Protoplanetary disks are the gas and dust environments where planetary systems form around young stars. Using observations from the Atacama Large Millimeter/submillimeter Array (ALMA) this thesis analyses the gaseous molecular reservoir, using multiple tracers to resolve the 3D structure of protoplanetary…

This dissertation is a collection of four research articles devoted to the study of Kummer theory for commutative algebraic groups.

Objects, Appropriation and Cultural Change

On the 12th of February, Cid Swanenvleugel successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Cid on this achievement!

On Wednesday 13 December 2017 Jaap Wieland defended his doctoral thesis entitled ‘De bescherming van concurrentiebelangen in het bestuursrecht’ (the Protection of Competition Interests in Administrative Law).

This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…

Light obscuration (LO) is the current standard technique for subvisible particle analysis in the quality control of parenterally administered drugs, including therapeutic proteins.

A quantitative study on the use of pre-trial detention of juveniles in The Netherlands.

The studies outlined in this volume explore how connectedness continues to change Africa and how Africa continues to shape the social life of connections.

Large-scale excavations at Neumark-Nord 2 (Germany), a very rich Middle Palaeolithic site with excellent preservation of organic (faunal and floral) remains and lithics in fine-grained lake deposits, dating to about 125,000 years ago.

In this Ph.D. thesis we study the interaction of low energy electrons with thin materials, namely layered materials (graphene, hexagonal boron nitride, molybdenum disulfide) and organic films. At these low energies the quantum mechanical wavelength of the electron wave function is in the order of a…

Promotor: G.R. de Snoo Co-promotor: C.J.M. Musters

The Western Mediterranean is a key region to understand human dispersal events within and out of the African continent as well as for the eventual replacement of Neanderthals by anatomically modern humans during the Pleistocene. Central to any conclusive interpretation of archaeological and palaeoclimatic…

Vietnam’s record of expanding access to education, and especially its performance on international assessments such as PISA, has raised questions about what Vietnam got right, how, and why and what insights Vietnam’s experiences might offer for efforts at improving the performance of education systems…

This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…

The Assyrian Empire was the first state to achieve durable domination of the Ancient Near East, enduring some seven centuries and, eventually, controlling most of the region. Yet, we know little about how this empire emerged from a relatively minor polity in the Tigris region and how it managed to consolidate…

Promotor: K.H. Kuijken

In this paper, Sarah Giest and Bram Klievink highlight the effects of AI implementation on public sector innovation. This is explored by asking how AI-driven technologies in public decision-making in different organizational contexts impacts innovation in the role definition of bureaucrats.

A dental anthropological approach to foodways, health and disease, and crafting in the pre-Columbian Caribbean.

How citizens and professionals are the key to successful collaboration in the delivery of public services. How do individual characteristics of citizens and professionals influence citizen-professional collaboration in the co-production of public services?

Gold nanoparticles show surprisingly strong interactions with light in the visible range, which can be divided into scattering, absorption, and photoluminescence.

Chapter 1,contains the numerical verification of the Birch and Swinnerton-Dyer conjecture for hundreds of Jacobians of hyperelliptic curves of genus 2, 3, 4 and 5.

The use of increasingly large and diverse datasets to guide urban climate action has implications for how, and by whom, local governments are held accountable.

During the period 500–1000 CE Egypt was successively part of the Byzantine, Persian and Islamic empires. All kinds of events, developments and processes occurred that would greatly affect its history and that of the eastern Mediterranean in general. This is the first volume to map Egypt's position in…

We are proud to announce that the 1st Volume of INTER-SECTION is now available.

Throughout history, a large portion of the world's population has lived under imperial rule. Although scholars do not always agree on when and where the roots of imperialism lie, most would agree that imperial configurations have affected human history so profoundly that the legacy of ancient empires…

Perec’s Lieux project consists of texts describing the author's places of memory, photographs, personal documents and ephemera collected in the street.

The aim of this thesis was to develop novel treatment strategies for different types of eye melanoma utilizing zebrafish models. We first establish orthotopic and ectopic xenograft models for uveal and conjunctival melanoma by engraftment of the immortalized cells derived from these tumors into zebrafish…

Food security is challenged by a growing global population and by climate change. Drought and soil salinity are considered the most important ones that inhibit crop yield and distribution. Worryingly, climate change is predicted to increase not only their frequency and severity, but also their co-occurrence,…

In Migration and Membership Regimes editors Ulbe Bosma, Gijs Kessler and Leo Lucassen bring together ten essays in an analytical framework which looks beyond the Transatlantic migration of the nineteenth and twentieth centuries in a deliberate attempt to incorporate the experience of earlier periods…

Galaxies form and evolve through close interaction with their surroundings. As a result, the heavy elements ('metals') that are synthesized in stars, are found both inside and outside galaxies.

BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.

This book is about what happens when two people meet. Its main aim is to present an account of intersubjectivity.

Considering the ways in which the ‘global turn’ is changing the theory and practice of historical disciplines, Explorations in History and Globalization engages with the concept and methodology of globalization, challenging traditional divisions of space and time to offer a range of perspectives on…

This thesis develops a method for direction dependent calibration of the ionosphere in radio interferometric data.

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The main aim of this research is to understand the dynamics of identity within indigenous Caribbean communities as expressed through the practice of intentional cranial modification. A multidisciplinary approach will be applied to achieve this aim, combining current anthropological and sociological…

Henk Versnel's work on ancient religion has been seminal. For his 80th birthday, a group of scholars assembled to celebrate and analyze his oeuvre.

While phenomenology and Yogacara Buddhism are both known for their investigations of consciousness, there exists a core tension between them: phenomenology affirms the existence of essence, whereas Yogacara Buddhism argues that everything is empty of essence (svabhava). How is constructive cultural…

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-Promotor: J.D.C. Codee

Dr. Nikki Ikani challenges binary views of intelligence warnings, proposing a multidimensional typology to evaluate warning effectiveness.

Evert Jan van Leeuwen’s entry in Auteur Press’s Devil's Advocate series provides a complete study of the aesthetic appeal of Roger Corman's influential first Poe picture House of Usher.

Over the past years it has been discovered that the population of extra-solar planets is large and diverse.

This engagingly written textbook provides a unique 'hands-on' introduction to sociolinguistics, which equips readers with the tools to start their own sociolinguistic research project.

The Department of Child Law collaborated on a study on missing children in the European Union for the European Commission. The outcomes of the study aim to help to improve the mechanisms involved when children are missing in EU Member States.

Did early farmers deliberately use animal manure on their fields?

On 22 November 2018, Els De Busser spoke at a panel during the conference

The Low Frequency Array enables studies of low-frequency carbon radio recombination lines with unprecedented sensitivity, spectral and spatial resolution.

Promotor: Prof.dr. J.P. Abrahams

This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.