The second and final report on the Netherlands‘ crime-terror nexus has analysed all fourteen profiles of individuals arrested in 2015 for offences of terrorism.

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. D. Tibboel (EMC, R’dam)

The Quantitative Clinical Pharmacology group is led by Prof. Dr. Catherijne Knibbe. Her research group aims to define how to adjust a drug dose in special patient populations such as (prematurely born) neonates or children, obese individuals or critically ill patients. Through combining the statistical…

The Corfu Papers

Reinforcement learning is a framework that enables agents to learn in a manner similar to humans, i.e. through trial and error. Ideally, we would like to train a generalist agent capable of performing multiple tasks and achieving various goals.

This research note argues that the “lone wolf” typology should be fundamentally reconsidered.

Promotor: Prof.dr. B. van de Water, Co-promotor: E.H.J. Danen

The aim of current study was to develop a dried inactivated polio vaccine (IPV) formulation with minimal loss during the drying process and improved stability when compared with the conventional liquid IPV.

This dissertation assesses the influence of British Celtic on the phonological development of English during and shortly after the Anglo-Saxon settlement period, ca. AD 450-700.

The Early Upper Palaeolithic (EUP) record throughout Europe is characterized by major changes in human behaviour.

The Faculty of Science is housed in various buildings situated in the Bio Science Park Leiden.

Diacylglycerol lipases (DAGLα and DAGLβ) convert diacylglycerol to the endocannabinoid 2-arachidonoylglycerol. Our understanding of DAGL function has been hindered by a lack of chemical probes that can perturb these enzymes in vivo.

Aluminium-based adjuvants, such as aluminium hydroxide and aluminium phosphate, are well-known for their immune-stimulating properties.

This is the team of LAPP:

Does the δ-machine have higher accuracy than the other feature-based classifiers in some conditions?

An overview of new research project: Politeness in Arabic Papyrus Letters

Several studies into the prevalence of child abuse in the Netherlands were conducted on behalf of the Ministries of Security and Justice and of Health, Welfare and Sport, the Samson Committee and the WODC.

Source: J Med Chem, Volume 57, Issue 8, pp. 3213-22 (2014)

Green infrastrucuture (GI) like urban farm and green roofs could provide many beneficial functions in cities. These include for example food production, flood prevention or increasing biodiversity. MultiGreen project aims at developing an integrated modelling tool to support…

Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…

I would like to investigate what are the philosophical and practical consequences a reappraisal of the 17th-and 18th-century concept of taste may have for general and historical performance practice.

The primary goal of this research is to deepen our understanding of substrate-enzyme interactions in Glycoside hydrolases. For this purpose, Bacillus circulans xylanase (BcX) has been selected as a well-established model to examine the Michaelis complex and glycosyl-enzyme adduct.

MPs in the Netherlands are first and foremost motivated by their direct environment, i.e. the parliamentary and partisan institutions.

We invite proposals for workshops and tutorials, to be held in Leiden on 01 July 2024 (deadline passed).

This book offers a concise and accessible introduction to debates about expertise, policy-making and democracy. It uniquely combines an overview of recent research on the policy role of experts with discussions in political philosophy and the philosophy of expertise.

Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.

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Formulation of biopharmaceuticals

This dissertation takes a technological approach to ceramic production and provides a fine-grained view of the circum-Caribbean region.

Current clients

Promotor: A.P.IJzerman Co-promotor: A. Bender

This article aims to explore the determinants of inclusive leadership. This type of leadership is valued for social equity and fairness.

Deepfakes are videos that have been manipulated to replace one person’s likeness with that of another. They can be difficult to distinguish from authentic videos. In our study, we found that people who score high on conspiracy thinking and people who use social media more are better at distinguishing…

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Discovery of metastasis promoting candidate drug targets

The central question in this book is whether there is a human right to family unification.

Promotores: W.J.G.M. Peijnenburg, G.R. de Snoo, Co-promotor: M.G. Vijver

The skin protects the body from unwanted influences from the environment as well as excessive water loss. The barrier function of the skin is located in the stratum corneum (SC).

Supply risks are not new. But the aggravation of power conflicts on the international stage coupled with global shifts towards energy transition and digitalization has triggered the next supply risk research era.

In the Netherlands approximately 130 out of 700 secondary schools offer a bilingual stream. However, research about CLIL (Content and Language Integrated Learning) is limited. With her dissertation Evelyn van Kampen (PhD student at ICLON) wants to contribute to the understanding of the nature and range…

A research agenda

Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…

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The Institute Council consists of scientists, lecturers, support staff and students. They provide a forum for discussing the institute’s current situation and its prospects.

Inaugural lecture

ABPP2027 will be held in Naturalis, Leiden, The Netherlands.