary teaching supports the development of students’ competencies

This research tries to create a coherent comprehension of misfit, enhance conceptual knowledge, highlight prevalent knowledge.

This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.

Promotor: S.J. Edixhoven, L.D.J. Taelman

This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

How do we define the works of a film director whose films cross many established boundaries at once?

This collection of essays explores processes of innovation in Greco-Roman technology and science.

On the first day at a new job, you have sweaty palms, nerves race through your system, and you feel insecure. Now, a couple of months later these feelings have left. You know what to do in your new role and have become part of the organization. The process leading to this result is called organizational…

Today, knowledge is the most crucial element to stimulate organizational competitiveness and economic development.

Chinese materia medica (CMM), comprising a diverse array of natural substances from plants, animals, and minerals, has been integral to Traditional Chinese Medicine (TCM) throughout history. This study investigates the dynamic evolution of CMM, noting shifts in species for improved therapeutic effects…

This paper explores how citizenship is enacted and experienced in welfare encounters for Egyptian migrant parents in Paris, Amsterdam, and Milan, highlighting the importance of social citizenship and personal interactions in shaping belonging.

This thesis covers several aspects of quantum algorithms for near-term quantum computers and its applications to quantum chemistry and material science.

This dissertation develops an innovative approach to cultural transformation in the kingdom of Commagene (modern south-east Turkey) during the 1st c. BCE, focusing on a palatial context in the capital Samosata.

During adolescence, mood disorder onset peaks. Mood variability is associated with negative mental health outcomes, so understanding biological factors that might be associated with mood variability, such as sleep and structural brain development, could elucidate the mechanisms underlying mood and anxiety…

In this thesis three different topics in number theory are studied.

Promotor: Prof.dr. E. R. Eliel, Co-Promotor: M.J.A. de Dood

Promotores: Prof. Dr. Th.J.C. van Berkel, Prof. Dr. M. van Eck

In this thesis we have discussed several parameters that affect the electrochemical conversion of enviromentaly harmful molecules such as nitrates and carbon dioxide to more valuable and less deleterious compounds, in order to cast light onto the mechanism of the reaction to achieve an efficient and…

Anthropogenic change is reshaping ecological systems, raising concerns about increasing transmission of infectious diseases. Among these, mosquito-borne diseases may be particularly sensitive to environmental change, as their transmission depends on vector populations.

Nature uses a special class of histone proteins, histone variants, to modulate the properties of chromatin at defined genomic locations.

This project aims at determining the market value of hydrogen peroxide (HP) that is produced via our electrochemical methods that have been developed as part of the ERC-StG Cu4Energy project.

Social evaluative fears during adolescence

The shift from response to recovery is now noticeable as the world moves past the paralyzing effects of the COVID-19 pandemic. This book explores responses to the pandemic by international, regional, and local institutions, multilateral action, and crisis prevention efforts at different levels of governance,…

Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra

Op 17 November 2020, Shuai Guo defended his thesis 'Recognition of Foreign Bank Resolution Actions'. The doctoral research was supervised by Prof. R.D. Vriesendorp and Prof. M. Haentjens.

Leiden University, Department of Economics

The parabolic Anderson model (PAM), which is the Cauchy problem for the heat equation with random potential. The PAM is a mathematical model that describes how mass (i.e. matter or energy) flows in a medium in the presence of a field of sources and sinks.

In 'The Spirit of Matter', Peter Pels explores the significance of emotionally evocative objects, challenging the denial of their existence in modern 'mind over matter' ideology.

Protoplanetary disks are the gas and dust environments where planetary systems form around young stars. Using observations from the Atacama Large Millimeter/submillimeter Array (ALMA) this thesis analyses the gaseous molecular reservoir, using multiple tracers to resolve the 3D structure of protoplanetary…

This dissertation is a collection of four research articles devoted to the study of Kummer theory for commutative algebraic groups.

Objects, Appropriation and Cultural Change

On the 12th of February, Cid Swanenvleugel successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Cid on this achievement!

On Wednesday 13 December 2017 Jaap Wieland defended his doctoral thesis entitled ‘De bescherming van concurrentiebelangen in het bestuursrecht’ (the Protection of Competition Interests in Administrative Law).

This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…

Light obscuration (LO) is the current standard technique for subvisible particle analysis in the quality control of parenterally administered drugs, including therapeutic proteins.

A quantitative study on the use of pre-trial detention of juveniles in The Netherlands.

The studies outlined in this volume explore how connectedness continues to change Africa and how Africa continues to shape the social life of connections.