4,204 search results for “leiden bio science paul” in the Public website
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P.J. VethNonnensteeg 1-3, Leiden
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Why Leiden University?
The Computer Science and Education master specialisation gives you the opportunity to combine computer science research with an excellent education in becoming a teacher.
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Student life
Your time at Leiden is about more than just studying. Some of your best experiences will stem from being a part of our lively and diverse student community, as well as from life in the beautiful city of Leiden.
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Why Leiden University?
Combine research in Computer Science with different aspects of business studies and learn how to build bridges between science and business.
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Student life
Your time at Leiden is about more than just studying. Some of your best experiences will stem from being a part of our lively and diverse student community, as well as from life in the beautiful city of Leiden.
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Student life
Your time at Leiden is about more than just studying. Some of your best experiences will stem from being a part of our lively and diverse student community, as well as from life in the beautiful city of Leiden.
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ESOF2022: Leiden Law School
EuroScience Open Forum – ESOF - is Europe’s biggest multidisciplinary and prestigious scientific conference. ESOF2022 will take place from 13-16 July 2022 and is hosted by Leiden as the European City of Science (in the Netherlands). The Kamerlingh Onnes Building is one of the locations of the ESOF and…
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Working with SBB Interns. By Roel Bulthuis of Merck Serono
Since 2008 every half a year an SBB student starts with an internship for Merck Serono Ventures in Geneva. Head of the company Roel Bulthuis selects and works with the SBB interns and shares his experiences as an employer. He is very pleased.
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SUPER MoRRI Annual event 2020: RRI across Europe: Exploring the science society interface
On January 29th, the first annual event of the SUPER MoRRI project will be held in the Lipsius building in Leiden and will be thematically organized around engaging the public with research and innovation. Registration is free; hope to see you there!
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Visual Language
Anyone who creates a page for a magazine, a PowerPoint presentation, a brochure, a poster or dreams up an idea for an infographic is faced with important questions:
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Michael Meffert
Faculty of Social and Behavioural Sciences
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Social Science Matters: The surveillance society
Those who know their dystopian classics will inevitably associate the concept of surveillance society with the all-knowing oppressive force characterized as Big Brother in George Orwell’s novel 1984. However, surveillance permeats our society in many more subtle aspects than our worst fears about spy…
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Free online course teaches you all about imaging
How do you microscopically image zebrafish larvae? The new free online course ‘Imaging the Vertebrate embryo’ teaches you all about it. Leiden PhD candidates Salomé Muñoz Sánchez and Radoslaw Gora contributed to the course.
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'Stephen Hawking put abstract science on the map'
Theoretical physicist Stephen Hawking (76) passed away on 14 March at his home in Cambridge, having been a long-term sufferer of the muscular disease ALS. A number of Leiden scientists look back at the life and scientific career of this world-famous physicist. 'He was very approachable and extremely…
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Back to Leiden for the Science Run: ‘As founder, I just have to participate'
Once a year, former employee and avid runner Dennis Hoencamp returns to his old workplace. That’s when he competes in the Leiden Science Run. As an event coordinator, he once devised the relay race as an anniversary activity. It grew into an annual event for the entire University and the Bio Science…
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Jet Bussemaker appointed Professor of Science, Policy and Impact in Healthcare
Jet Bussemaker, former Minister of Education, Culture and Science, has been appointed Professor at Leiden University Medical Center (LUMC) and Leiden University with effect from 1 July 2018. She will be the holder of the new chair in ‘Science, Policy and Societal Impact, focusing on Healthcare'.
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Towards a Circular Food System: Global Resource Losses, Waste Typologies, and Valorization Pathways
Food waste is a defining inefficiency of the modern food system, with profound implications for resource use, climate change, and circular economy transitions. This dissertation examines food waste through two complementary lenses: the prevention of avoidable food waste and the valorization of unavoidable…
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Research Schools
Many researchers of the Faculty of Science are members of a research school related to their area of expertise. Research schools aim at collaboration of researchers from different faculties in the same university (interfaculty schools) or in different universities (interuniversity schools).
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Study Information Committee
The Study Information Committee works to create a positive and accurate picture of the bachelor and master programs offered by the Institute of Biology Leiden (IBL). The committee consists of IBL staff members and study ambassadors. We reach out to future and current students, high school biology teachers,…
- Prof Dr Consuelo De Moraes
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Structure-reactivity relationships in glycosylation chemistry
In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.
