The Biological- and Soft-Matter Physics Master specialisation is one of the two programmes Leiden offers in experimental Physics. The programme can to a high degree be tailored to individual needs and interests.

Located in the friendly small city of Leiden in the centre of the Netherlands, Leiden University has for centuries been at the forefront of developments in science and that excellent continues today, with world-leading institutes of computer science, mathematics, physics, astronomy, and chemistry. …

Your time at Leiden is about more than just studying. Some of your best experiences will stem from being a part of our lively and diverse student community, as well as from life in the beautiful city of Leiden.

Your time at Leiden is about more than just studying. Some of your best experiences will stem from being a part of our lively and diverse student community, as well as from life in the beautiful city of Leiden.

Your time at Leiden is about more than just studying. Some of your best experiences will stem from being a part of our lively and diverse student community, as well as from life in the beautiful city of Leiden.

Your time at Leiden is about more than just studying. Some of your best experiences will stem from being a part of our lively and diverse student community, as well as from life in the beautiful city of Leiden.

Since 2008 every half a year an SBB student starts with an internship for Merck Serono Ventures in Geneva. Head of the company Roel Bulthuis selects and works with the SBB interns and shares his experiences as an employer. He is very pleased.

Anyone who creates a page for a magazine, a PowerPoint presentation, a brochure, a poster or dreams up an idea for an infographic is faced with important questions:

Theoretical physicist Stephen Hawking (76) passed away on 14 March at his home in Cambridge, having been a long-term sufferer of the muscular disease ALS. A number of Leiden scientists look back at the life and scientific career of this world-famous physicist. 'He was very approachable and extremely…

Those who know their dystopian classics will inevitably associate the concept of surveillance society with the all-knowing oppressive force characterized as Big Brother in George Orwell’s novel 1984. However, surveillance permeats our society in many more subtle aspects than our worst fears about spy…

Leiden University invites pre-applications from scholars who wish to spend 12-24 months in the Institute of Political Science as part of the Marie Skłodowska-Curie Individual Fellowship Programme.

How do you microscopically image zebrafish larvae? The new free online course ‘Imaging the Vertebrate embryo’ teaches you all about it. Leiden PhD candidates Salomé Muñoz Sánchez and Radoslaw Gora contributed to the course.

Once a year, former employee and avid runner Dennis Hoencamp returns to his old workplace. That’s when he competes in the Leiden Science Run. As an event coordinator, he once devised the relay race as an anniversary activity. It grew into an annual event for the entire University and the Bio Science…

Jet Bussemaker, former Minister of Education, Culture and Science, has been appointed Professor at Leiden University Medical Center (LUMC) and Leiden University with effect from 1 July 2018. She will be the holder of the new chair in ‘Science, Policy and Societal Impact, focusing on Healthcare'.

Science Letter

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.

This thesis is about augmented reality (AR). AR is commonly considered a technology that integrates virtual images into a user’s view of the real world.

The Graduate School of Science offers 9 PhD programmes, spanning the entire spectrum of science. Do you have a Master's degree and are you proficient in English? Do you share a fascination for science? Then you may find the Graduate School of Science an inspiring and ideal environment for obtaining…

On this section of the website you can find more information about the Old Observatory and the current astronomy research institute.

This work has described synthetic strategies towards well-defined structures resembling capsular polysaccharide (CPS) fragments, CPS mimics, teichoic acid (TA) fragments as well as a third-generation ring-closing tandem metathesis (RCM) linker to better exploit the potential of automated synthesis.

The marine shipping industry is one of the strongest emitters of nitrogen oxides (NOx), a pollutant detrimental to ecology and human health. Over the last 20 years, the pollution produced by power plants, the industry sector, and cars has been decreasing.

This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.

Carbohydrates, or sugars, are the most diverse and most abundant biomolecules known. However, the isolation of carbohydrate samples in sufficient amounts and purity is often impractical or even impossible, so the chemical synthesis of glycosides becomes relevant. The glycosylation reaction, in which…

In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.

Ehrenfestgarage, Emmy Noetherweg , 2333BK, Leiden

In this thesis I highlight the applications of Oxford Nanopore Technologies (ONT) sequencing. This technique is a relatively new approach in the sequencing field, where nanopores are embedded in a membrane, DNA molecules are pulled through nanopores and an electrical current serving as the sequencing…

Antibiotic resistance, caused by widespread use of antibiotics, leads to bacterial infections that are difficult, if not impossible, to treat and is a major worldwide health concern.

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

Many researchers of the Faculty of Science are members of a research school related to their area of expertise. Research schools aim at collaboration of researchers from different faculties in the same university (interfaculty schools) or in different universities (interuniversity schools).

Promotor: G.A. van der Marel, Co-promotor: D.C. Codée

Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.

Leiden University wants its research and teaching to have a positive impact on society. In an effort to achieve this, many of our researchers collaborate with academic and community partners, non-governmental organisations and the business sector.

Het is een wijdverbreid idee dat (post-)middeleeuwse steden een sterfteoverschot hadden en zij slechts in leven konden blijven door de toestroom van migranten; een fenomeen dat bekend staat als het ‘urban graveyard’-effect. Over details valt te twisten, maar duidelijk is dat de stad en de dood dichter…

The Study Information Committee works to create a positive and accurate picture of the bachelor and master programs offered by the Institute of Biology Leiden (IBL). The committee consists of IBL staff members and study ambassadors. We reach out to future and current students, high school biology teachers,…

One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.

In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.

This Thesis describes a strategy to synthesize 1,2-cis-oligosaccharides modulated by additives, such as dimethylformamide (DMF), triphenylphosphine oxide (Ph3P=O) and N-methyl(phenyl)formamide (MPF), using building blocks that carry solely benzyl type protecting groups and are therefore of uniform r…

The new building for the Faculty of Mathematics and Natural Sciences is a significant milestone for Leiden University and the faculty in particular. A new building is being realized in three phases. The first phase of the new building was put into use in 2016 and covers an area of 45,000m2. The second…

The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.

Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.