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From pixels to patterns: AI-driven image analysis in multiple domains
This thesis investigates the application of deep learning techniques in image analysis across various domains, focusing on four main themes: feature extraction, classification, segmentation, and integration, demonstrating the transformative potential of these technologies.
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Chemical tools to study lipid signaling
Synthesis and application of chemical biology tools to study immunomodulatory signaling lipids.
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Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
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Image analysis for gene expression based phenotype characterization in yeast cells
Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek
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Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
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Metabolic signatures in nutrition and health: short-term diet response, sexual dimorphism and hormone chronobiology
The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).
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PhD position
Develop EPR instrumentation and methodology to investigate intrinsically disordered proteins (IDPs).
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Collaborations
Ecotox is located in an ambitious surrounding at the Leiden University. It is an initiative of both institutes Institute of Environmental Sciences (CML) and Institute of Biology Leiden (IBL).
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Development of personalized health monitoring using ultra-weak photon emission based on systems medicine concepts
Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk
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Visual Relation extraction Based on Deep Cross-media Transfer Network
Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.
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1,2-cis-glycosylations: method development and synthesis of complex oligosaccharides
Promotor: G.A. van der Marel, Co-promotor: D.C. Codée
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Chemical tools to modulate endocannabinoid biosynthesis
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Ehrenfest parking garage
Ehrenfestgarage, Emmy Noetherweg , 2333BK, Leiden
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Arguably augmented reality : relationships between the virtual and the real
This thesis is about augmented reality (AR). AR is commonly considered a technology that integrates virtual images into a user’s view of the real world.
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Bioorthogonal chemistry to unveil antigen processing events
The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.
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Stereoelectronic and conformational effects in oxocarbenium, iminium and iminosugar ammonium ions
Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée
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In vivo fluorescence imaging of IgG1 aggregates after subcutaneous and intravenous injection in mice
PURPOSE: To monitor the biodistribution of IgG1 aggregates upon subcutaneous (SC) and intravenous (IV) administration in mice and measure their propensity to stimulate an early immune response.
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The Observatory
On this section of the website you can find more information about the Old Observatory and the current astronomy research institute.
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Becoming a PhD candidate
The Graduate School of Science offers 9 PhD programmes, spanning the entire spectrum of science. Do you have a Master's degree and are you proficient in English? Do you share a fascination for science? Then you may find the Graduate School of Science an inspiring and ideal environment for obtaining…
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Towards a mechanistic understanding of nanoparticle behavior using zebrafish
The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.
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Knowledge Extraction from Archives of Natural History Collections
Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.
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Chemical Synthesis of Fragments of Streptococcal Cell Wall Polysaccharides
This thesis describes the design and synthesis of fragments of various cell wall carbohydrates of the Streptococcus species, including the branched Group B-specific antigen (GBC) of Group B Streptococcus, glycerol phosphate (GroP) modified group A carbohydrate (GAC), and the O-acetylated type 1 capsular…
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Shape Analysis for Phenotype Characterisation from High-throughput Imaging
We have studied shape with a particular focus on the zebrafish model system. The shape is an essential appearance of the phenotype of a biological specimen and it can be used to read out a current state or response or to study gene expression.
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Bacterial glycomimetics: synthesis and applications
This work has described synthetic strategies towards well-defined structures resembling capsular polysaccharide (CPS) fragments, CPS mimics, teichoic acid (TA) fragments as well as a third-generation ring-closing tandem metathesis (RCM) linker to better exploit the potential of automated synthesis.
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Synthetic carbohydrate ligands for immune receptors
One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.
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Glycosyl Cations in Glycosylation Reactions
This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.
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Computational and experimental studies of reactive intermediates in glycosylation reactions
Carbohydrates, or sugars, are the most diverse and most abundant biomolecules known. However, the isolation of carbohydrate samples in sufficient amounts and purity is often impractical or even impossible, so the chemical synthesis of glycosides becomes relevant. The glycosylation reaction, in which…
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Inhibitors and activity-based probes for β-D-glucuronidases, heparanases and β-L-arabinofuranosidases
Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.
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Synthesis and application of glycans unique to S. Mansoni
Schistosomiasis is an acute and chronic disease caused by blood dwelling parasitic trematodes of the genus Schistosoma, and it is classified as the second most socioeconomically devastating parasitic disease, second only to malaria.
